Epigenetic Control of Mesenchymal Stem Cell Fate Decision via Histone Methyltransferase Ash1l

Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds

(2018) Chengcheng Yin et al.   Acta Biomaterialia

Topographical cues of direct metal laser sintering titanium surfaces facilitate osteogenic differentiation of bone marrow mesenchymal stem cells through epigenetic regulation

(2018) Guoying Zheng et al.   CELL PROLIFERATION

Structure-based development of an osteoprotegerin-like glycopeptide that blocks RANKL/RANK interactions and reduces ovariectomy-induced bone loss in mice

(2018) Chao Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IGFBP7 regulates the osteogenic differentiation of bone marrow–derived mesenchymal stem cells via Wnt/β-catenin signaling pathway

(2018) Wei Zhang et al.   FASEB JOURNAL

Physiological role of urothelial cancer-associated one long noncoding RNA in human skeletogenic cell differentiation

(2018) Takanori Ishikawa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PPAR-γ and Wnt Regulate the Differentiation of MSCs into Adipocytes and Osteoblasts Respectively

(2018) Yue Li et al.   Current Stem Cell Research & Therapy

Aryl hydrocarbon receptor suppresses the osteogenesis of mesenchymal stem cells in collagen-induced arthritic mice through the inhibition of β-catenin

(2017) Yulong Tong et al.   EXPERIMENTAL CELL RESEARCH

Deduction of Novel Genes Potentially Involved in Osteoblasts of Rheumatoid Arthritis Using Next-Generation Sequencing and Bioinformatic Approaches

(2017) Yi-Jen Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Estrogen regulates stemness and senescence of bone marrow stromal cells to prevent osteoporosis via ERβ-SATB2 pathway

(2017) Geng Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tet-Mediated DNA Demethylation Is Required for SWI/SNF-Dependent Chromatin Remodeling and Histone-Modifying Activities That Trigger Expression of the Sp7 Osteoblast Master Gene during Mesenchymal Lineage Commitment

(2017) Hugo Sepulveda et al.   MOLECULAR AND CELLULAR BIOLOGY

Runt-Related Transcription Factor 2 Induction During Differentiation of Wharton's Jelly Mesenchymal Stem Cells to Osteoblasts Is Regulated by Jumonji AT-Rich Interactive Domain 1B Histone Demethylase

(2017) Francisco Bustos et al.   STEM CELLS

Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity

(2017) Meng Xia et al.   Nature Communications

The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice

(2017) Gang Li et al.   Scientific Reports

SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis

(2017) Kayvan Zainabadi et al.   PLoS One

Osteoporosis: the current status of mesenchymal stem cell-based therapy

(2016) Jitrada Phetfong et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

MicroRNA-320a Regulates the Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells by Targeting HOXA10

(2016) Jianhou Huang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

KDM5A controls bone morphogenic protein 2-induced osteogenic differentiation of bone mesenchymal stem cells during osteoporosis

(2016) Chuandong Wang et al.   Cell Death & Disease

Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function

(2016) Violeta I. Gallardo-Montejano et al.   Nature Communications

Osterix represses adipogenesis by negatively regulating PPARγ transcriptional activity

(2016) Younho Han et al.   Scientific Reports

Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoblasts and Adipocytes and its Role in Treatment of Osteoporosis

(2016) Cheng Wang et al.   MEDICAL SCIENCE MONITOR

The Histone Methyltransferase Gene Absent, Small, or Homeotic Discs-1 Like Is Required for Normal Hox Gene Expression and Fertility in Mice1

(2015) Michelle L. Brinkmeier et al.   BIOLOGY OF REPRODUCTION

The nanoscale geometry of TiO2 nanotubes influences the osteogenic differentiation of human adipose-derived stem cells by modulating H3K4 trimethylation

(2015) Longwei Lv et al.   BIOMATERIALS

Trithorax and Polycomb group-dependent regulation: a tale of opposing activities

(2015) S. J. Geisler et al.   DEVELOPMENT

The interplay of histone modifications - writers that read

(2015) T. Zhang et al.   EMBO REPORTS

Histone methylation patterns in astrocytes are influenced by age following ischemia

(2015) Nioka C Chisholm et al.   Epigenetics

Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes

(2015) Yonghui Jin et al.   PLoS One

Reprogramming of Polycomb-Mediated Gene Silencing in Embryonic Stem Cells by the miR-290 Family and the Methyltransferase Ash1l

(2015) Chryssa Kanellopoulou et al.   Stem Cell Reports

Emodin enhances osteogenesis and inhibits adipogenesis

(2014) Feng Yang et al.   BMC Complementary and Alternative Medicine

The SUMO-Specific Isopeptidase SENP3 Regulates MLL1/MLL2 Methyltransferase Complexes and Controls Osteogenic Differentiation

(2014) Arnab Nayak et al.   MOLECULAR CELL

The Regulatory Landscape of Osteogenic Differentiation

(2014) Anne-Mari Håkelien et al.   STEM CELLS

Transcriptional and epigenetic regulation of PPARγ expression during adipogenesis

(2014) Ji-Eun Lee et al.   Cell and Bioscience

Lipin1 regulates PPARγ transcriptional activity

(2013) Hee Eun Kim et al.   BIOCHEMICAL JOURNAL

Histone Methyltransferase Ash1l Suppresses Interleukin-6 Production and Inflammatory Autoimmune Diseases by Inducing the Ubiquitin-Editing Enzyme A20

(2013) Meng Xia et al.   IMMUNITY

Osteopetrosis: genetics, treatment and new insights into osteoclast function

(2013) Cristina Sobacchi et al.   Nature Reviews Endocrinology

EZH2andKDM6AAct as an Epigenetic Switch to Regulate Mesenchymal Stem Cell Lineage Specification

(2013) Sarah Hemming et al.   STEM CELLS

Histone H3 lysine 4 methyltransferases and demethylases in self-renewal and differentiation of stem cells

(2013) Bingnan Gu et al.   Cell and Bioscience

Ash1l Methylates Lys36 of Histone H3 Independently of Transcriptional Elongation to Counteract Polycomb Silencing

(2013) Hitomi Miyazaki et al.   PLoS Genetics

Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation

(2012) Maria Jesus Perugorria et al.   HEPATOLOGY

Down-Regulation of Type I Runx2 Mediated by Dexamethasone Is Required for 3T3-L1 Adipogenesis

(2012) You-you Zhang et al.   MOLECULAR ENDOCRINOLOGY

H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence

(2012) A. Chicas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

Dual Function of Histone H3 Lysine 36 Methyltransferase ASH1 in Regulation of Hox Gene Expression

(2011) Yujiro Tanaka et al.   PLoS One

Inhibition of Osteogenic Differentiation of Human Adipose-Derived Stromal Cells by Retinoblastoma Binding Protein 2 Repression of RUNX2-Activated Transcription

(2011) Wenshu Ge et al.   STEM CELLS

Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: Cross talk with the osteoblastogenic program

(2008) S. Muruganandan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES