Microglia Polarization from M1 toward M2 Phenotype Is Promoted by Astragalus Polysaccharides Mediated through Inhibition of miR-155 in Experimental Autoimmune Encephalomyelitis

Bu Shen Yi Sui Capsule Alleviates Neuroinflammation and Demyelination by Promoting Microglia toward M2 Polarization, Which Correlates with Changes in miR-124 and miR-155 in Experimental Autoimmune Encephalomyelitis

(2021) Zheng Zha et al.   Oxidative Medicine and Cellular Longevity

Remyelination is enhanced by Astragalus polysaccharides through inducing the differentiation of oligodendrocytes from neural stem cells in cuprizone model of demyelination

(2021) Ni Ye et al.   BRAIN RESEARCH

Methylprednisolone Induces Neuro-Protective Effects via the Inhibition of A1 Astrocyte Activation in Traumatic Spinal Cord Injury Mouse Models

(2021) Hong-jun Zou et al.   Frontiers in Neuroscience

Apigenin Regulates Activation of Microglia and Counteracts Retinal Degeneration

(2020) Onuma Chumsakul et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte

(2020) Min Liu et al.   Journal of Neuroinflammation

Estrogen Attenuates Traumatic Brain Injury by Inhibiting the Activation of Microglia and Astrocyte-Mediated Neuroinflammatory Responses

(2020) Jin Wang et al.   MOLECULAR NEUROBIOLOGY

Quality Control of Radix Astragali (The Root of Astragalus membranaceus var. mongholicus) Along Its Value Chains

(2020) Yaqiong Bi et al.   Frontiers in Pharmacology

Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures

(2019) Bei Zhang et al.   Frontiers in Cellular Neuroscience

The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration

(2019) Jared T. Hinkle et al.   MOVEMENT DISORDERS

The PD-1/PD-Ls pathway is up-regulated during the suppression of experimental autoimmune encephalomyelitis treated by Astragalus polysaccharides

(2019) Yu Sun et al.   JOURNAL OF NEUROIMMUNOLOGY

Dendrobium officinale Polysaccharides Inhibit 1-Methyl-2-Nitro-1-Nitrosoguanidine Induced Precancerous Lesions of Gastric Cancer in Rats through Regulating Wnt/β-Catenin Pathway and Altering Serum Endogenous Metabolites

(2019) Yi Zhao et al.   MOLECULES

Microglia Biology: One Century of Evolving Concepts

(2019) Marco Prinz et al.   CELL

Hypolipidemic effect of polysaccharides from Fortunella margarita (Lour.) Swingle in hyperlipidemic rats

(2019) Hongliang Zeng et al.   FOOD AND CHEMICAL TOXICOLOGY

Purification, structural elucidation and anti-inflammatory activity in vitro of polysaccharides from Smilax china L.

(2019) Yu Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Custom-Made Ceria Nanoparticles Show a Neuroprotective Effect by Modulating Phenotypic Polarization of the Microglia

(2018) Feng Zeng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibition of miR-155 Limits Neuroinflammation and Improves Functional Recovery After Experimental Traumatic Brain Injury in Mice

(2018) Rebecca J. Henry et al.   Neurotherapeutics

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

MicroRNA 155 and viral-induced neuroinflammation

(2017) Laura L. Dickey et al.   JOURNAL OF NEUROIMMUNOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Estrogen induces multiple regulatory B cell subtypes and promotes M2 microglia and neuroprotection during experimental autoimmune encephalomyelitis

(2016) Gil Benedek et al.   JOURNAL OF NEUROIMMUNOLOGY

Single and Compound Knock-outs of MicroRNA (miRNA)-155 and Its Angiogenic Gene TargetCCN1in Mice Alter Vascular and Neovascular Growth in the Retina via Resident Microglia

(2015) Lulu Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic inflammation and microglial activation: systematic review of animal experiments

(2015) Inge C.M. Hoogland et al.   Journal of Neuroinflammation

Diversity and plasticity of microglial cells in psychiatric and neurological disorders

(2015) Yutaka Nakagawa et al.   PHARMACOLOGY & THERAPEUTICS

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Integrated Expression Profiles of mRNA and miRNA in Polarized Primary Murine Microglia

(2013) Robert W. Freilich et al.   PLoS One

Assessing Activation States in Microglia

(2012) Carol A. Colton et al.   CNS & Neurological Disorders-Drug Targets

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production

(2011) Ana L. Cardoso et al.   IMMUNOLOGY

Astragalus polysaccharides regulate T cell-mediated immunity via CD11chighCD45RBlow DCs in vitro

(2010) Qing-yang Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration

(2010) Joanna Mikita et al.   Multiple Sclerosis Journal

CCL2 and Interleukin-6 Promote Survival of Human CD11b+Peripheral Blood Mononuclear Cells and Induce M2-type Macrophage Polarization

(2009) Hernan Roca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY