Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles

Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding

(2020) Jyothi S Akella et al.   eLife

Release and targeting of polycystin-2-carrying ciliary extracellular vesicles

(2020) Juan Wang et al.   CURRENT BIOLOGY

Exploring Key Challenges of Understanding the Pathogenesis of Kidney Disease in Bardet–Biedl Syndrome

(2020) Emanuela Marchese et al.   Kidney International Reports

Cellular signalling by primary cilia in development, organ function and disease

(2019) Zeinab Anvarian et al.   Nature Reviews Nephrology

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

Establishing and regulating the composition of cilia for signal transduction

(2019) Maxence V. Nachury et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Three-dimensional architecture of epithelial primary cilia

(2019) Shufeng Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane retrieval, recycling and release pathways that organise and sculpt the ciliary membrane

(2019) Stephen P Carter et al.   CURRENT OPINION IN CELL BIOLOGY

Cell–cell communication via ciliary extracellular vesicles: clues from model systems

(2018) Juan Wang et al.   Essays in Biochemistry

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Primary Cilium-Mediated Retinal Pigment Epithelium Maturation Is Disrupted in Ciliopathy Patient Cells

(2018) Helen Louise May-Simera et al.   Cell Reports

Bardet–Biedl Syndrome proteins regulate cilia disassembly during tissue maturation

(2018) Sarita Rani Patnaik et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Retromer has a selective function in cargo sorting via endosome transport carriers

(2018) Yi Cui et al.   JOURNAL OF CELL BIOLOGY

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Post-transcriptional control of miRNA biogenesis

(2018) Gracjan Michlewski et al.   RNA

Photoreceptor discs form through peripherin-dependent suppression of ciliary ectosome release

(2017) Raquel Y. Salinas et al.   JOURNAL OF CELL BIOLOGY

Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo

(2017) M Meister et al.   Oncogenesis

Ultra-High Resolution 3D Imaging of Whole Cells

(2016) Fang Huang et al.   CELL

Extracellular Vesicles from Trypanosoma brucei Mediate Virulence Factor Transfer and Cause Host Anemia

(2016) Anthony J. Szempruch et al.   CELL

Comparative Analysis of Ciliary Membranes and Ectosomes

(2016) Huan Long et al.   CURRENT BIOLOGY

Risk Factors for Severe Renal Disease in Bardet–Biedl Syndrome

(2016) Elizabeth Forsythe et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

β-Catenin-Independent Roles of Wnt/LRP6 Signaling

(2016) Sergio P. Acebron et al.   TRENDS IN CELL BIOLOGY

Ciliopathies

(2016) Daniela A. Braun et al.   Cold Spring Harbor Perspectives in Biology

Different populations of Wnt-containing vesicles are individually released from polarized epithelial cells

(2016) Qiuhong Chen et al.   Scientific Reports

Unravelling the pivotal role of Alix in MVB sorting and silencing of the activated EGFR

(2015) Sheng Sun et al.   BIOCHEMICAL JOURNAL

Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis

(2015) Juan Wang et al.   CURRENT BIOLOGY

Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea

(2015) H. L. May-Simera et al.   DEVELOPMENT

Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis

(2015) Julie E. Maguire et al.   MOLECULAR BIOLOGY OF THE CELL

Loss of the BBSome perturbs endocytic trafficking and disrupts virulence ofTrypanosoma brucei

(2015) Gerasimos Langousis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ciliary ectosomes: transmissions from the cell's antenna

(2015) Christopher R. Wood et al.   TRENDS IN CELL BIOLOGY

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

(2015) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors

(2015) Qingwen Xu et al.   Scientific Reports

Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding

(2015) Muqing Cao et al.   eLife

ALG-2 activates the MVB sorting function of ALIX through relieving its intramolecular interaction

(2015) Sheng Sun et al.   Cell Discovery

Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery

(2015) Marine Barbelanne et al.   HUMAN MOLECULAR GENETICS

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Developmental signaling: Does it bridge the gap between cilia dysfunction and renal cystogenesis?

