Designer Extracellular Vesicles Modulate Pro‐Neuronal Cell Responses and Improve Intracranial Retention

Extracellular vesicles versus synthetic nanoparticles for drug delivery

(2021) Kenneth W. Witwer et al.   Nature Reviews Materials

Nanotransfection-based vasculogenic cell reprogramming drives functional recovery in a mouse model of ischemic stroke

(2021) Luke R. Lemmerman et al.   Science Advances

Super-Resolution Imaging Using a Novel High-Fidelity Antibody Reveals Close Association of the Neuronal Sodium Channel NaV1.6 with Ryanodine Receptors in Cardiac Muscle

(2020) Heather L. Struckman et al.   MICROSCOPY AND MICROANALYSIS

Extracellular vesicles as drug delivery systems: Why and how?

(2020) Omnia M. Elsharkasy et al.   ADVANCED DRUG DELIVERY REVIEWS

Effects of exosome-mediated delivery of myostatin propeptide on functional recovery of mdx mice

(2020) Ning Ran et al.   BIOMATERIALS

Early Intervention in Ischemic Tissue with Oxygen Nanocarriers Enables Successful Implementation of Restorative Cell Therapies

(2020) Ludmila Diaz-Starokozheva et al.   Cellular and Molecular Bioengineering

Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles

(2020) Julien Saint-Pol et al.   Cells

Bioactive DNA from extracellular vesicles and particles

(2020) Ethan Z. Malkin et al.   Cell Death & Disease

Tangential Flow Filtration, a potential method for the scaled preparation of Extracellular Vesicles

(2019) V. Börger et al.   CYTOTHERAPY

Immunomodulatory properties of MSC-derived exosomes armed with high affinity aptamer toward mylein as a platform for reducing multiple sclerosis clinical score

(2019) Fazileh Hosseini Shamili et al.   JOURNAL OF CONTROLLED RELEASE

Drug Delivery with Extracellular Vesicles: From Imagination to Innovation

(2019) Olivier G. de Jong et al.   ACCOUNTS OF CHEMICAL RESEARCH

Surface modification of gold nanoparticles with neuron-targeted exosome for enhanced blood–brain barrier penetration

(2019) Mattaka Khongkow et al.   Scientific Reports

Systemic delivery of microRNA-21 antisense oligonucleotides to the brain using T7-peptide decorated exosomes

(2019) Gyeungyun Kim et al.   JOURNAL OF CONTROLLED RELEASE

Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

(2018) Tian Tian et al.   BIOMATERIALS

Exosomes and Stem Cells in Degenerative Disease Diagnosis and Therapy

(2018) Yu-Hsun Chang et al.   CELL TRANSPLANTATION

The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage

(2018) Cecilia Wallin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons

(2018) Juan Carlos Polanco et al.   Acta Neuropathologica Communications

Tangential Flow Filtration for Highly Efficient Concentration of Extracellular Vesicles from Large Volumes of Fluid

(2018) Sara Busatto et al.   Cells

Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges

(2017) Ming Ming Wen et al.   JOURNAL OF CONTROLLED RELEASE

Destination Brain: the Past, Present, and Future of Therapeutic Gene Delivery

(2017) Chaitanya R. Joshi et al.   Journal of Neuroimmune Pharmacology

Super-resolution for everybody: An image processing workflow to obtain high-resolution images with a standard confocal microscope

(2017) France Lam et al.   METHODS

Topical tissue nano-transfection mediates non-viral stroma reprogramming and rescue

(2017) Daniel Gallego-Perez et al.   Nature Nanotechnology

Viral effects on the content and function of extracellular vesicles

(2017) Nancy Raab-Traub et al.   NATURE REVIEWS MICROBIOLOGY

White Matter Repair After Extracellular Vesicles Administration in an Experimental Animal Model of Subcortical Stroke

(2017) Laura Otero-Ortega et al.   Scientific Reports

Extracellular Vesicles in Brain Tumors and Neurodegenerative Diseases

(2017) Federica Ciregia et al.   Frontiers in Molecular Neuroscience

Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia

(2017) Jialei Yang et al.   Molecular Therapy-Nucleic Acids

Delivery of Therapeutic Proteins via Extracellular Vesicles: Review and Potential Treatments for Parkinson’s Disease, Glioma, and Schwannoma

