COVID-19 and metabolic disease: mechanisms and clinical management

Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020

(2021) Kathy Leung et al.   Eurosurveillance

COVID-19 and chronic fatigue syndrome: Is the worst yet to come?

(2021) Peter Wostyn   MEDICAL HYPOTHESES

Global pandemics interconnected — obesity, impaired metabolic health and COVID-19

(2021) Norbert Stefan et al.   Nature Reviews Endocrinology

DPP-4 inhibitors and severe course of illness in patients with COVID-19

(2021) Béatrice Bouhanick et al.   THERAPIE

Effectiveness and cost-effectiveness of four different strategies for SARS-CoV-2 surveillance in the general population (CoV-Surv Study): a structured summary of a study protocol for a cluster-randomised, two-factorial controlled trial

(2021) Andreas Deckert et al.   Trials

Increased stress, weight gain and less exercise in relation to glycemic control in people with type 1 and type 2 diabetes during the COVID-19 pandemic

(2021) Merel M Ruissen et al.   BMJ Open Diabetes Research & Care

Association Between DPP-4 Inhibitors and COVID-19 Related Outcomes Among Patients With Type 2 Diabetes

(2021) Yunha Noh et al.   DIABETES CARE

Phenotypic characteristics and prognosis of newly diagnosed diabetes in hospitalized patients with COVID-19: results from the CORONADO study

(2021) Bertrand Cariou et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The impact of COVID‐19 restrictions on accelerometer‐assessed physical activity and sleep in individuals with type 2 diabetes

(2021) Alex V. Rowlands et al.   DIABETIC MEDICINE

The disproportionate excess mortality risk of COVID-19 in younger people with diabetes warrants vaccination prioritisation

(2021) Andrew P. McGovern et al.   DIABETOLOGIA

Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England

(2021) Nicholas G. Davies et al.   SCIENCE

Diabetes, obesity, and insulin resistance in COVID-19: molecular interrelationship and therapeutic implications

(2021) Andrey Santos et al.   Diabetology & Metabolic Syndrome

SARS-CoV-2 infects human pancreatic β-cells and elicits β-cell impairment

(2021) Chien-Ting Wu et al.   Cell Metabolism

Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia

(2021) Stefanie Kreutmair et al.   IMMUNITY

Metabolic dysfunction and immunometabolism in COVID-19 pathophysiology and therapeutics

(2021) Rachael Batabyal et al.   INTERNATIONAL JOURNAL OF OBESITY

Higher infectivity of the SARS‐CoV‐2 new variants is associated with K417N/T, E484K, and N501Y mutants: An insight from structural data

(2021) Abbas Khan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pharmacological management of COVID-19 in type 2 diabetes

(2021) Antonio Ceriello et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Post coronavirus disease mucormycosis: a deadly addition to the pandemic spectrum

(2021) S Sharma et al.   JOURNAL OF LARYNGOLOGY AND OTOLOGY

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

(2021) Obbina Abani et al.   LANCET

High-dimensional characterization of post-acute sequelae of COVID-19

(2021) Ziyad Al-Aly et al.   NATURE

Long COVID — metabolic risk factors and novel therapeutic management

(2021) Kamlesh Khunti et al.   Nature Reviews Endocrinology

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil

(2021) Nuno R. Faria et al.   SCIENCE

Therapeutic Potential of Metformin in COVID-19: Reasoning for Its Protective Role

(2021) Samson Mathews Samuel et al.   TRENDS IN MICROBIOLOGY

A systematic review and meta-analysis of geographic differences in comorbidities and associated severity and mortality among individuals with COVID-19

(2021) Bhaskar Thakur et al.   Scientific Reports

Post-covid syndrome in individuals admitted to hospital with covid-19: retrospective cohort study

(2021) Daniel Ayoubkhani et al.   BMJ-British Medical Journal

Prescription of glucose-lowering therapies and risk of COVID-19 mortality in people with type 2 diabetes: a nationwide observational study in England

