Unraveling the Mystery Surrounding Post-Acute Sequelae of COVID-19

Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19

(2021) Yun Kit Yeoh et al.   GUT

6-month consequences of COVID-19 in patients discharged from hospital: a cohort study

(2021) Chaolin Huang et al.   LANCET

Long COVID in the skin: a registry analysis of COVID-19 dermatological duration

(2021) Devon E McMahon et al.   LANCET INFECTIOUS DISEASES

Evolution of antibody immunity to SARS-CoV-2

(2021) Christian Gaebler et al.   NATURE

What we know about covid-19 reinfection so far

(2021) Chris Stokel-Walker   BMJ-British Medical Journal

Nucleic Acid-Sensing Pathways During SARS-CoV-2 Infection: Expectations versus Reality

(2021) Bushra Mdkhana et al.   Journal of Inflammation Research

Gastrointestinal sequelae 90 days after discharge for COVID-19

(2021) Jingrong Weng et al.   Lancet Gastroenterology & Hepatology

Toward Understanding COVID-19 Recovery: National Institutes of Health Workshop on Postacute COVID-19

(2021) Andrea M. Lerner et al.   ANNALS OF INTERNAL MEDICINE

Long-term outcomes of patients following hospitalization for coronavirus disease 2019: a prospective observational study

(2021) Yolanda Meije et al.   CLINICAL MICROBIOLOGY AND INFECTION

Four-Month Clinical Status of a Cohort of Patients After Hospitalization for COVID-19

(2021) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Diverse Functional Autoantibodies in Patients with COVID-19

(2021) Eric Y. Wang et al.   NATURE

High-dimensional characterization of post-acute sequelae of COVID-19

(2021) Ziyad Al-Aly et al.   NATURE

Post-acute COVID-19 syndrome

(2021) Ani Nalbandian et al.   NATURE MEDICINE

Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues

(2021) Liguo Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system

(2021) Susanne Rysz et al.   Nature Communications

Autoimmune Encephalitis Presenting With Malignant Catatonia in a 40-Year-Old Male Patient With COVID-19

(2021) Jan Mulder et al.   AMERICAN JOURNAL OF PSYCHIATRY

Presumed Asymptomatic Carrier Transmission of COVID-19

(2020) Yan Bai et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

(2020) Lirong Zou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial Functions in Infection and Immunity

(2020) Varnesh Tiku et al.   TRENDS IN CELL BIOLOGY

Rehabilitation following critical illness in people with COVID-19 infection

(2020) Robert Simpson et al.   AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION

SARS-CoV-2 Shedding from Asymptomatic Patients: Contribution of Potential Extrapulmonary Tissue Reservoirs

(2020) Raj Kalkeri et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

The Stanford Hall consensus statement for post-COVID-19 rehabilitation

(2020) Robert M Barker-Davies et al.   BRITISH JOURNAL OF SPORTS MEDICINE

Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

(2020) Xiao-Hong Yao et al.   CELL RESEARCH

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients

(2020) Hong-Yi Zheng et al.   Cellular & Molecular Immunology

COVID ‐19 infection may cause ketosis and ketoacidosis

(2020) Juyi Li et al.   DIABETES OBESITY & METABOLISM

Coronaviruses and the cardiovascular system: acute and long-term implications

(2020) Tian-Yuan Xiong et al.   EUROPEAN HEART JOURNAL

The Post-COVID-19 Functional Status (PCFS) Scale: a tool to measure functional status over time after COVID-19

(2020) F.A. Klok et al.   EUROPEAN RESPIRATORY JOURNAL

The Time Sequences of Oral and Fecal Viral Shedding of Coronavirus Disease 2019 (COVID-19) Patients

(2020) Fang Zhao et al.   GASTROENTEROLOGY

Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-19)

(2020) Hiroshi Nishiura et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

The many faces of the anti-COVID immune response

(2020) Santosha A. Vardhana et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evaluation of coagulation function by rotation thromboelastometry in critically ill patients with severe COVID-19 pneumonia

(2020) Vittorio Pavoni et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Comparative computational analysis of SARS-CoV-2 nucleocapsid protein epitopes in taxonomically related coronaviruses

(2020) Bruno Tilocca et al.   MICROBES AND INFECTION

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Neurologic Features in Severe SARS-CoV-2 Infection

(2020) Julie Helms et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiorgan and Renal Tropism of SARS-CoV-2

(2020) Victor G. Puelles et al.   NEW ENGLAND JOURNAL OF MEDICINE

Temporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study

(2020) Yuhui Wang et al.   RADIOLOGY

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

(2020) Ling Mao et al.   JAMA Neurology

Prevalence and impact of diabetes among people infected with SARS-CoV-2

(2020) G. P. Fadini et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Bo Diao et al.   Frontiers in Immunology

Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis

(2020) Ren Mao et al.   Lancet Gastroenterology & Hepatology

Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis

(2020) Keshav K. Singh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Characterization of the Inflammatory Response to Severe COVID-19 Illness

(2020) Oliver J McElvaney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Autoantibodies related to systemic autoimmune rheumatic diseases in severely ill patients with COVID-19

(2020) Panayiotis G Vlachoyiannopoulos et al.   ANNALS OF THE RHEUMATIC DISEASES

Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus

(2020) Ying Jie Chee et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19

(2020) Tao Zuo et al.   GUT

Post-Intensive care syndrome and COVID-19: crisis after a crisis?

