Retromer has a selective function in cargo sorting via endosome transport carriers

Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting

(2018) Marc Lenoir et al.   Nature Communications

Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval

(2018) Jennifer Hirst et al.   PLOS BIOLOGY

Impaired axonal retrograde trafficking of the retromer complex augments lysosomal deficits in Alzheimer’s disease neurons

(2017) Prasad Tammineni et al.   HUMAN MOLECULAR GENETICS

Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport

(2017) Arunas Kvainickas et al.   JOURNAL OF CELL BIOLOGY

Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR

(2017) Boris Simonetti et al.   JOURNAL OF CELL BIOLOGY

Essential and selective role of SNX12 in transport of endocytic and retrograde cargo

(2017) Amulya Priya et al.   JOURNAL OF CELL SCIENCE

Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake

(2017) Srirupa Roy et al.   MOLECULAR CELL

TBC1D23 is a bridging factor for endosomal vesicle capture by golgins at the trans-Golgi

(2017) John J. H. Shin et al.   NATURE CELL BIOLOGY

Retromer and the cation-independent mannose 6-phosphate receptor-Time for a trial separation?

(2017) Matthew N. J. Seaman   TRAFFIC

Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis

(2017) Markus C. Kerr et al.   Nature Communications

Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction

(2017) Cherilyn A Elwell et al.   eLife

Structural Mechanism for Cargo Recognition by the Retromer Complex

(2016) María Lucas et al.   CELL

Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot

(2016) Deborah C.I. Goberdhan et al.   Cell Metabolism

Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity

(2016) Nicholas A. Bright et al.   CURRENT BIOLOGY

Functional characterization of retromer in GLUT4 storage vesicle formation and adipocyte differentiation

(2016) Zhe Yang et al.   FASEB JOURNAL

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Finding the Golgi: Golgin Coiled-Coil Proteins Show the Way

(2016) Alison K. Gillingham et al.   TRENDS IN CELL BIOLOGY

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lrp1/LDL Receptor Play Critical Roles in Mannose 6-Phosphate-Independent Lysosomal Enzyme Targeting

(2015) Sandra Markmann et al.   TRAFFIC

Retromer Ensures the Degradation of Autophagic Cargo by Maintaining Lysosome Function in Drosophila

(2015) Tamás Maruzs et al.   TRAFFIC

Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation

(2014) Ian J. McGough et al.   CURRENT BIOLOGY

Retromer and the dynamin Vps1 cooperate in the retrieval of transmembrane proteins from vacuoles

(2014) H. Arlt et al.   JOURNAL OF CELL SCIENCE

VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease

(2014) Emiko Miura et al.   NEUROBIOLOGY OF DISEASE

The specificity of vesicle traffic to the Golgi is encoded in the golgin coiled-coil proteins

(2014) M. Wong et al.   SCIENCE

Genome-wide RNAi Screen Reveals a Role for Multipass Membrane Proteins in Endosome-to-Golgi Retrieval

(2014) Sophia Y. Breusegem et al.   Cell Reports

The Retromer Complex Is Required for Rhodopsin Recycling and Its Loss Leads to Photoreceptor Degeneration

(2014) Shiuan Wang et al.   PLOS BIOLOGY

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A mechanism for retromer endosomal coat complex assembly with cargo

(2013) M. S. Harrison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Vps35 D620N Mutation Linked to Parkinson's Disease Disrupts the Cargo Sorting Function of Retromer

(2013) Jordan Follett et al.   TRAFFIC

The retromer complex - endosomal protein recycling and beyond

(2012) M. N. J. Seaman   JOURNAL OF CELL SCIENCE

Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromer

(2012) Da Jia et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of Alzheimer disease-associated variants in genes that regulate retromer function

(2012) Badri N. Vardarajan et al.   NEUROBIOLOGY OF AGING

Retromer Guides STxB and CD8-M6PR from Early to Recycling Endosomes, EHD1 Guides STxB from Recycling Endosome to Golgi

(2012) Jenna E. McKenzie et al.   TRAFFIC

Recruitment of the endosomal WASH complex is mediated by the extended ‘tail’ of Fam21 binding to the retromer protein Vps35

(2011) Michael E. Harbour et al.   BIOCHEMICAL JOURNAL

Inhibition of Retromer Activity by Herpesvirus Saimiri Tip Leads to CD4 Downregulation and Efficient T Cell Transformation

(2011) D. Kingston et al.   JOURNAL OF VIROLOGY

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

(2011) Martin Harterink et al.   NATURE CELL BIOLOGY

Vps26A and Vps26B Subunits Define Distinct Retromer Complexes

(2011) Andrea Bugarcic et al.   TRAFFIC

The Golgin Coiled-Coil Proteins of the Golgi Apparatus

(2011) S. Munro   Cold Spring Harbor Perspectives in Biology

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Multisubunit Tethering Complexes and Their Role in Membrane Fusion

(2010) Cornelia Bröcker et al.   CURRENT BIOLOGY

Identification of different itineraries and retromer components for endosome-to-Golgi transport of TGN38 and Shiga toxin

(2010) Zi Zhao Lieu et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

(2010) M. E. Harbour et al.   JOURNAL OF CELL SCIENCE

Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1

(2010) M. Tabuchi et al.   JOURNAL OF CELL SCIENCE

The retromer component SNX6 interacts with dynactin p150Glued and mediates endosome-to-TGN transport

(2009) Zhi Hong et al.   CELL RESEARCH

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

TIP47 functions in the biogenesis of lipid droplets

(2009) Anna V. Bulankina et al.   JOURNAL OF CELL BIOLOGY

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

(2009) M. N. J. Seaman et al.   JOURNAL OF CELL SCIENCE

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7

(2008) Raul Rojas et al.   JOURNAL OF CELL BIOLOGY

The DHR1 Domain of DOCK180 Binds to SNX5 and Regulates Cation-independent Mannose 6-phosphate Receptor Transport

(2008) Shigeo Hara et al.   MOLECULAR BIOLOGY OF THE CELL

Structure of Vps26B and Mapping of its Interaction with the Retromer Protein Complex

(2008) Brett M. Collins et al.   TRAFFIC