A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains

Prokaryote toxin–antitoxin modules: Complex regulation of an unclear function

(2021) Pieter De Bruyn et al.   PROTEIN SCIENCE

RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis

(2021) Tatsuaki Kurata et al.   MOLECULAR CELL

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Type II toxin-antitoxin systems: evolution and revolutions

(2020) N. Fraikin et al.   JOURNAL OF BACTERIOLOGY

Improved protein structure prediction using predicted interresidue orientations

(2020) Jianyi Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A widespread toxin−antitoxin system exploiting growth control via alarmone signaling

(2020) Steffi Jimmy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxin-Antitoxin Gene Pairs Found in Tn3 Family Transposons Appear To Be an Integral Part of the Transposition Module

(2020) Gipsi Lima-Mendez et al.   mBio

A Primary Physiological Role of Toxin/Antitoxin Systems Is Phage Inhibition

(2020) Sooyeon Song et al.   Frontiers in Microbiology

Abortive Infection: Bacterial Suicide as an Antiviral Immune Strategy

(2020) Anna Lopatina et al.   Annual Review of Virology

FlaGs and webFlaGs: discovering novel biology through the analysis of gene neighbourhood conservation

(2020) Chayan Kumar Saha et al.   BIOINFORMATICS

TASmania: A bacterial Toxin-Antitoxin Systems database

(2019) Hatice Akarsu et al.   PLoS Computational Biology

An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp

(2019) Shehryar Ahmad et al.   NATURE

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

(2018) Lukas Zimmermann et al.   JOURNAL OF MOLECULAR BIOLOGY

Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology

(2018) Alexander Harms et al.   MOLECULAR CELL

FIC proteins: from bacteria to humans and back again

(2018) Simon Veyron et al.   Pathogens and Disease

The Pfam protein families database in 2019

(2018) Sara El-Gebali et al.   NUCLEIC ACIDS RESEARCH

Toxins of Prokaryotic Toxin-Antitoxin Systems with Sequence-Specific Endoribonuclease Activity

(2017) Hisako Masuda et al.   Toxins

Prophage-mediated defence against viral attack and viral counter-defence

(2017) Rebekah M. Dedrick et al.   Nature Microbiology

HPLC-based quantification of bacterial housekeeping nucleotides and alarmone messengers ppGpp and pppGpp

(2017) Vallo Varik et al.   Scientific Reports

Structural Determinants for Antitoxin Identity and Insulation of Cross Talk between Homologous Toxin-Antitoxin Systems

(2016) Lauren R. Walling et al.   JOURNAL OF BACTERIOLOGY

The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA

(2016) Gytis Jankevicius et al.   MOLECULAR CELL

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

CDD/SPARCLE: functional classification of proteins via subfamily domain architectures

(2016) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Evolving New Protein-Protein Interaction Specificity through Promiscuous Intermediates

(2015) Christopher D. Aakre et al.   CELL

IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies

(2014) Lam-Tung Nguyen et al.   MOLECULAR BIOLOGY AND EVOLUTION

RalR (a DNase) and RalA (a small RNA) form a type I toxin–antitoxin system in Escherichia coli

(2014) Yunxue Guo et al.   NUCLEIC ACIDS RESEARCH

A Bacterial Toxin Inhibits DNA Replication Elongation through a Direct Interaction with the β Sliding Clamp

(2013) Christopher D. Aakre et al.   MOLECULAR CELL

The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu

(2013) Daniel Castro-Roa et al.   Nature Chemical Biology

Comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes

(2012) Kira S Makarova et al.   Biology Direct

Dmd of bacteriophage T4 functions as an antitoxin against Escherichia coli LsoA and RnlA toxins

(2012) Yuichi Otsuka et al.   MOLECULAR MICROBIOLOGY

A promiscuous antitoxin of bacteriophage T4 ensures successful viral replication

(2012) Francesca L. Short et al.   MOLECULAR MICROBIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

(2011) Raphaël Leplae et al.   NUCLEIC ACIDS RESEARCH

SecB-like chaperone controls a toxin-antitoxin stress-responsive system in Mycobacterium tuberculosis

(2011) P. Bordes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accelerated Profile HMM Searches

(2011) Sean R. Eddy   PLoS Computational Biology

New toxins homologous to ParE belonging to three-component toxin-antitoxin systems in Escherichia coli O157:H7

(2010) Régis Hallez et al.   MOLECULAR MICROBIOLOGY

Characterization of the Interaction and Cross-Regulation of Three Mycobacterium tuberculosis RelBE Modules

(2010) Min Yang et al.   PLoS One

BLAST+: architecture and applications

(2009) Christiam Camacho et al.   BMC BIOINFORMATICS

MqsR, a Crucial Regulator for Quorum Sensing and Biofilm Formation, Is a GCU-specific mRNA Interferase inEscherichia coli

(2009) Yoshihiro Yamaguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY