Target Sestrin2 to Rescue the Damaged Organ: Mechanistic Insight into Its Function
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Target Sestrin2 to Rescue the Damaged Organ: Mechanistic Insight into Its Function
Authors
Keywords
-
Journal
Oxidative Medicine and Cellular Longevity
Volume 2021, Issue -, Pages 1-19
Publisher
Hindawi Limited
Online
2021-11-03
DOI
10.1155/2021/8790369
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis
- (2021) Narjes Nasiri-Ansari et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sestrin2 is an endogenous antioxidant that improves contractile function in the heart during exposure to ischemia and reperfusion stress
- (2021) Yunxia Liu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Indoleamine 2,3-Dioxygenase 1 (IDO1) Promotes Cardiac Hypertrophy via a PI3K-AKT-mTOR-Dependent Mechanism
- (2021) Yang Liu et al. Cardiovascular Toxicology
- SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity
- (2020) Da Hyun Lee et al. Autophagy
- Pentamethylquercetin Attenuates Cardiac Remodeling via Activation of the Sestrins/Keap1/Nrf2 Pathway in MSG-Induced Obese Mice
- (2020) Jingxia Du et al. Biomed Research International
- Sirtuin 1: Endocan and Sestrin 2 in Different Biological Samples in Patients with Asthma. Does Severity Make the Difference?
- (2020) Zoe Tsilogianni et al. Journal of Clinical Medicine
- Liraglutide ameliorates obesity-related nonalcoholic fatty liver disease by regulating Sestrin2-mediated Nrf2/HO-1 pathway
- (2020) Xue Han et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Phytic acid exerts protective effects in cerebral ischemia-reperfusion injury by activating the anti-oxidative protein sestrin2
- (2020) Jing Liu et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Plasma sestrin2 concentrations and carotid atherosclerosis
- (2020) Yoshimi Kishimoto et al. CLINICA CHIMICA ACTA
- Empagliflozin Ameliorates Obesity-Related Cardiac Dysfunction by Regulating Sestrin2-Mediated AMPK-mTOR Signaling and Redox Homeostasis in High-Fat Diet–Induced Obese Mice
- (2020) Xiaodong Sun et al. DIABETES
- Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway
- (2020) Xinqi Zhuang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Sestrin 2 attenuates sepsis‐associated encephalopathy through the promotion of autophagy in hippocampal neurons
- (2020) Lili Luo et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Melatonin inhibits vascular smooth muscle cell proliferation and apoptosis through upregulation of Sestrin2
- (2020) Seunghyeong Lee et al. Experimental and Therapeutic Medicine
- Salivary Oxidative Stress Increases with the Progression of Chronic Heart Failure
- (2020) Anna Klimiuk et al. Journal of Clinical Medicine
- Elevating sestrin2 attenuates endoplasmic reticulum stress and improves functional recovery through autophagy activation after spinal cord injury
- (2020) Yao Li et al. CELL BIOLOGY AND TOXICOLOGY
- Sestrin2 overexpression alleviates hydrogen peroxide-induced apoptosis and oxidative stress in retinal ganglion cells by enhancing Nrf2 activation via Keap1 downregulation
- (2020) Yazhi Fan et al. CHEMICO-BIOLOGICAL INTERACTIONS
- PD-1/PD-L1 in cardiovascular disease
- (2020) YunFeng Sun et al. CLINICA CHIMICA ACTA
- Association between Plasma Sestrin2 Levels and the Presence and Severity of Coronary Artery Disease
- (2020) Yoshimi Kishimoto et al. DISEASE MARKERS
- Diagnostic Value of Sestrin2 in Patients with Obstructive Sleep Apnea
- (2020) Jiagui Chai et al. Metabolic Syndrome and Related Disorders
- Luteolin prevents liver from tunicamycin-induced endoplasmic reticulum stress via nuclear factor erythroid 2-related factor 2-dependent sestrin 2 induction