(2021) Kamlesh Khunti et al.   Lancet Diabetes & Endocrinology

Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

(2021) Sanjay Ramakrishnan et al.   Lancet Respiratory Medicine

Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19

(2021) Sang Youl Rhee et al.   Diabetes & Metabolism Journal

Covid-19 lock down stress and type 1 diabetes mellitus - analysis of crisis psychological intervention (Preprint)

(2021) Katarzyna Cyranka et al.   JMIR Mental Health

BNT162b2 vaccine breakthrough: clinical characteristics of 152 fully vaccinated hospitalized COVID-19 patients in Israel

(2021) Tal Brosh-Nissimov et al.   CLINICAL MICROBIOLOGY AND INFECTION

Diabetes, Obesity, COVID-19, Insulin, and Other Antidiabetes Drugs

(2021) Paresh Dandona et al.   DIABETES CARE

Diabetes and COVID-19: Population Impact 18 Months Into the Pandemic

(2021) Edward W. Gregg et al.   DIABETES CARE

Mucormycosis

(2021) Julie M. Steinbrink et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Viral infiltration of pancreatic islets in patients with COVID-19

(2021) Charlotte Steenblock et al.   Nature Communications

Dapagliflozin in patients with cardiometabolic risk factors hospitalised with COVID-19 (DARE-19): a randomised, double-blind, placebo-controlled, phase 3 trial

(2021) Mikhail N Kosiborod et al.   Lancet Diabetes & Endocrinology

Unraveling the Mystery Surrounding Post-Acute Sequelae of COVID-19

(2021) Rakhee K. Ramakrishnan et al.   Frontiers in Immunology

Experiences, opinions and expectations of health care providers towards an intensive care unit follow-up clinic: Qualitative study and online survey

(2021) Magdalena Rohr et al.   Intensive and Critical Care Nursing

Long-Term Outcomes of Patients with Coronavirus Disease 2019 at One Year after Hospital Discharge

(2021) Modesto M. Maestre-Muñiz et al.   Journal of Clinical Medicine

Adhering to COVID‐19 health guidelines: Examining demographic and psychological predictors of adherence

(2021) Brooklynn Bailey et al.   Applied Psychology-Health and Well Being

Stress and Physical Inactivity: Two Explosive Ingredients for the Heart in COVID-19 Pandemic Times

(2021) Olívia Moraes Ruberti et al.   CURRENT CARDIOLOGY REVIEWS

Intratracheal GLP-1 receptor agonist treatment up-regulates mucin via p38 and exacerbates emphysematous phenotype in mucus hypersecretory obstructive lung diseases

(2020) Hirofumi Nohara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

COVID-19 presenting as stroke

(2020) Akshay Avula et al.   BRAIN BEHAVIOR AND IMMUNITY

The Stanford Hall consensus statement for post-COVID-19 rehabilitation

(2020) Robert M Barker-Davies et al.   BRITISH JOURNAL OF SPORTS MEDICINE

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes

(2020) Lihua Zhu et al.   Cell Metabolism

Association of Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers with Mortality Among Patients With Hypertension Hospitalized With COVID-19

(2020) Peng Zhang et al.   CIRCULATION RESEARCH

COVID-19 and the Heart

(2020) Akbarshakh Akhmerov et al.   CIRCULATION RESEARCH

ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection

(2020) Furong Liu et al.   Clinical Gastroenterology and Hepatology

Negative impact of hyperglycaemia on tocilizumab therapy in Covid-19 patients

(2020) R. Marfella et al.   DIABETES & METABOLISM

COVID ‐19 infection may cause ketosis and ketoacidosis

(2020) Juyi Li et al.   DIABETES OBESITY & METABOLISM

Prevention and management of COVID-19 among patients with diabetes: an appraisal of the literature

(2020) Prasad Katulanda et al.   DIABETOLOGIA

Coronavirus Infections and Type 2 Diabetes—Shared Pathways with Therapeutic Implications

(2020) Daniel J Drucker   ENDOCRINE REVIEWS

Obesity could shift severe COVID-19 disease to younger ages

(2020) David A Kass et al.   LANCET

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis

(2020) Charlotte Steenblock et al.   MOLECULAR PSYCHIATRY

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19

(2020) Giuseppe Mancia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig

(2020) Changhai Lei et al.   Nature Communications

Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?

