Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster
Authors
Keywords
-
Journal
Nature Communications
Volume 8, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-08-31
DOI
10.1038/s41467-017-00525-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Microbial translocation and skeletal muscle in young and old vervet monkeys
- (2016) Kylie Kavanagh et al. AGE
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis
- (2016) Ramesh Kandimalla et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Exercise Promotes Healthy Aging of Skeletal Muscle
- (2016) Gregory D. Cartee et al. Cell Metabolism
- The Mitochondrial Basis of Aging
- (2016) Nuo Sun et al. MOLECULAR CELL
- Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
- (2016) Dongryeol Ryu et al. NATURE MEDICINE
- Two phases of aging separated by the Smurf transition as a public path to death
- (2016) E. Dambroise et al. Scientific Reports
- Intestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary Restriction
- (2016) Sara Gelino et al. PLoS Genetics
- Mitochondria, autophagy and age-associated neurodegenerative diseases: New insights into a complex interplay
- (2015) Eirini Lionaki et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Measuring In Vivo Mitophagy
- (2015) Nuo Sun et al. MOLECULAR CELL
- Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans
- (2015) Konstantinos Palikaras et al. NATURE
- The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
- (2015) Alicia M. Pickrell et al. NEURON
- Healthy aging: The ultimate preventative medicine
- (2015) M. Kaeberlein et al. SCIENCE
- Mitochondrial dysfunction and longevity in animals: Untangling the knot
- (2015) Y. Wang et al. SCIENCE
- Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice
- (2015) Jean-Philippe Leduc-Gaudet et al. Oncotarget
- Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance
- (2014) Lori Buhlman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mitohormesis
- (2014) Jeanho Yun et al. Cell Metabolism
- The interplay between autophagy and mitochondrial dysfunction in oxidative stress-induced cardiac aging and pathology
- (2014) Stephanie E. Wohlgemuth et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Downregulation of E3 Ubiquitin Ligases and Mitophagy-Related Genes in Skeletal Muscle of Physically Inactive, Frail Older Women: A Cross-Sectional Comparison
- (2014) M. J. Drummond et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Mitochondrial fission facilitates mitophagy inSaccharomyces cerevisiae
- (2013) Kai Mao et al. Autophagy
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Muscle Mitohormesis Promotes Longevity via Systemic Repression of Insulin Signaling
- (2013) Edward Owusu-Ansah et al. CELL
- Expression of mitochondrial fission and fusion regulatory proteins in skeletal muscle during chronic use and disuse
- (2013) Sobia Iqbal et al. MUSCLE & NERVE
- Mitonuclear protein imbalance as a conserved longevity mechanism
- (2013) Riekelt H. Houtkooper et al. NATURE
- Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
- (2013) A. Rana et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
- (2013) E. S. Vincow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drosophila ref(2)P is required for the parkin-mediated suppression of mitochondrial dysfunction in pink1 mutants
- (2013) I P de Castro et al. Cell Death & Disease
- Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy
- (2013) Hagai Abeliovich et al. Nature Communications
- Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner
- (2012) Magdalena Frank et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster
- (2012) I Pimenta de Castro et al. CELL DEATH AND DIFFERENTIATION
- The pathways of mitophagy for quality control and clearance of mitochondria
- (2012) G Ashrafi et al. CELL DEATH AND DIFFERENTIATION
- Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo
- (2012) Brian DuBoff et al. NEURON
- Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila
- (2012) M. Rera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Fission, Fusion, and Stress
- (2012) R. J. Youle et al. SCIENCE
- The dynamin-related protein DRP-1 and the insulin signaling pathway cooperate to modulate Caenorhabditis elegans longevity
- (2011) Christine C. Yang et al. AGING CELL
- Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan
- (2011) Pedro Reis-Rodrigues et al. AGING CELL
- Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health
- (2011) David C. Chan Annual Review of Genetics
- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
- (2011) Xinnan Wang et al. CELL
- The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity
- (2011) Jenni Durieux et al. CELL
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog
- (2011) Michael Rera et al. Cell Metabolism
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
- (2011) Nickie C. Chan et al. HUMAN MOLECULAR GENETICS
- Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
- (2011) A. S. Rambold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging
- (2011) D. R. Green et al. SCIENCE
- The Interplay Between Mitochondrial Dynamics and Mitophagy
- (2010) Gilad Twig et al. ANTIOXIDANTS & REDOX SIGNALING
- FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging
- (2010) Fabio Demontis et al. CELL
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
- (2010) Angela C. Poole et al. PLoS One
- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Transient Niche Regulates the Specification of Drosophila Intestinal Stem Cells
- (2010) D. Mathur et al. SCIENCE
- Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans
- (2010) Della C. David et al. PLOS BIOLOGY
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain
- (2009) Jeffrey M. Copeland et al. CURRENT BIOLOGY
- Dynamics and diversity in autophagy mechanisms: lessons from yeast
- (2009) Hitoshi Nakatogawa et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Characterization of theDrosophilaGene-Switch system in aging studies: a cautionary tale
- (2008) Luc Poirier et al. AGING CELL
- The PINK1–Parkin pathway is involved in the regulation of mitochondrial remodeling process
- (2008) Jeehye Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
- (2008) Gilad Twig et al. EMBO JOURNAL
- Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
- (2008) Y. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1/Parkin pathway regulates mitochondrial morphology
- (2008) A. C. Poole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
- (2008) H. Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now