The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis

High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity

(2019) Kaia Mattioli et al.   GENOME RESEARCH

LncRNA FIRRE is activated by MYC and promotes the development of diffuse large B-cell lymphoma via Wnt/β-catenin signaling pathway

(2019) Xue Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LncRNA FIRRE/NF-kB feedback loop contributes to OGD/R injury of cerebral microglial cells

(2018) Yunhua Zang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus

(2018) A. Rasim Barutcu et al.   Nature Communications

Circular RNA expression in human hematopoietic cells is widespread and cell-type specific

(2018) Benoit P Nicolet et al.   NUCLEIC ACIDS RESEARCH

Megadomains and superloops form dynamically but are dispensable for X-chromosome inactivation and gene escape

(2018) John E. Froberg et al.   Nature Communications

Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2

(2018) Roland Elling et al.   Cell Reports

The NF-κB–Responsive Long Noncoding RNA FIRRE Regulates Posttranscriptional Regulation of Inflammatory Gene Expression through Interacting with hnRNPU

(2017) Yajing Lu et al.   JOURNAL OF IMMUNOLOGY

Cellular Decision Making by Non-Integrative Processing of TLR Inputs

(2017) Ryan A. Kellogg et al.   Cell Reports

A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation

(2016) Maninjay K. Atianand et al.   CELL

The functions of long noncoding RNAs in development and stem cells

(2016) Rotem Ben-Tov Perry et al.   DEVELOPMENT

Investigating long noncoding RNAs using animal models

(2016) Michael Feyder et al.   JOURNAL OF CLINICAL INVESTIGATION

Unlinking an lncRNA from Its Associated cis Element

(2016) Vikram R. Paralkar et al.   MOLECULAR CELL

Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development

(2016) Kelly M. Anderson et al.   NATURE

Local regulation of gene expression by lncRNA promoters, transcription and splicing

(2016) Jesse M. Engreitz et al.   NATURE

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

(2016) Jonathan J. Kotzin et al.   NATURE

Deletion ofDXZ4on the human inactive X chromosome alters higher-order genome architecture

(2016) Emily M. Darrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function and evolution of local repeats in the Firre locus

(2016) Ezgi Hacisuleyman et al.   Nature Communications

In Vivo Characterization of Linc-p21 Reveals Functional cis -Regulatory DNA Elements

(2016) Abigail F. Groff et al.   Cell Reports

Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers

(2015) Xiaohui Yan et al.   CANCER CELL

Long Non-Coding RNAs Control Hematopoietic Stem Cell Function

(2015) Min Luo et al.   Cell Stem Cell

Regulation of the ESC transcriptome by nuclear long noncoding RNAs

(2015) Jan H. Bergmann et al.   GENOME RESEARCH

DeCoN: Genome-wide Analysis of In Vivo Transcriptional Dynamics during Pyramidal Neuron Fate Selection in Neocortex

(2015) Bradley J. Molyneaux et al.   NEURON

Principles of Long Noncoding RNA Evolution Derived from Direct Comparison of Transcriptomes in 17 Species

(2015) Hadas Hezroni et al.   Cell Reports

The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation

(2015) Fan Yang et al.   GENOME BIOLOGY

Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis

(2014) Nina Cabezas-Wallscheid et al.   Cell Stem Cell

Xq26.1-26.2 gain identified on array comparative genomic hybridization in bilateral periventricular nodular heterotopia with overlying polymicrogyria

(2014) Yu Abe et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre

(2014) Ezgi Hacisuleyman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA and dynamic nuclear organization

(2014) J. Rinn et al.   SCIENCE

Considerations when investigating lncRNA function in vivo

(2014) Andrew R Bassett et al.   eLife

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Imprinted Igf2r silencing depends on continuous Airn lncRNA expression and is not restricted to a developmental window

(2013) F. Santoro et al.   DEVELOPMENT

Nitric oxide production by endotoxin preparations in TLR4-deficient mice

(2013) Anje Cauwels et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Long noncoding RNAs regulate adipogenesis

(2013) Lei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

(2013) Martin Sauvageau et al.   eLife

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

The macrosatellite DXZ4 mediates CTCF-dependent long-range intrachromosomal interactions on the human inactive X chromosome

(2012) Andrea H. Horakova et al.   HUMAN MOLECULAR GENETICS

Loss of the abundant nuclear non-coding RNAMALAT1is compatible with life and development

(2012) Moritz Eißmann et al.   RNA Biology

Airn Transcriptional Overlap, But Not Its lncRNA Products, Induces Imprinted Igf2r Silencing

(2012) P. A. Latos et al.   SCIENCE

The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult

(2012) Bin Zhang et al.   Cell Reports

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

Global survey of escape from X inactivation by RNA-sequencing in mouse

(2010) F. Yang et al.   GENOME RESEARCH

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

fdrtool: a versatile R package for estimating local and tail area-based false discovery rates

(2008) K. Strimmer   BIOINFORMATICS