Amelioration of Ischemic Mitochondrial Injury and Bax-Dependent Outer Membrane Permeabilization by Mdivi-1

Nicorandil Inhibits Inflammasome Activation and Toll-Like Receptor-4 Signal Transduction to Protect against Oxygen-Glucose Deprivation-Induced Inflammation in BV-2 Cells

(2013) An-Peng Zhao et al.   CNS Neuroscience & Therapeutics

M9, A Novel Region of Amino-Nogo-A, Attenuates Cerebral Ischemic Injury by Inhibiting NADPH Oxidase-Derived Superoxide Production in Mice

(2013) Fan Guo et al.   CNS Neuroscience & Therapeutics

The Involvement of Programmed Cell Death 5 (PDCD5) in the Regulation of Apoptosis in Cerebral Ischemia/Reperfusion Injury

(2013) Chun-Hua Chen et al.   CNS Neuroscience & Therapeutics

Histone Decacetylase Inhibitors Prevent Mitochondrial Fragmentation and Elicit Early Neuroprotection against MPP+

(2013) Min Zhu et al.   CNS Neuroscience & Therapeutics

Platelet-Derived Microparticles are Implicated in Remote Ischemia Conditioning in a Rat Model of Cerebral Infarction

(2013) Li-Yang Shan et al.   CNS Neuroscience & Therapeutics

The Parkinson's disease-associated genePINK1protects neurons from ischemic damage by decreasing mitochondrial translocation of the fission promoter Drp1

(2013) Yanxin Zhao et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of Drp1 provides neuroprotection in vitro and in vivo

(2012) J Grohm et al.   CELL DEATH AND DIFFERENTIATION

The Neuroprotective Effect of Losartan through Inhibiting AT1/ASK1/MKK4/JNK3 Pathway Following Cerebral I/R in Rat Hippocampal CA1 Region

(2012) Tian-Ling Zhang et al.   CNS Neuroscience & Therapeutics

Ischemic Postconditioning Diminishes Matrix Metalloproteinase 9 Expression and Attenuates Loss of the Extracellular Matrix Proteins in Rats Following Middle Cerebral Artery Occlusion and Reperfusion

(2012) Xiang-Rong Liu et al.   CNS Neuroscience & Therapeutics

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

(2011) Wenjun Song et al.   NATURE MEDICINE

Impairing the Mitochondrial Fission and Fusion Balance: A New Mechanism of Neurodegeneration

(2010) Andrew B. Knott et al.   Annals of the New York Academy of Sciences

Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization

(2010) Sylvie Montessuit et al.   CELL

Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin

(2010) G M Cereghetti et al.   CELL DEATH AND DIFFERENTIATION

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

Effects of Aquaporin-4 on edema formation following intracerebral hemorrhage

(2010) Yuping Tang et al.   EXPERIMENTAL NEUROLOGY

Perturbations in Mitochondrial Dynamics Induced by Human Mutant PINK1 Can Be Rescued by the Mitochondrial Division Inhibitor mdivi-1

(2010) Mei Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial fission/fusion dynamics and apoptosis

(2010) Clare Sheridan et al.   MITOCHONDRION

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death

(2009) Julia Grohm et al.   BRAIN BEHAVIOR AND IMMUNITY

The Protein Therapy of Kallikrein in Cerebral Ischemic Reperfusion Injury

(2009) Y. Tang et al.   CURRENT MEDICINAL CHEMISTRY

Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons

(2009) Takuma Uo et al.   EXPERIMENTAL NEUROLOGY

Mitochondrial reticulum network dynamics in relation to oxidative stress, redox regulation, and hypoxia

(2009) Petr Ježek et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Dynamins at a glance

(2009) J. A. W. Heymann et al.   JOURNAL OF CELL SCIENCE

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

The molecular mechanism and cellular functions of mitochondrial division

(2008) Laura L. Lackner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY