Vitexin restores lung homeostasis by targeting vicious loop between inflammatory aggravation and autophagy mediated via multiple redox cascade and myeloid cells alteration in experimental allergic asthma

Vitex negundo Linn. extract alleviates inflammatory aggravation and lung injury by modulating AMPK/PI3K/Akt/p38-NF-κB and TGF-β/Smad/Bcl2/caspase/LC3 cascade and macrophages activation in murine model of OVA-LPS induced allergic asthma

(2021) Narendra Vijay Tirpude et al.   JOURNAL OF ETHNOPHARMACOLOGY

Vitexin alleviates high-fat diet induced brain oxidative stress and inflammation via anti-oxidant, anti-inflammatory and gut microbiota modulating properties

(2021) Sen Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dapk1 improves inflammation, oxidative stress and autophagy in LPS-induced acute lung injury via p38MAPK/NF-κB signaling pathway

(2020) Tao Li et al.   MOLECULAR IMMUNOLOGY

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2020) Joan B Soriano et al.   Lancet Respiratory Medicine

Complex interplay between autophagy and oxidative stress in the development of pulmonary disease

(2020) Wojciech Ornatowski et al.   Redox Biology

Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-κB and HO-1 signaling pathways in mice

(2020) Di Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Autophagic flux blockage in alveolar epithelial cells is essential in silica nanoparticle-induced pulmonary fibrosis

(2019) Xinyuan Zhao et al.   Cell Death & Disease

The Cytokines of Asthma

(2019) Bart N. Lambrecht et al.   IMMUNITY

Autophagy induces eosinophil extracellular traps formation and allergic airway inflammation in a murine asthma model

(2019) Josiane Silva Silveira et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Berberis lycium fruit extract attenuates oxi-inflammatory stress and promotes mucosal healing by mitigating NF-κB/c-Jun/MAPKs signalling and augmenting splenic Treg proliferation in a murine model of dextran sulphate sodium-induced ulcerative colitis

(2019) Anamika Sharma et al.   EUROPEAN JOURNAL OF NUTRITION

Genipin attenuates mitochondrial-dependent apoptosis, endoplasmic reticulum stress, and inflammation via the PI3K/AKT pathway in acute lung injury

(2019) Xu Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The high and lows of type 2 asthma and mouse models

(2019) Padraic G. Fallon et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Scrophularia buergeriana attenuates allergic inflammation by reducing NF-κB activation

(2019) Na-Rae Shin et al.   PHYTOMEDICINE

Vitexin inhibits inflammation in murine ovalbumin-induced allergic asthma

(2018) Cláudio Luís Venturini et al.   BIOMEDICINE & PHARMACOTHERAPY

Prunus cerasoides fruit extract ameliorates inflammatory stress by modulation of iNOS pathway and Th1/Th2 immune homeostasis in activated murine macrophages and lymphocytes

(2018) Anamika Sharma et al.   INFLAMMOPHARMACOLOGY

Oxidative stress-driven pulmonary inflammation and fibrosis in a mouse model of human ataxia-telangiectasia

(2018) Ruth Duecker et al.   Redox Biology

Carvedilol attenuates liver fibrosis by suppressing autophagy and promoting apoptosis in hepatic stellate cells

(2018) Dongxiao Meng et al.   BIOMEDICINE & PHARMACOTHERAPY

Interleukin-15 Overexpression Protect Mice from the Allergen-Induced Airway Obstruction

(2016) Sathisha Upparahalli Venkateshaiah et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Expression and role of connexin-based gap junctions in pulmonary inflammatory diseases

(2016) Véronique Freund-Michel et al.   PHARMACOLOGY & THERAPEUTICS

Vitexin reduces neutrophil migration to inflammatory focus by down-regulating pro-inflammatory mediators via inhibition of p38, ERK1/2 and JNK pathway

(2016) Suellen Iara Guirra Rosa et al.   PHYTOMEDICINE

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Curcumin attenuates allergic airway inflammation by regulation of CD4+CD25+ regulatory T cells (Tregs)/Th17 balance in ovalbumin-sensitized mice

(2013) Chunhua Ma et al.   FITOTERAPIA

Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy

(2012) H. Maazi et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Vitexin and isovitexin from the Leaves of Ficus deltoidea with in-vivo α-glucosidase inhibition

(2012) C.Y. Choo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Adoptive Transfer of Induced-Treg Cells Effectively Attenuates Murine Airway Allergic Inflammation

(2012) Wei Xu et al.   PLoS One

Autophagy inhibition enhances ursolic acid-induced apoptosis in PC3 cells

(2011) Seoung Woo Shin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The CKLF1-C19 peptide attenuates allergic lung inflammation by inhibiting CCR3- and CCR4-mediated chemotaxis in a mouse model of asthma

(2010) L. Tian et al.   ALLERGY

Respiratory tract allergic disease and atopy: experimental evidence for a fungal infectious etiology

(2010) Paul Porter et al.   MEDICAL MYCOLOGY

Altered lymphocyte trafficking and diminished airway reactivity in transgenic mice expressing human MMP-9 in a mouse model of asthma

(2009) Divya Mehra et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of GATA-3 in Allergic Diseases

(2008) Peter Barnes   CURRENT MOLECULAR MEDICINE