- (2020) Kyung Hwan Jegal et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Sestrin2 modulates cardiac inflammatory response through maintaining redox homeostasis during ischemia and reperfusion
- (2020) Di Ren et al. Redox Biology
- Oxidative stress-based therapeutics in COPD
- (2020) Peter J. Barnes Redox Biology
- Obstructive Sleep Apnea and Circulating Biomarkers of Oxidative Stress: A Cross-Sectional Study
- (2020) Bernardo U. Peres et al. Antioxidants
- Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats
- (2020) Yixin Li et al. BRAIN RESEARCH
- Nrf2 inhibition induces oxidative stress, renal inflammation and hypertension in mice
- (2020) Zeba Farooqui et al. CLINICAL AND EXPERIMENTAL HYPERTENSION
- Substrate metabolism regulated by Sestrin2–mTORC1 alleviates pressure overload-induced cardiac hypertrophy in aged heart
- (2020) Nanhu Quan et al. Redox Biology
- Sestrin2 Expression Has Regulatory Properties and Prognostic Value in Lung Cancer
- (2020) Hee Sung Chae et al. Journal of Personalized Medicine
- Mitochondrial quality surveillance as a therapeutic target in myocardial infarction
- (2020) Hang Zhu et al. Acta Physiologica
- Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway
- (2020) Shiao Ding et al. Aging-US
- Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling
- (2020) Xiaobin Liu et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Correlation between sestrin2 expression and airway remodeling in COPD
- (2020) Da-Wei Zhang et al. BMC Pulmonary Medicine
- Sestrin2 maintains OXPHOS integrity to modulate cardiac substrate metabolism during ischemia and reperfusion
- (2020) Di Ren et al. Redox Biology
- Calcium/calmodulin-dependent protein kinase II causes atrial structural remodeling associated with atrial fibrillation and heart failure
- (2019) Zhao Liu et al. HEART RHYTHM
- Investigation of Urinary Sestrin2 in Patients with Obstructive Sleep Apnea
- (2019) Lu Bai et al. LUNG
- Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association
- (2019) Emelia J. Benjamin et al. CIRCULATION
- Pentamethylquercetin protects against cardiac remodeling via activation of Sestrin2
- (2019) Jing-Xia Du et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibitory Effect of Sestrin2 on Hepatic Stellate Cell Activation and Liver Fibrosis via Blocking Transforming Growth Factor-β Signaling
- (2019) Ji Hye Yang et al. ANTIOXIDANTS & REDOX SIGNALING
- Cardioprotective roles of Sestrin1 and Sestrin2 against doxorubicin cardiotoxicity
- (2019) Ruiting Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mitophagy and mitochondrial integrity in cardiac ischemia-reperfusion injury
- (2019) Mingjie Yang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Roles of eNOS in atherosclerosis treatment
- (2019) Fen-fang Hong et al. INFLAMMATION RESEARCH
- ERK: A Key Player in the Pathophysiology of Cardiac Hypertrophy
- (2019) Simona Gallo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
- (2019) Anju Singh et al. MOLECULES
- Letter by Li et al Regarding Article, “Dectin-1 Contributes to Myocardial Ischemia/Reperfusion Injury by Regulating Macrophage Polarization and Neutrophil Infiltration”
- (2019) Yangxin Li et al. CIRCULATION
- p53 mediates PEDF‑induced autophagy in human umbilical vein endothelial cells through sestrin2 signaling
- (2019) Tiangui Chen et al. Molecular Medicine Reports
- Sestrin2 overexpression attenuates focal cerebral ischemic injury in rat by increasing Nrf2/HO-1 pathway-mediated angiogenesis
- (2019) Peng Wang et al. NEUROSCIENCE
- Dysregulated autophagy in COPD: A pathogenic process to be deciphered