(2020) Abbis Jaffri et al.   HEART & LUNG

Absent immune response to SARS-CoV-2 in a 3-month recurrence of coronavirus disease 2019 (COVID-19) case

(2020) Guosheng Gao et al.   INFECTION

Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS

(2020) Carlos Ferrando et al.   INTENSIVE CARE MEDICINE

Persistent Symptoms in Patients After Acute COVID-19

(2020) Angelo Carfì et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

COVID-19 and neurological disorders: are neurodegenerative or neuroimmunological diseases more vulnerable?

(2020) Luigi Ferini-Strambi et al.   JOURNAL OF NEUROLOGY

COVID-19–associated acute necrotising encephalopathy successfully treated with steroids and polyvalent immunoglobulin with unusual IgG targeting the cerebral fibre network

(2020) Louis Delamarre et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen

(2020) Santosha A. Vardhana et al.   NATURE IMMUNOLOGY

Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

(2020) Quan-Xin Long et al.   NATURE MEDICINE

Extrapulmonary manifestations of COVID-19

(2020) Aakriti Gupta et al.   NATURE MEDICINE

New-Onset Diabetes in Covid-19

(2020) Francesco Rubino et al.   NEW ENGLAND JOURNAL OF MEDICINE

Are superantigens the cause of cytokine storm and viral sepsis in severe COVID‐19? Observations and hypothesis

(2020) Valeria Scaglioni et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Incidence of thrombotic complications in critically ill ICU patients with COVID-19

(2020) F.A. Klok et al.   THROMBOSIS RESEARCH

Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

(2020) Sara De Biasi et al.   Nature Communications

CT features of COVID-19 patients with two consecutive negative RT-PCR tests after treatment

(2020) Zhao Fu et al.   Scientific Reports

Immediate and long-term consequences of COVID-19 infections for the development of neurological disease

(2020) Michael T. Heneka et al.   Alzheimers Research & Therapy

Management of post-acute covid-19 in primary care

(2020) Trisha Greenhalgh et al.   BMJ-British Medical Journal

Body fluids may contribute to human-to-human transmission of severe acute respiratory syndrome coronavirus 2: evidence and practical experience

(2020) Amir Hossein Mohseni et al.   Chinese Medicine

Management of critically ill patients with COVID-19 in ICU: statement from front-line intensive care experts in Wuhan, China

(2020) You Shang et al.   Annals of Intensive Care

Practical recommendations for the management of diabetes in patients with COVID-19

(2020) Stefan R Bornstein et al.   Lancet Diabetes & Endocrinology

Remodeling of the Immune Response With Aging: Immunosenescence and Its Potential Impact on COVID-19 Immune Response

(2020) Lucas Leite Cunha et al.   Frontiers in Immunology

Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network — United States, March–June 2020

(2020) Mark W. Tenforde et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19)

(2020) Valentina O. Puntmann et al.   JAMA Cardiology

ACE2 imbalance as a key player for the poor outcomes in COVID-19 patients with age-related comorbidities – Role of gut microbiota dysbiosis

(2020) Sofia D. Viana et al.   AGEING RESEARCH REVIEWS

Functional Limitations Post-COVID-19: A Comprehensive Assessment Strategy

(2020) Rodrigo Torres-Castro et al.   ARCHIVOS DE BRONCONEUMOLOGIA

A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model

(2020) Jakob Kreye et al.   CELL

The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19

(2020) Camila Rosat Consiglio et al.   CELL

Innate immunity during SARS‐CoV‐2: evasion strategies and activation trigger hypoxia and vascular damage

(2020) S. Amor et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

As Their Numbers Grow, COVID-19 “Long Haulers” Stump Experts

(2020) Rita Rubin   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Histopathological observations in COVID-19: a systematic review

(2020) Vishwajit Deshmukh et al.   JOURNAL OF CLINICAL PATHOLOGY

COVID-19 and multiorgan failure: A narrative review on potential mechanisms

(2020) Tahmineh Mokhtari et al.   JOURNAL OF MOLECULAR HISTOLOGY

Genomic evidence for reinfection with SARS-CoV-2: a case study

(2020) Richard L Tillett et al.   LANCET INFECTIOUS DISEASES

Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19

(2020) Matthew C. Woodruff et al.   NATURE IMMUNOLOGY

Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation

(2020) Mary Hongying Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

(2020) Paul Bastard et al.   SCIENCE

Covid-19: Hong Kong scientists report first confirmed case of reinfection

(2020) Jane Parry   BMJ-British Medical Journal

Long covid could be four different syndromes, review suggests

(2020) Elisabeth Mahase   BMJ-British Medical Journal

A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome accelerate short- and long-term inflammaging?