(2020) Lei Fang et al.   Lancet Respiratory Medicine

Association of Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Testing Positive for Coronavirus Disease 2019 (COVID-19)

(2020) Neil Mehta et al.   JAMA Cardiology

Why inequality could spread COVID-19

(2020) Faheem Ahmed et al.   Lancet Public Health

Newly diagnosed diabetes and diabetic ketoacidosis precipitated by COVID-19 infection

(2020) Ashley I. Heaney et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Metformin and COVID-19: From cellular mechanisms to reduced mortality

(2020) A.J. Scheen   DIABETES & METABOLISM

Prevalence of co‐morbidities and their association with mortality in patients with COVID ‐19: A systematic review and meta‐analysis

(2020) Awadhesh K. Singh et al.   DIABETES OBESITY & METABOLISM

Ketoacidosis in Children and Adolescents With Newly Diagnosed Type 1 Diabetes During the COVID-19 Pandemic in Germany

(2020) Clemens Kamrath et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

New-Onset Diabetes in Covid-19

(2020) Francesco Rubino et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Practical recommendations for the management of diabetes in patients with COVID-19

(2020) Stefan R Bornstein et al.   Lancet Diabetes & Endocrinology

COVID-19 in people with diabetes: understanding the reasons for worse outcomes

(2020) Matteo Apicella et al.   Lancet Diabetes & Endocrinology

Causes, consequences, and treatment of metabolically unhealthy fat distribution

(2020) Norbert Stefan   Lancet Diabetes & Endocrinology

Use of glucocorticoids in patients with adrenal insufficiency and COVID-19 infection

(2020) Andrea M Isidori et al.   Lancet Diabetes & Endocrinology

Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study

(2020) Andrew Clark et al.   Lancet Global Health

The Plasmatic Aldosterone and C-Reactive Protein Levels, and the Severity of Covid-19: The Dyhor-19 Study

(2020) Orianne Villard et al.   Journal of Clinical Medicine

A systematic review and meta-analysis to evaluate the clinical outcomes in COVID-19 patients on angiotensin-converting enzyme inhibitors or angiotensin receptor blockers

(2020) Abhinav Grover et al.   European Heart Journal-Cardiovascular Pharmacotherapy

The MERS-CoV Receptor DPP4 as a Candidate Binding Target of the SARS-CoV-2 Spike

(2020) Yu Li et al.   iScience

Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection

(2020) Jin Wei et al.   CELL

Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes

(2020) Xu Cheng et al.   Cell Metabolism

Sitagliptin Treatment at the Time of Hospitalization Was Associated With Reduced Mortality in Patients With Type 2 Diabetes and COVID-19: A Multicenter, Case-Control, Retrospective, Observational Study

(2020) Sebastiano Bruno Solerte et al.   DIABETES CARE

Time in Range in Relation to All-Cause and Cardiovascular Mortality in Patients With Type 2 Diabetes: A Prospective Cohort Study

(2020) Jingyi Lu et al.   DIABETES CARE

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

(2020) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Anti-inflammatory properties of antidiabetic drugs: A “promised land” in the COVID-19 era?

