Krüppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome

High bone mass in adults

(2018) Julien Paccou et al.   JOINT BONE SPINE

Targeting skeletal endothelium to ameliorate bone loss

(2018) Ren Xu et al.   NATURE MEDICINE

Improving drug adherence in osteoporosis: an update on more recent studies

(2018) Ayesha Jaleel et al.   Therapeutic Advances in Musculoskeletal Disease

Glucose metabolism induced by Bmp signaling is essential for murine skeletal development

(2018) Seung-Yon Lee et al.   Nature Communications

Reg Gene Expression in Periosteum after Fracture and Its In Vitro Induction Triggered by IL-6

(2017) Yasuaki Tohma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Krüppel-like factors compete for promoters and enhancers to fine-tune transcription

(2017) Melissa D. Ilsley et al.   NUCLEIC ACIDS RESEARCH

Bone Cell Bioenergetics and Skeletal Energy Homeostasis

(2017) Ryan C. Riddle et al.   PHYSIOLOGICAL REVIEWS

Human type H vessels are a sensitive biomarker of bone mass

(2017) Liang Wang et al.   Cell Death & Disease

MiR-497∼195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1α activity

(2017) Mi Yang et al.   Nature Communications

Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth

(2017) Guangxu He et al.   Bone Research

Unintended targeting of Dmp1-Cre reveals a critical role for Bmpr1a signaling in the gastrointestinal mesenchyme of adult mice

(2017) Joohyun Lim et al.   Bone Research

Regulation of Hematopoiesis and Osteogenesis by Blood Vessel–Derived Signals

(2016) Saravana K. Ramasamy et al.   Annual Review of Cell and Developmental Biology

Wnt signaling and cellular metabolism in osteoblasts

(2016) Courtney M. Karner et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Angiocrine functions of organ-specific endothelial cells

(2016) Shahin Rafii et al.   NATURE

Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement

(2016) Jawed A. Siddiqui et al.   PHYSIOLOGY

Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone

(2016) Bin Huang et al.   Nature Communications

Ophiopogonin D: A new herbal agent against osteoporosis

(2015) Qiang Huang et al.   BONE

Vascular endothelial growth factor signaling affects both angiogenesis and osteogenesis during the development of scleral ossicles

(2015) James Jabalee et al.   DEVELOPMENTAL BIOLOGY

Phosphorylation of Krüppel-like Factor 3 (KLF3/BKLF) and C-terminal Binding Protein 2 (CtBP2) by Homeodomain-interacting Protein Kinase 2 (HIPK2) Modulates KLF3 DNA Binding and Activity

(2015) Vitri Dewi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone remodeling in the context of cellular and systemic regulation: the role of osteocytes and the nervous system

(2015) Tadeusz Niedźwiedzki et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Sample preparation for high-resolution 3D confocal imaging of mouse skeletal tissue

(2015) Anjali P Kusumbe et al.   Nature Protocols

Regulation of tissue morphogenesis by endothelial cell-derived signals

(2015) Saravana K. Ramasamy et al.   TRENDS IN CELL BIOLOGY

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

(2014) Anjali P. Kusumbe et al.   NATURE

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

(2014) Saravana K. Ramasamy et al.   NATURE

PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis

(2014) Hui Xie et al.   NATURE MEDICINE

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Development of the Endochondral Skeleton

(2013) F. Long et al.   Cold Spring Harbor Perspectives in Biology

ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice

(2013) Lois Kelsey et al.   PLoS Genetics

Estrogen and the skeleton

(2012) Sundeep Khosla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The mammalian zinc finger transcription factor Krüppel-like factor 3 (KLF3/BKLF)

(2011) Richard C.M. Pearson et al.   IUBMB LIFE

Bone Overgrowth-associated Mutations in theLRP4Gene Impair Sclerostin Facilitator Function

(2011) Olivier Leupin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

The holy grail of high bone mass

(2011) Lynda Bonewald   NATURE MEDICINE

Building strong bones: molecular regulation of the osteoblast lineage

(2011) Fanxin Long   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons

(2010) F. Oury et al.   GENES & DEVELOPMENT

KLF3 Regulates Muscle-Specific Gene Expression and Synergizes with Serum Response Factor on KLF Binding Sites

(2010) C. L. Himeda et al.   MOLECULAR AND CELLULAR BIOLOGY

Osteocyte Wnt/ -Catenin Signaling Is Required for Normal Bone Homeostasis

(2010) I. Kramer et al.   MOLECULAR AND CELLULAR BIOLOGY

Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

(2008) Vijay K. Yadav et al.   CELL

Targeted Disruption of the Basic Kruppel-Like Factor Gene (Klf3) Reveals a Role in Adipogenesis

(2008) N. Sue et al.   MOLECULAR AND CELLULAR BIOLOGY