(2016) Justin Hall et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles

(2016) Sriram Balusu et al.   EMBO Molecular Medicine

Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer’s and Parkinson’s Disease

(2016) Laura Vella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Critical Role for Ubiquitination in the Endocytosis of Glutamate Receptors

(2016) Ravinder Gulia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes as therapeutics: The implications of molecular composition and exosomal heterogeneity

(2016) Scott W. Ferguson et al.   JOURNAL OF CONTROLLED RELEASE

Deterministic transfection drives efficient nonviral reprogramming and uncovers reprogramming barriers

(2016) Daniel Gallego-Perez et al.   Nanomedicine-Nanotechnology Biology and Medicine

Extracellular vesicles in neurodegenerative disease — pathogenesis to biomarkers

(2016) Alexander G. Thompson et al.   Nature Reviews Neurology

Extracellular vesicles round off communication in the nervous system

(2016) Vivian Budnik et al.   NATURE REVIEWS NEUROSCIENCE

Modulation of tissue tropism and biological activity of exosomes and other extracellular vesicles: New nanotools for cancer treatment

(2016) Sander A.A. Kooijmans et al.   PHARMACOLOGICAL RESEARCH

Cell-specific uptake of mantle cell lymphoma-derived exosomes by malignant and non-malignant B-lymphocytes

(2015) Inbal Hazan-Halevy et al.   CANCER LETTERS

Stem Cell Therapies in Clinical Trials: Progress and Challenges

(2015) Alan Trounson et al.   Cell Stem Cell

Drug and gene delivery across the blood–brain barrier with focused ultrasound

(2015) Kelsie F. Timbie et al.   JOURNAL OF CONTROLLED RELEASE

Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse

(2015) Yuchen Liu et al.   Scientific Reports

Nerve Growth Factor Gene Therapy

(2015) Mark H. Tuszynski et al.   JAMA Neurology

Ex Vivo Gene Therapy Using Patient iPSC-Derived NSCs Reverses Pathology in the Brain of a Homologous Mouse Model

(2015) Tagan A. Griffin et al.   Stem Cell Reports

Microvesicles: What is the Role in Multiple Sclerosis?

(2015) Tiziana Carandini et al.   Frontiers in Neurology

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Exosomes as a Nanodelivery System: a Key to the Future of Neuromedicine?

(2014) Arian Aryani et al.   MOLECULAR NEUROBIOLOGY

Stem cell transplantation for treating stroke: status, trends and development

(2014) Jiajun Chen et al.   Neural Regeneration Research

Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1

(2014) Soham Chanda et al.   Stem Cell Reports

Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies

(2013) Andrew S Lee et al.   NATURE MEDICINE

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles

(2013) Hongqi Xin et al.   STEM CELLS

Extracellular vesicles in physiological and pathological conditions

(2012) Yuana Yuana et al.   BLOOD REVIEWS

Lessons from human teratomas to guide development of safe stem cell therapies

(2012) Justine J Cunningham et al.   NATURE BIOTECHNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Nonviral Direct Conversion of Primary Mouse Embryonic Fibroblasts to Neuronal Cells

(2012) Andrew F Adler et al.   Molecular Therapy-Nucleic Acids

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Direct conversion of human fibroblasts to dopaminergic neurons

(2011) U. Pfisterer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticles Induce Changes of the Electrical Activity of Neuronal Networks on Microelectrode Array Neurochips

(2010) Alexandra Gramowski et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Nonviral Gene Delivery: Principle, Limitations, and Recent Progress

(2009) Mohammed S. Al-Dosari et al.   AAPS Journal

An Oligovascular Niche: Cerebral Endothelial Cells Promote the Survival and Proliferation of Oligodendrocyte Precursor Cells

(2009) K. Arai et al.   JOURNAL OF NEUROSCIENCE

Gene Therapy Using Adeno-Associated Virus Vectors

(2008) S. Daya et al.   CLINICAL MICROBIOLOGY REVIEWS