Epigenetic Mechanisms in Bone Biology and Osteoporosis: Can They Drive Therapeutic Choices?

HDAC2 regulates FoxO1 during RANKL-induced osteoclastogenesis

(2016) Ce Dou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

High inorganic phosphate concentration inhibits osteoclastogenesis by modulating miR-223

(2015) Eléonore M'Baya-Moutoula et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation

(2015) Sylvia Weilner et al.   BONE

Serum Circulating MicroRNAs as Biomarkers of Osteoporotic Fracture

(2015) Layla Panach et al.   CALCIFIED TISSUE INTERNATIONAL

Methylation of BoneSOST, Its mRNA, and Serum Sclerostin Levels Correlate Strongly With Fracture Risk in Postmenopausal Women

(2015) Sjur Reppe et al.   JOURNAL OF BONE AND MINERAL RESEARCH

DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine–producing metabolic pathway

(2015) Keizo Nishikawa et al.   NATURE MEDICINE

Histone Deacetylases in Bone Development and Skeletal Disorders

(2015) Elizabeth W. Bradley et al.   PHYSIOLOGICAL REVIEWS

From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?

(2015) Katarzyna Szarc vel Szic et al.   Clinical Epigenetics

Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders

(2014) Christophe Decroos et al.   ACS Chemical Biology

Protective effects of resveratrol on postmenopausal osteoporosis: regulation of SIRT1-NF-κB signaling pathway

(2014) Jing Feng et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Plasma miRNA levels correlate with sensitivity to bone mineral density in postmenopausal osteoporosis patients

(2014) Hongqiu Li et al.   BIOMARKERS

Five Freely Circulating miRNAs and Bone Tissue miRNAs Are Associated With Osteoporotic Fractures

(2014) Claudine Seeliger et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Epigenetic mechanisms in bone

(2013) Peter Vrtačnik et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

DNA 5-Methylcytosine Demethylation Activities of the Mammalian DNA Methyltransferases

(2013) Chun-Chang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MiR-433 mediates ERRγ-suppressed osteoblast differentiation via direct targeting to Runx2 mRNA in C3H10T1/2 cells

(2013) Eun-Jung Kim et al.   LIFE SCIENCES

Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis

(2012) Jesús Delgado-Calle et al.   ARTHRITIS AND RHEUMATISM

Role of DNA methylation in the regulation of the RANKL-OPG system in human bone

(2012) Jesús Delgado-Calle et al.   Epigenetics

Interferon-β-induced miR-155 inhibits osteoclast differentiation by targeting SOCS1 and MITF

(2012) Jun Zhang et al.   FEBS LETTERS

miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells

(2012) Mohammad Q. Hassan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of miR-21 biogenesis by estrogen action contributes to osteoclastic apoptosis

(2012) Toshifumi Sugatani et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Genome-Wide Association Studies of Skeletal Phenotypes: What We Have Learned and Where We Are Headed

(2012) Yi-Hsiang Hsu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

X-exome sequencing identifies aHDAC8variant in a large pedigree with X-linked intellectual disability, truncal obesity, gynaecomastia, hypogonadism and unusual face

(2012) Magdalena Harakalova et al.   JOURNAL OF MEDICAL GENETICS

HDAC7 Inhibits Osteoclastogenesis by Reversing RANKL-Triggered β-Catenin Switch

(2012) Zixue Jin et al.   MOLECULAR ENDOCRINOLOGY

miR-142-3p promotes osteoblast differentiation by modulating Wnt signaling

(2012) WEIHUA HU et al.   Molecular Medicine Reports

A microRNA expression signature of osteoclastogenesis

(2011) T. Sugatani et al.   BLOOD

A Runx2/miR-3960/miR-2861 Regulatory Feedback Loop during Mouse Osteoblast Differentiation

(2011) Rong Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1

(2011) Jin Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

(2011) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-27 promotes osteoblast differentiation by modulating Wnt signaling

(2010) Tao Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Birth weight predicts bone size in young adulthood at cortical sites in men and trabecular sites in women from The Gambia

(2010) Stephanie de Bono et al.   BONE

Birth weight and bone mass in young adults from Brazil

(2010) Michael Maia Schlüssel et al.   BONE

The MicroRNA Spectrum in 12 Body Fluids

(2010) J. A. Weber et al.   CLINICAL CHEMISTRY

Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse

(2010) Tripti Gaur et al.   DEVELOPMENTAL BIOLOGY

Adverse effects of valproate on bone: Defining a model to investigate the pathophysiology

(2010) Susan M. Senn et al.   EPILEPSIA

Epigenetics and gene expression

(2010) E R Gibney et al.   HEREDITY

miR-29 Modulates Wnt Signaling in Human Osteoblasts through a Positive Feedback Loop

(2010) Kristina Kapinas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

(2010) David F. Razidlo et al.   PLoS One

A network connecting Runx2, SATB2, and the miR-23a 27a 24-2 cluster regulates the osteoblast differentiation program

(2010) M. Q. Hassan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase 4 promotes TGF-β1-induced synovium-derived stem cell chondrogenesis but inhibits chondrogenically differentiated stem cell hypertrophy

(2009) Ming Pei et al.   DIFFERENTIATION

Epigenetic control of skull morphogenesis by histone deacetylase 8

(2009) M. Haberland et al.   GENES & DEVELOPMENT

Low maternal vitamin D status and fetal bone development: Cohort study

(2009) Pamela Mahon et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption

(2009) Fumitaka Mizoguchi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans

(2009) Hui Li et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-204 Regulates Runx2 Protein Expression and Mesenchymal Progenitor Cell Differentiation

(2009) Jian Huang et al.   STEM CELLS

Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspring

(2008) Karen A. Lillycrop et al.   BRITISH JOURNAL OF NUTRITION

Deletion of Histone Deacetylase 3 Reveals Critical Roles in S Phase Progression and DNA Damage Control

(2008) Srividya Bhaskara et al.   MOLECULAR CELL

A microRNA signature for a BMP2-induced osteoblast lineage commitment program

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA