Ligustilide attenuates ischemic stroke injury by promoting Drp1-mediated mitochondrial fission via activation of AMPK

Ligustilide Attenuates Ischemia Reperfusion-Induced Hippocampal Neuronal Apoptosis via Activating the PI3K/Akt Pathway

(2020) Qian Wu et al.   Frontiers in Pharmacology

Mitochondrial dysfunction in the development and progression of neurodegenerative diseases

(2020) Joseph Johnson et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ligustilide ameliorates the permeability of the blood-brain barrier model in vitro during oxygen-glucose deprivation injury through HIF/VEGF pathway

(2019) Sipeng Wu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Neurological disorders and mitochondria

(2019) J.V. Cabral-Costa et al.   MOLECULAR ASPECTS OF MEDICINE

Mitophagy is activated in brain damage induced by cerebral ischemia and reperfusion via the PINK1/Parkin/p62 signalling pathway

(2018) Rui Lan et al.   BRAIN RESEARCH BULLETIN

Regulating Renewable Energy

(2018) Sarah E. Shires et al.   CIRCULATION RESEARCH

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Focusing on claudin-5: A promising candidate in the regulation of BBB to treat ischemic stroke

(2018) Jianjun Lv et al.   PROGRESS IN NEUROBIOLOGY

13 reasons why the brain is susceptible to oxidative stress

(2018) James Nathan Cobley et al.   Redox Biology

AMPK: Potential Therapeutic Target for Ischemic Stroke

(2018) Shuai Jiang et al.   Theranostics

Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia

(2018) Yueyang Liu et al.   Autophagy

Mitochondria as a therapeutic target for common pathologies

(2018) Michael P. Murphy et al.   NATURE REVIEWS DRUG DISCOVERY

Resveratrol reduces intracellular reactive oxygen species levels by inducing autophagy through the AMPK-mTOR pathway

(2018) Jun Song et al.   Frontiers of Medicine

Drp1 regulates mitochondrial morphology and cell proliferation in cutaneous squamous cell carcinoma

(2017) Shinya Kitamura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Current evidence for AMPK activation involvement on resveratrol-induced neuroprotection in cerebral ischemia

(2017) Narayana Pineda-Ramírez et al.   NUTRITIONAL NEUROSCIENCE

Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster

(2017) Anil Rana et al.   Nature Communications

Neuroprotective Effect of Ligustilide through Induction of α-Secretase Processing of Both APP and Klotho in a Mouse Model of Alzheimer’s Disease

(2017) Xi Kuang et al.   Frontiers in Aging Neuroscience

Hypothermia-induced ischemic tolerance is associated with Drp1 inhibition in cerebral ischemia-reperfusion injury of mice

(2016) Yingying Tang et al.   BRAIN RESEARCH

AMPK Promotes Autophagy by Facilitating Mitochondrial Fission

(2016) Chen-Song Zhang et al.   Cell Metabolism

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE

(2016) Akihiro Shirakabe et al.   CIRCULATION

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

(2016) E. Q. Toyama et al.   SCIENCE

The critical roles of mitophagy in cerebral ischemia

(2016) Yan-Cheng Tang et al.   Protein & Cell

Oxidative phosphorylation revisited

(2015) Sunil Nath et al.   BIOTECHNOLOGY AND BIOENGINEERING

Amelioration of Ischemic Mitochondrial Injury and Bax-Dependent Outer Membrane Permeabilization by Mdivi-1

(2014) Yan-Xin Zhao et al.   CNS Neuroscience & Therapeutics

Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage

(2014) Wei Zuo et al.   NEUROPHARMACOLOGY