(2020) Niki Katsiki et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Mortality risk with preadmission metformin use in patients with COVID‐19 and diabetes: A meta‐analysis

(2020) Chia Siang Kow et al.   JOURNAL OF MEDICAL VIROLOGY

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

(2020) Ludovico Cantuti-Castelvetri et al.   SCIENCE

Prevalence of people at risk of developing type 2 diabetes mellitus and the involvement of community pharmacies in a national screening campaign: a pioneer action in Brazil

(2020) Cassyano J. Correr et al.   Diabetology & Metabolic Syndrome

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

(2020) Rajendra Karki et al.   CELL

Insulin Treatment Is Associated with Increased Mortality in Patients with COVID-19 and Type 2 Diabetes

(2020) Bo Yu et al.   Cell Metabolism

Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19

(2020) Irina Kusmartseva et al.   Cell Metabolism

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells

(2020) Katie C. Coate et al.   Cell Metabolism

COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic’s Impact in Type 1 and Type 2 Diabetes

(2020) Justin M. Gregory et al.   DIABETES CARE

Association Between Achieving Inpatient Glycemic Control and Clinical Outcomes in Hospitalized Patients With COVID-19: A Multicenter, Retrospective Hospital-Based Analysis

(2020) David C. Klonoff et al.   DIABETES CARE

Change in glucose‐lowering medication regimens in individuals with type 2 diabetes mellitus during the COVID ‐19 pandemic in Germany

(2020) Louis Jacob et al.   DIABETES OBESITY & METABOLISM

Use of MyDesmond digital education programme to support self‐management in people with type 2 diabetes during the COVID‐19 pandemic

(2020) Lauren M. Quinn et al.   DIABETIC MEDICINE

A post COVID‐19 ‘Marshall Plan’ for type 2 diabetes

(2020) John R. Petrie et al.   DIABETIC MEDICINE

New onset diabetes with diabetic ketoacidosis in a child with multisystem inflammatory syndrome due to COVID-19

(2020) Monica N. Naguib et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

(2020) Juliana C N Chan et al.   LANCET

Risks of and risk factors for COVID-19 disease in people with diabetes: a cohort study of the total population of Scotland

(2020) Stuart J McGurnaghan et al.   Lancet Diabetes & Endocrinology

Diabetes-related Amputations During COVID-19: A Pandemic Within a Pandemic

(2020) Lee C. Rogers et al.   JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION

The adrenal gland in stress – Adaptation on a cellular level

(2019) Ilona Berger et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

What should governments be doing to prevent diabetes throughout the life course?

(2019) Patrick Timpel et al.   DIABETOLOGIA

Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA

(2019) Jonathan L.S. Esguerra et al.   Molecular Metabolism

Blood Sugar Regulation for Cardiovascular Health Promotion and Disease Prevention

(2018) Peter E.H. Schwarz et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Macrophage function in obesity-induced inflammation and insulin resistance

(2017) Mario A. R. Lauterbach et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The vasoprotective axes of the renin-angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases

(2017) Xiao C. Li et al.   PHARMACOLOGICAL RESEARCH

Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation

(2015) Sardar Sindhu et al.   PLoS One

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

(2014) Nathalie Esser et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Pharmacology, Physiology, and Mechanisms of Action of Dipeptidyl Peptidase-4 Inhibitors

(2014) Erin E. Mulvihill et al.   ENDOCRINE REVIEWS

The European perspective of diabetes prevention: The need for individualization of diabetes prevention

(2014) G. Müller et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Insulin Receptor Signaling in Normal and Insulin-Resistant States

(2014) J. Boucher et al.   Cold Spring Harbor Perspectives in Biology

ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis

(2013) AC Simões e Silva et al.   BRITISH JOURNAL OF PHARMACOLOGY

Twelve-year trends in the prevalence and risk factors of diabetes and prediabetes in Turkish adults

(2013) Ilhan Satman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Glucocorticoid-induced hyperglycemia (糖皮质激素诱导的高血糖)

(2013) Antonio Perez et al.   Journal of Diabetes

Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study

(2011) Harvey Moldofsky et al.   BMC Neurology

Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes

(2009) Jin-Kui Yang et al.   ACTA DIABETOLOGICA