A novel N6-methyladenosine (m6A)-dependent fate decision for the lncRNA THOR

The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation

(2020) Tao Liu et al.   NUCLEIC ACIDS RESEARCH

m6A-binding proteins: the emerging crucial performers in epigenetics

(2020) Yanchun Zhao et al.   Journal of Hematology & Oncology

m6A mRNA Destiny: Chained to the rhYTHm by the YTH-Containing Proteins

(2019) Ditipriya Hazra et al.   Genes

Functions of RNA N6-methyladenosine modification in cancer progression

(2019) Bing Chen et al.   MOLECULAR BIOLOGY REPORTS

Functions of RNA N6-methyladenosine modification in cancer progression

(2019) Bing Chen et al.   MOLECULAR BIOLOGY REPORTS

CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis

(2019) Juan Liu et al.   IMMUNITY

The role of m6A RNA methylation in cancer

(2019) Ting Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers

(2019) Hailing Shi et al.   MOLECULAR CELL

m6A enhances the phase separation potential of mRNA

(2019) Ryan J. Ries et al.   NATURE

Interplay Between N6-Methyladenosine (m6A) and Non-coding RNAs in Cell Development and Cancer

(2019) Francesco Fazi et al.   Frontiers in Cell and Developmental Biology

LncRNA THOR promotes tongue squamous cell carcinomas by stabilizing IGF2BP1 downstream targets

(2019) Haojie Yang et al.   BIOCHIMIE

LncRNA THOR promotes human renal cell carcinoma cell growth

(2018) Xue-ting Ye et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long non-coding RNA THOR promotes human osteosarcoma cell growth in vitro and in vivo

(2018) Wangzhen Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation

(2018) Yuan He et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9

(2018) Tingting Sui et al.   Disease Models & Mechanisms

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction

(2018) Luke W Koblan et al.   NATURE BIOTECHNOLOGY

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

(2018) Huilin Huang et al.   NATURE CELL BIOLOGY

N 6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential

(2018) Dandan Yang et al.   NUCLEIC ACIDS RESEARCH

Mutations in Cytosine-5 tRNA Methyltransferases Impact Mobile Element Expression and Genome Stability at Specific DNA Repeats

(2018) Bianca Genenncher et al.   Cell Reports

ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2

(2018) Devanshi Jain et al.   eLife

LncRNA THOR increases the stemness of gastric cancer cells via enhancing SOX9 mRNA stability

(2018) Hu Song et al.   BIOMEDICINE & PHARMACOTHERAPY

Long non-coding RNA THOR promotes cell proliferation and metastasis in hepatocellular carcinoma

(2018) Zhangjun Cheng et al.   GENE

Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation

(2018) Xiang Zhong et al.   Cell Reports

Long non-coding RNA THOR promotes liver cancer stem cells expansion via β-catenin pathway

(2018) Zhangjun Cheng et al.   GENE

Triptonide inhibits human nasopharyngeal carcinoma cell growth via disrupting Lnc-RNA THOR-IGF2BP1 signaling

(2018) Shu-sheng Wang et al.   CANCER LETTERS

m 6 A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover

(2017) Shengdong Ke et al.   GENES & DEVELOPMENT

Regulation of m 6 A Transcripts by the 3ʹ→5ʹ RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline

(2017) Magdalena Natalia Wojtas et al.   MOLECULAR CELL

The RNA m 6 A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence

(2017) Ivayla Ivanova et al.   MOLECULAR CELL

RNA m6A methylation regulates the ultraviolet-induced DNA damage response

(2017) Yang Xiang et al.   NATURE

Evidence for rRNA 2′-O-methylation plasticity: Control of intrinsic translational capabilities of human ribosomes

(2017) Jenny Erales et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

(2016) Katherine E. Sloan et al.   RNA Biology

m6A: Signaling for mRNA splicing

(2016) Samir Adhikari et al.   RNA Biology

HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events

(2015) Claudio R. Alarcón et al.   CELL

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency

(2015) Tong Chen et al.   Cell Stem Cell

N 6-methyladenosine modification in mRNA: machinery, function and implications for health and diseases

(2015) Arpita Maity et al.   FEBS Journal

Structural Basis for the Discriminative Recognition ofN6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins

(2015) Chao Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions

(2015) Nian Liu et al.   NATURE

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

A DNAzyme requiring two different metal ions at two distinct sites

(2015) Wenhu Zhou et al.   NUCLEIC ACIDS RESEARCH

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

The Landscape of long noncoding RNA classification

(2015) Georges St. Laurent et al.   TRENDS IN GENETICS

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

(2014) Xiao-Li Ping et al.   CELL RESEARCH

Structure of the YTH domain of human YTHDF2 in complex with an m6A mononucleotide reveals an aromatic cage for m6A recognition

(2014) Fudong Li et al.   CELL RESEARCH

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders

(2014) S. Blanco et al.   EMBO JOURNAL

Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain

(2014) Chao Xu et al.   Nature Chemical Biology

High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis

(2013) Schraga Schwartz et al.   CELL

lincRNAs: Genomics, Evolution, and Mechanisms

(2013) Igor Ulitsky et al.   CELL

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

N6-methyl-adenosine modification in messenger and long non-coding RNA

(2013) Tao Pan   TRENDS IN BIOCHEMICAL SCIENCES

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Transfer RNA modifications: nature's combinatorial chemistry playground

(2012) Jane E. Jackman et al.   Wiley Interdisciplinary Reviews-RNA

The Emergence of lncRNAs in Cancer Biology

(2011) J. R. Prensner et al.   Cancer Discovery

Grand Challenge Commentary: RNA epigenetics?

(2010) Chuan He   Nature Chemical Biology

Spliceosomal snRNA modifications and their function

(2010) John Karijolich et al.   RNA Biology