(2014) Pamela V. Tran et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma

(2014) R. Koch et al.   BLOOD

C. elegans Ciliated Sensory Neurons Release Extracellular Vesicles that Function in Animal Communication

(2014) Juan Wang et al.   CURRENT BIOLOGY

AMP kinase (PRKAA1)

(2014) Sukriti Krishan et al.   JOURNAL OF CLINICAL PATHOLOGY

Mitotic Wnt Signaling Promotes Protein Stabilization and Regulates Cell Size

(2014) Sergio P. Acebron et al.   MOLECULAR CELL

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2

(2014) Rania Ghossoub et al.   Nature Communications

Ciliary Secretion: Switching the Cellular Antenna to ‘Transmit’

(2013) Prachee Avasthi et al.   CURRENT BIOLOGY

The Cilium Secretes Bioactive Ectosomes

(2013) Christopher R. Wood et al.   CURRENT BIOLOGY

Bardet–Biedl syndrome proteins control the cilia length through regulation of actin polymerization

(2013) Victor Hernandez-Hernandez et al.   HUMAN MOLECULAR GENETICS

Functional interaction between autophagy and ciliogenesis

(2013) Olatz Pampliega et al.   NATURE

Characterization of the Late Endosomal ESCRT Machinery inTrypanosoma brucei

(2013) Jason S. Silverman et al.   TRAFFIC

Lipids and vesicular transport

(2012) Britta Brügger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

(2012) Valbona Luga et al.   CELL

Bardet–Biedl syndrome

(2012) Elizabeth Forsythe et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

(2012) Qihong Zhang et al.   HUMAN MOLECULAR GENETICS

Mechanism of Evenness Interrupted (Evi)-Exosome Release at Synaptic Boutons

(2012) Kate Koles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

The ciliary pocket: a once-forgotten membrane domain at the base of cilia

(2011) Rania Ghossoub et al.   BIOLOGY OF THE CELL

EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms

(2011) J. M. Schroder et al.   JOURNAL OF CELL SCIENCE

Cobblestone HUVECs: A human model system for studying primary ciliogenesis

(2011) Willie J.C. Geerts et al.   JOURNAL OF STRUCTURAL BIOLOGY

Wnt signalling escapes to cilia

(2011) Rieko Ajima et al.   NATURE CELL BIOLOGY

Subcellular spatial regulation of canonical Wnt signalling at the primary cilium

(2011) Madeline A. Lancaster et al.   NATURE CELL BIOLOGY

Exocytosis and protein secretion in Trypanosoma

(2010) Anne Geiger et al.   BMC MICROBIOLOGY

Wnt Signaling: Multivesicular Bodies Hold GSK3 Captive

(2010) Christof Niehrs et al.   CELL

Wnt Signaling Requires Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes

(2010) Vincent F. Taelman et al.   CELL

Vps35 Mediates Vesicle Transport between the Mitochondria and Peroxisomes

(2010) Emélie Braschi et al.   CURRENT BIOLOGY

Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling

(2010) Arthit Chairoungdua et al.   JOURNAL OF CELL BIOLOGY

The primary cilium at a glance

(2010) P. Satir et al.   JOURNAL OF CELL SCIENCE

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

(2010) A. Molla-Herman et al.   JOURNAL OF CELL SCIENCE

Membrane budding and scission by the ESCRT machinery: it's all in the neck

(2010) James H. Hurley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly

(2010) S. Seo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cystic kidney disease: the role of Wnt signaling

(2010) Madeline A. Lancaster et al.   TRENDS IN MOLECULAR MEDICINE

Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless

(2009) Ceren Korkut et al.   CELL

The ESCRT machinery at a glance

(2009) T. Wollert et al.   JOURNAL OF CELL SCIENCE

Characterization of PKD Protein-Positive Exosome-Like Vesicles

(2009) M. C. Hogan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The trypanosome flagellar pocket

(2009) Mark C. Field et al.   NATURE REVIEWS MICROBIOLOGY

GSK3: a multifaceted kinase in Wnt signaling

(2009) Dianqing Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE