Long non-coding RNAs: novel regulators of cellular physiology and function

Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator

(2021) Lila Allou et al.   NATURE

The imprinted lncRNA Peg13 regulates sexual preference and the sex-specific brain transcriptome in mice

(2021) Maryam Keshavarz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis

(2021) Michio Sato et al.   Nature Communications

The RNA Atlas expands the catalog of human non-coding RNAs

(2021) Lucia Lorenzi et al.   NATURE BIOTECHNOLOGY

Noncoding RNA therapeutics — challenges and potential solutions

(2021) Melanie Winkle et al.   NATURE REVIEWS DRUG DISCOVERY

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

(2020) D. Julia Trembinski et al.   Nature Communications

Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-Mediated Regulation of PDGFRβ

(2020) Christoph M. Zehendner et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Long Noncoding RNAs: Molecular Modalities to Organismal Functions

(2020) John L. Rinn et al.   Annual Review of Biochemistry

Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy

(2020) Janika Viereck et al.   EUROPEAN HEART JOURNAL

Functional annotation of human long noncoding RNAs via molecular phenotyping

(2020) Jordan A. Ramilowski et al.   GENOME RESEARCH

A novel N6-methyladenosine (m6A)-dependent fate decision for the lncRNA THOR

(2020) Hongmei Liu et al.   Cell Death & Disease

Beyond the RNA-dependent function of LncRNA genes

(2020) Tamer Ali et al.   eLife

Gene regulation by long non-coding RNAs and its biological functions

(2020) Luisa Statello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants

(2020) Lianhe Zhao et al.   NUCLEIC ACIDS RESEARCH

Hematopoietic Deficiency of the Long Non-Coding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation

(2019) Sebastian Cremer et al.   CIRCULATION

The Emerging Roles of TERRA in Telomere Maintenance and Genome Stability

(2019) Nicole Bettin et al.   Cells

New Insights into Long Non-Coding RNA MALAT1 in Cancer and Metastasis

(2019) Yutong Sun et al.   Cancers

Aging well with Norad

(2019) Filipa Carvalhal Marques et al.   eLife

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

(2019) Florian Kopp et al.   eLife

Pleiotropic effects of laminar flow and statins depend on the Krüppel-like factor-induced lncRNA MANTIS

(2019) Matthias S Leisegang et al.   EUROPEAN HEART JOURNAL

Krüppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome

(2019) Mi Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sensitive and quantitative probing of pseudouridine modification in mRNA and long non-coding RNA

(2019) Wen Zhang et al.   RNA

Long Noncoding Transcriptome in Chronic Obstructive Pulmonary Disease

(2019) Dinesh Devadoss et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Xist RNA in action: Past, present, and future

(2019) Agnese Loda et al.   PLoS Genetics

The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis

(2019) Jordan P. Lewandowski et al.   Nature Communications

Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19

(2018) Junjie Tony Hua et al.   CELL

Angio-LncRs: LncRNAs that regulate angiogenesis and vascular disease

(2018) Bo Yu et al.   Theranostics

Lnc2Cancer v2.0: updated database of experimentally supported long non-coding RNAs in human cancers

(2018) Yue Gao et al.   NUCLEIC ACIDS RESEARCH

The NANCI–Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis

(2017) Michael J. Herriges et al.   GENES & DEVELOPMENT

Base-Resolution Mapping Reveals Distinct m 1 A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts

(2017) Xiaoyu Li et al.   MOLECULAR CELL

Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks

(2017) Flavia Michelini et al.   NATURE CELL BIOLOGY

The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways

(2017) Kun Zhang et al.   Nature Communications

Role of BACE1 in Alzheimer’s synaptic function

(2017) Brati Das et al.   Translational Neurodegeneration

Architectural RNAs (arcRNAs): A class of long noncoding RNAs that function as the scaffold of nuclear bodies

(2016) Takeshi Chujo et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

H19Long Noncoding RNA Regulates Intestinal Epithelial Barrier Function via MicroRNA 675 by Interacting with RNA-Binding Protein HuR

(2016) Tongtong Zou et al.   MOLECULAR AND CELLULAR BIOLOGY

Long noncoding RNA SPRY4-IT1 regulates intestinal epithelial barrier function by modulating the expression levels of tight junction proteins

(2016) Lan Xiao et al.   MOLECULAR BIOLOGY OF THE CELL

The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA

(2016) Dan Dominissini et al.   NATURE

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

(2016) Jonathan J. Kotzin et al.   NATURE

Long noncoding RNAs in the p53 network

(2016) Ritu Chaudhary et al.   Wiley Interdisciplinary Reviews-RNA

A Micropeptide Encoded by a Putative Long Noncoding RNA Regulates Muscle Performance

(2015) Douglas M. Anderson et al.   CELL

The Long Noncoding RNA Pnky Regulates Neuronal Differentiation of Embryonic and Postnatal Neural Stem Cells

(2015) Alexander D. Ramos et al.   Cell Stem Cell

N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions

(2015) Nian Liu et al.   NATURE

Enhancer RNAs: A Class of Long Noncoding RNAs Synthesized at Enhancers: Figure 1.

(2015) Tae-Kyung Kim et al.   Cold Spring Harbor Perspectives in Biology

Contrasting expression patterns of coding and noncoding parts of the human genome upon oxidative stress

(2015) Antonis Giannakakis et al.   Scientific Reports

Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs

(2015) Ka-Man Venus Lai et al.   PLoS One

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression

(2014) Roberto Ferrarese et al.   JOURNAL OF CLINICAL INVESTIGATION

LincRNA-p21 Activates p21 In cis to Promote Polycomb Target Gene Expression and to Enforce the G1/S Checkpoint

(2014) Nadya Dimitrova et al.   MOLECULAR CELL

An Evolutionarily Conserved Long Noncoding RNA TUNA Controls Pluripotency and Neural Lineage Commitment

(2014) Nianwei Lin et al.   MOLECULAR CELL

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

A long noncoding RNA protects the heart from pathological hypertrophy

(2014) Pei Han et al.   NATURE

The long non-coding RNA Dali is an epigenetic regulator of neural differentiation

(2014) Vladislava Chalei et al.   eLife

The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

(2013) Phillip Grote et al.   DEVELOPMENTAL CELL

The Long Noncoding RNA RMST Interacts with SOX2 to Regulate Neurogenesis

(2013) Shi-Yan Ng et al.   MOLECULAR CELL

Long non-coding RNAs: new players in cell differentiation and development

(2013) Alessandro Fatica et al.   NATURE REVIEWS GENETICS

On the classification of long non-coding RNAs

(2013) Lina Ma et al.   RNA Biology

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

(2013) Martin Sauvageau et al.   eLife

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation

(2012) Farzaneh Modarresi et al.   NATURE BIOTECHNOLOGY

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

(2012) Jeffrey E. Squires et al.   NUCLEIC ACIDS RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

(2011) Tiffany Hung et al.   NATURE GENETICS

Understanding the transcriptome through RNA structure

(2011) Yue Wan et al.   NATURE REVIEWS GENETICS

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression

(2010) Delphine Bernard et al.   EMBO JOURNAL

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

(2008) Mohammad Ali Faghihi et al.   NATURE MEDICINE