(2020) Arsun Bektas et al.   Immunity & Ageing

Cardiovascular Magnetic Resonance Findings in Competitive Athletes Recovering From COVID-19 Infection

(2020) Saurabh Rajpal et al.   JAMA Cardiology

Mitochondrial metabolic manipulation by SARS-CoV-2 in peripheral blood mononuclear cells of patients with COVID-19

(2020) Saima Ajaz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

High frequency of cerebrospinal fluid autoantibodies in COVID-19 patients with neurological symptoms

(2020) Christiana Franke et al.   BRAIN BEHAVIOR AND IMMUNITY

Understanding the outcomes of COVID-19 – does the current model of an acute respiratory infection really fit?

(2020) Peter Simmonds et al.   JOURNAL OF GENERAL VIROLOGY

Prior SARS-CoV-2 infection is associated with protection against symptomatic reinfection

(2020) Aidan T. Hanrath et al.   JOURNAL OF INFECTION

Lung transplantation for patients with severe COVID-19

(2020) Ankit Bharat et al.   Science Translational Medicine

Patient outcomes after hospitalisation with COVID-19 and implications for follow-up: results from a prospective UK cohort

(2020) David T Arnold et al.   THORAX

NICE guideline on long covid

(2020) Manoj Sivan et al.   BMJ-British Medical Journal

Enhanced expression of immune checkpoint receptors during SARS-CoV-2 viral infection

(2020) Narjes Saheb Sharif-Askari et al.   Molecular Therapy-Methods & Clinical Development

Sixty-Day Outcomes Among Patients Hospitalized With COVID-19

(2020) Vineet Chopra et al.   ANNALS OF INTERNAL MEDICINE

Depression as a Mediator of Chronic Fatigue and Post-Traumatic Stress Symptoms in Middle East Respiratory Syndrome Survivors

(2019) So Hee Lee et al.   Psychiatry Investigation

Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)

(2019) Sarah Batawi et al.   Health and Quality of Life Outcomes

Dermal and muscle fibroblasts and skeletal myofibers survive chikungunya virus infection and harbor persistent RNA

(2019) Alissa R. Young et al.   PLoS Pathogens

Enhancing Recovery From Sepsis

(2018) Hallie C. Prescott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)

(2018) Robson Augusto Souza Santos et al.   PHYSIOLOGICAL REVIEWS

Review: Chikungunya Arthritis: Implications of Acute and Chronic Inflammation Mechanisms on Disease Management

(2018) Ali Zaid et al.   Arthritis & Rheumatology

Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

(2018) Tamas Fulop et al.   Frontiers in Immunology

T-Cell Exhaustion in Chronic Infections: Reversing the State of Exhaustion and Reinvigorating Optimal Protective Immune Responses

(2018) Alireza Saeidi et al.   Frontiers in Immunology

Intestinal dysbiosis and probiotic applications in autoimmune diseases

(2017) Gislane Lelis Vilela de Oliveira et al.   IMMUNOLOGY

Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection

(2017) Qi Wu et al.   Scientific Reports

Metabolic features of chronic fatigue syndrome

(2016) Robert K. Naviaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockade of IL-6TransSignaling Attenuates Pulmonary Fibrosis

(2014) Thanh-Thuy T. Le et al.   JOURNAL OF IMMUNOLOGY

SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome

(2014) Chong-Shan Shi et al.   JOURNAL OF IMMUNOLOGY

ACE2 – From the renin–angiotensin system to gut microbiota and malnutrition

(2013) Thomas Perlot et al.   MICROBES AND INFECTION

Tolerance and exhaustion: defining mechanisms of T cell dysfunction

(2013) Andrea Schietinger et al.   TRENDS IN IMMUNOLOGY

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

(2012) Tatsuo Hashimoto et al.   NATURE

Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study

(2011) Harvey Moldofsky et al.   BMC Neurology

Improving long-term outcomes after discharge from intensive care unit

(2011) Dale M. Needham et al.   CRITICAL CARE MEDICINE

Functional Disability 5 Years after Acute Respiratory Distress Syndrome

(2011) Margaret S. Herridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

T-cell exhaustion: characteristics, causes and conversion

(2010) John S. Yi et al.   IMMUNOLOGY

The long-term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status

(2010) Jenny C. NGAI et al.   RESPIROLOGY

Tissue-Specific Amino Acid Transporter Partners ACE2 and Collectrin Differentially Interact With Hartnup Mutations

(2008) Simone M.R. Camargo et al.   GASTROENTEROLOGY