- (2019) W.S. Daniel Tan et al. PHARMACOLOGICAL RESEARCH
- Increased plasma sestrin2 concentrations in patients with chronic heart failure and predicted the occurrence of major adverse cardiac events: A 36-month follow-up cohort study
- (2019) Haixiong Wang et al. CLINICA CHIMICA ACTA
- Antioxidant and antihypertensive responses to oral nitrite involves activation of the Nrf2 pathway
- (2019) Jefferson H. Amaral et al. FREE RADICAL BIOLOGY AND MEDICINE
- SESN2 protects against doxorubicin-induced cardiomyopathy via rescuing mitophagy and improving mitochondrial function
- (2019) Panxia Wang et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Sestrin2 is involved in asthma: a case–control study
- (2019) Yanfang Kang et al. Allergy Asthma and Clinical Immunology
- Explorating the Involvement of Plasma Sestrin2 in Obstructive Sleep Apnea
- (2019) Rong Jiang et al. Canadian Respiratory Journal
- Calmodulin kinase II regulates atrial myocyte late sodium current, calcium handling, and atrial arrhythmia
- (2019) Amara Greer-Short et al. HEART RHYTHM
- Sestrin2 as Serum Protein Marker and Potential Therapeutic Target for Parkinson’s Disease
- (2019) Nitish Rai et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Sestrin2: Its Potential Role and Regulatory Mechanism in Host Immune Response in Diseases
- (2019) Li-Xue Wang et al. Frontiers in Immunology
- Mitochondrial ROS Drive Sudden Cardiac Death and Chronic Proteome Remodeling in Heart FailureNovelty and Significance
- (2018) Swati Dey et al. CIRCULATION RESEARCH
- Sestrin2 facilitates glutamine-dependent transcription of PGC-1α and survival of liver cancer cells under glucose limitation
- (2018) Ashish Kumar et al. FEBS Journal
- Renin–angiotensin–aldosterone blockade reduces atrial fibrillation in hypertrophic cardiomyopathy
- (2018) Chen-Yu Huang et al. HEART
- Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Na v 1.5 gain-of-function mutation (G213D)
- (2018) Kirstine Calloe et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Nrf2 attenuates inflammatory response in COPD/emphysema: Crosstalk with Wnt3a/β-catenin and AMPK pathways
- (2018) Wenhui Cui et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway
- (2018) Nanhu Quan et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Knockdown of Sestrin2 Increases Lipopolysaccharide-Induced Oxidative Stress, Apoptosis, and Fibrotic Reactions in H9c2 Cells and Heart Tissues of Mice via an AMPK-Dependent Mechanism
- (2018) Hwan-Jin Hwang et al. MEDIATORS OF INFLAMMATION
- Reactive oxygen species mediated oxidative stress links diabetes and atrial fibrillation
- (2018) Xue Liang et al. Molecular Medicine Reports
- Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets
- (2018) Vikas Mishra et al. PHARMACOLOGY & THERAPEUTICS
- The impact of microRNA-122 and its target gene Sestrin-2 on the protective effect of ghrelin in angiotensin II-induced cardiomyocyte apoptosis
- (2018) Xiaotong Wang et al. RSC Advances
- SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation
- (2018) Ashish Kumar et al. Scientific Reports
- Targeting AMPK Signaling as a Neuroprotective Strategy in Parkinson’s Disease
- (2018) Daniel W. Curry et al. Journal of Parkinsons Disease
- Xanthine Oxidase Inhibitor Allopurinol Prevents Oxidative Stress‐Mediated Atrial Remodeling in Alloxan‐Induced Diabetes Mellitus Rabbits
- (2018) Yajuan Yang et al. Journal of the American Heart Association
- Involvement of epithelial-mesenchymal transition in liver fibrosis
- (2018) Ning Li et al. Saudi Journal of Gastroenterology
- Exploration of Novel Anti-Oxidant Protein Sestrin in Frailty Syndrome in Elderly
- (2018) Nitish Rai et al. Aging and Disease
- Mechanisms and Treatments of Oxidative Stress in Atrial Fibrillation
- (2018) Xiaomeng Ren et al. CURRENT PHARMACEUTICAL DESIGN
- Association of serum Sestrin2 level with metabolic risk factors in newly diagnosed drug-naïve type 2 diabetes
- (2018) Hye Soo Chung et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- MiR-4756 promotes albumin-induced renal tubular epithelial cell epithelial-to-mesenchymal transition and endoplasmic reticulum stress via targeting Sestrin2
- (2018) Yijie Jia et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Distinct patterns of atrial electrical and structural remodeling in angiotensin II mediated atrial fibrillation
- (2018) Hailey J. Jansen et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Sestrin2 regulates monocyte activation through AMPK-mTOR nexus under high-glucose and dyslipidemic conditions
- (2018) Saravanakumar Sundararajan et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials
- (2018) Thomas A Zelniker et al. LANCET
- Sestrin2 increases in aortas and plasma from aortic dissection patients and alleviates angiotensin II-induced smooth muscle cell apoptosis via the Nrf2 pathway
- (2018) Ting Xiao et al. LIFE SCIENCES
- Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke
- (2018) Changjun Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Rosemary Extracts Upregulate Nrf2, Sestrin2, and MRP2 Protein Level in Human Hepatoma HepG2 Cells
- (2017) Xiao-pei Tong et al. Evidence-based Complementary and Alternative Medicine
- Sestrin 2 induces autophagy and attenuates insulin resistance by regulating AMPK signaling in C2C12 myotubes
- (2017) Huige Li et al. EXPERIMENTAL CELL RESEARCH
- Sestrin2 prevents age-related intolerance to ischemia and reperfusion injury by modulating substrate metabolism
- (2017) Nanhu Quan et al. FASEB JOURNAL
- Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway
- (2017) Hyo Jeong Kim et al. FREE RADICAL BIOLOGY AND MEDICINE
- Association between oxidative stress and atrial fibrillation
- (2017) Ayman Samman Tahhan et al. HEART RHYTHM
- Selective Nrf2 Gene Deletion in the Rostral Ventrolateral Medulla Evokes Hypertension and Sympathoexcitation in MiceNovelty and Significance
- (2017) Lie Gao et al. HYPERTENSION
- PEDF improves atherosclerotic plaque stability by inhibiting macrophage inflammation response
- (2017) Hao Wen et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Sestrin 2 attenuates neonatal rat cardiomyocyte hypertrophy induced by phenylephrine via inhibiting ERK1/2
- (2017) Bin Dong et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- New and revisited approaches to preserving the reperfused myocardium
- (2017) Robert A. Kloner et al. Nature Reviews Cardiology
- Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea
- (2017) Celia Zhang et al. NEUROSCIENCE
- Loss of Nrf2 promotes rapid progression to heart failure following myocardial infarction
- (2017) Joshua Strom et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Schisandrin B attenuates CCl4-induced liver fibrosis in rats by regulation of Nrf2-ARE and TGF-β/Smad signaling pathways
- (2017) Qingshan Chen et al. Drug Design Development and Therapy
- Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
- (2017) Kelly L. Walton et al. Frontiers in Pharmacology
- Oxidative Stress-Mediated Atherosclerosis: Mechanisms and Therapies
- (2017) Xinyu Yang et al. Frontiers in Physiology
- Sestrin2 Suppresses Classically Activated Macrophages-Mediated Inflammatory Response in Myocardial Infarction through Inhibition of mTORC1 Signaling
- (2017) Keping Yang et al. Frontiers in Immunology
- Upregulation of sestrins protect atriums against oxidative damage and fibrosis in human and experimental atrial fibrillation
- (2017) Zengxiang Dong et al. Scientific Reports
- Hypertension and aging
- (2016) Thomas W. Buford AGEING RESEARCH REVIEWS
- Eupatilin induces Sestrin2-dependent autophagy to prevent oxidative stress
- (2016) Kyung Hwan Jegal et al. APOPTOSIS
- SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages
- (2016) Min-Ji Kim et al. Autophagy
- Vascular Smooth Muscle Cells in Atherosclerosis
- (2016) Martin R. Bennett et al. CIRCULATION RESEARCH
- Sestrin-2 is significantly increased in malignant pleural effusions due to lung cancer and is potentially secreted by pleural mesothelial cells
- (2016) Irene Tsilioni et al. CLINICAL BIOCHEMISTRY
- Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy
- (2016) Junlian Gu et al. DIABETES
- Mitochondrial pathways to cardiac recovery: TFAM
- (2016) George H. Kunkel et al. HEART FAILURE REVIEWS
- Relative Alterations in Blood-Based Levels of Sestrin in Alzheimer’s Disease and Mild Cognitive Impairment Patients
- (2016) Nitish Rai et al. JOURNAL OF ALZHEIMERS DISEASE
- Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups
- (2016) Xudan Shi et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- p53 coordinates decidual sestrin 2/AMPK/mTORC1 signaling to govern parturition timing
- (2016) Wenbo Deng et al. JOURNAL OF CLINICAL INVESTIGATION
- AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia
- (2016) Vlad G. Zaha et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Autophagy in acute kidney injury
- (2016) Gur P. Kaushal et al. KIDNEY INTERNATIONAL
- Sestrin2 induced by hypoxia inducible factor1 alpha protects the blood-brain barrier via inhibiting VEGF after severe hypoxic-ischemic injury in neonatal rats
- (2016) Xudan Shi et al. NEUROBIOLOGY OF DISEASE
- Senescent intimal foam cells are deleterious at all stages of atherosclerosis
- (2016) B. G. Childs et al. SCIENCE
- Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway
- (2016) Yan-Ling Wu et al. TOXICOLOGY LETTERS
- Sestrin2 Silencing Exacerbates Cerebral Ischemia/Reperfusion Injury by Decreasing Mitochondrial Biogenesis through the AMPK/PGC-1α Pathway in Rats
- (2016) Lingyu Li et al. Scientific Reports
- Resveratrol restored Nrf2 function, reduced renal inflammation, and mitigated hypertension in spontaneously hypertensive rats
- (2015) Apurva A. Javkhedkar et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Upregulation of Sestrin2 Expression Protects Against Macrophage Apoptosis Induced by Oxidized Low-Density Lipoprotein
- (2015) Hong-Juan Hu et al. DNA AND CELL BIOLOGY
- Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart
- (2015) Alex Morrison et al. FASEB JOURNAL
- Role of Nrf2 in the pathogenesis of atherosclerosis
- (2015) Junsei Mimura et al. FREE RADICAL BIOLOGY AND MEDICINE
- Role of sestrin2 in the regulation of proinflammatory signaling in macrophages
- (2015) Ji Hye Yang et al. FREE RADICAL BIOLOGY AND MEDICINE
- ER Stress and Autophagy Dysfunction Contribute to Fatty Liver in Diabetic Mice
- (2015) Quan Zhang et al. International Journal of Biological Sciences
- Sestrin 2 Protein Regulates Platelet-derived Growth Factor Receptor β (Pdgfrβ) Expression by Modulating Proteasomal and Nrf2 Transcription Factor Functions
- (2015) Ana Tomasovic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cardiac fibroblasts: from development to heart failure
- (2015) Thomas Moore-Morris et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Evolving Therapies for Myocardial Ischemia/Reperfusion Injury
- (2015) Borja Ibáñez et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Elevation of Sestrin-2 expression attenuates Sevoflurane induced neurotoxicity
- (2015) Wenbo Yi et al. METABOLIC BRAIN DISEASE
- Gossypol Acetic Acid Prevents Oxidative Stress-Induced Retinal Pigment Epithelial Necrosis by Regulating the FoxO3/Sestrin2 Pathway
- (2015) Jakub Hanus et al. MOLECULAR AND CELLULAR BIOLOGY
- Nuclear Factor-kappaB-Dependent Sestrin2 Induction Mediates the Antioxidant Effects of BDNF Against Mitochondrial Inhibition in Rat Cortical Neurons
- (2015) Chia-Lin Wu et al. MOLECULAR NEUROBIOLOGY
- Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
- (2015) R. A. Saxton et al. SCIENCE
- Sestrin2 inhibits mTORC1 through modulation of GATOR complexes
- (2015) Jeong Sig Kim et al. Scientific Reports
- MicroRNAs in vascular aging and atherosclerosis
- (2014) Rossella Menghini et al. AGEING RESEARCH REVIEWS
- AMPK inhibits cardiac hypertrophy by promoting autophagy via mTORC1
- (2014) Yanh Li et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- NHE1 deficiency in liver: Implications for non-alcoholic fatty liver disease
- (2014) Vikram Prasad et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Upregulation of sestrin-2 expression protects against endothelial toxicity of angiotensin II
- (2014) Lao Yi et al. CELL BIOLOGY AND TOXICOLOGY
- Disruption of Mammalian Target of Rapamycin Complex 1 in Macrophages Decreases Chemokine Gene Expression and Atherosclerosis
- (2014) Ding Ai et al. CIRCULATION RESEARCH
- Endothelial Dysfunction and Hypertension
- (2014) Ralf P. Brandes HYPERTENSION
- Sestrin2 Decreases Renal Oxidative Stress, Lowers Blood Pressure, and Mediates Dopamine D 2 Receptor–Induced Inhibition of Reactive Oxygen Species Production
- (2014) Yu Yang et al. HYPERTENSION
- Resveratrol prevents AngII-induced hypertension via AMPK activation and RhoA/ROCK suppression in mice
- (2014) Xia Cao et al. HYPERTENSION RESEARCH
- Quercetin regulates the sestrin 2-AMPK-p38 MAPK signaling pathway and induces apoptosis by increasing the generation of intracellular ROS in a p53-independent manner
- (2014) GUEN TAE KIM et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- The Role of Nrf2-Mediated Pathway in Cardiac Remodeling and Heart Failure
- (2014) Shanshan Zhou et al. Oxidative Medicine and Cellular Longevity
- Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species
- (2014) S.-H. Ro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD
- (2014) Á González-Rodríguez et al. Cell Death & Disease
- Hepatoprotective role of Sestrin2 against chronic ER stress
- (2014) Hwan-Woo Park et al. Nature Communications
- Antioxidant Activity of Sestrin 2 Controls Neuropathic Pain After Peripheral Nerve Injury
- (2013) Wiebke Kallenborn-Gerhardt et al. ANTIOXIDANTS & REDOX SIGNALING
- Toxico-pharmacological perspective of the Nrf2-Keap1 defense system against oxidative stress in kidney diseases
- (2013) Hideyuki Saito BIOCHEMICAL PHARMACOLOGY
- Sestrin-2, a repressor of PDGFR signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD
- (2013) J. Heidler et al. Disease Models & Mechanisms
- Induction of sestrin2 as an endogenous protective mechanism against amyloid beta-peptide neurotoxicity in primary cortical culture
- (2013) Yueh-Sheng Chen et al. EXPERIMENTAL NEUROLOGY
- mTOR and vascular remodeling in lung diseases: current challenges and therapeutic prospects
- (2013) Elena A. Goncharova FASEB JOURNAL
- Involvement of free radicals and oxidative stress in NAFLD/NASH
- (2013) Y. Sumida et al. FREE RADICAL RESEARCH
- Myocardial ischemia-reperfusion injury: a neglected therapeutic target
- (2013) Derek J. Hausenloy et al. JOURNAL OF CLINICAL INVESTIGATION
- Upregulation of Sestrin-2 Expression via P53 Protects Against 1-Methyl-4-Phenylpyridinium (MPP+) Neurotoxicity
- (2013) Zhou Daixing et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Sestrin 2 and AMPK Connect Hyperglycemia to Nox4-Dependent Endothelial Nitric Oxide Synthase Uncoupling and Matrix Protein Expression
- (2013) Assaad A. Eid et al. MOLECULAR AND CELLULAR BIOLOGY
- Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction
- (2013) So Hee Jin et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced death
- (2012) I Ben-Sahra et al. CELL DEATH AND DIFFERENTIATION
- Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis
- (2012) Xianghai Liao et al. Cell Metabolism
- Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage
- (2012) Soo Han Bae et al. Cell Metabolism
- Aging and Atherosclerosis
- (2012) Julie C. Wang et al. CIRCULATION RESEARCH
- Connecting mTORC1 signaling to SREBP-1 activation
- (2012) Inan Bakan et al. CURRENT OPINION IN LIPIDOLOGY
- Nrf2-ARE pathway regulates induction of Sestrin-2 expression
- (2012) Bo Yeon Shin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Antioxidant Sestrin-2 Redistribution to Neuronal Soma in Human Immunodeficiency Virus-Associated Neurocognitive Disorders
- (2012) Virawudh Soontornniyomkij et al. Journal of Neuroimmune Pharmacology
- A Meta-Analysis Reporting Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Patients Without Heart Failure
- (2012) Gianluigi Savarese et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Improved Glycaemia Correlates with Liver Fat Reduction in Obese, Type 2 Diabetes, Patients Given Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists
- (2012) Daniel J. Cuthbertson et al. PLoS One
- Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia
- (2012) Xiaoming Hu et al. STROKE
- Activation of hypoxia-inducible factor-1 protects airway epithelium against oxidant-induced barrier dysfunction
- (2011) Nels Olson et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Targeting inflammation by modulating the Jun/AP-1 pathway
- (2011) H. B. Schonthaler et al. ANNALS OF THE RHEUMATIC DISEASES
- Nrf2 Inhibits LXRα-Dependent Hepatic Lipogenesis by Competing with FXR for Acetylase Binding
- (2011) Hee Yeon Kay et al. ANTIOXIDANTS & REDOX SIGNALING
- Discovery of the Negative Regulator of Nrf2, Keap1: A Historical Overview
- (2010) Ken Itoh et al. ANTIOXIDANTS & REDOX SIGNALING
- Oxidative Stress and Hypertension: Current Concepts
- (2010) Ana M. Briones et al. CURRENT HYPERTENSION REPORTS
- Insulin Resistance in Nonalcoholic Fatty Liver Disease
- (2010) E. Bugianesi et al. CURRENT PHARMACEUTICAL DESIGN
- Inactivation of sestrin 2 induces TGF- signaling and partially rescues pulmonary emphysema in a mouse model of COPD
- (2010) F. Wempe et al. Disease Models & Mechanisms
- Role of autophagy in heart failure associated with aging
- (2010) Guido R. Y. De Meyer et al. HEART FAILURE REVIEWS
- VEGF Promotes Angiogenesis and Functional Recovery in Stroke Rats
- (2010) Ji-Ping Yang et al. JOURNAL OF INVESTIGATIVE SURGERY
- Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis
- (2009) Sudhir Chowdhry et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cardiovascular Complications of Obstructive Sleep Apnea Syndrome: Evidence from Children
- (2009) Rakesh Bhattacharjee et al. PROGRESS IN CARDIOVASCULAR DISEASES
- Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)
- (2008) Masato Yoneda et al. BMC GASTROENTEROLOGY
- Oxidative stress and left ventricular remodelling after myocardial infarction
- (2008) M. Hori et al. CARDIOVASCULAR RESEARCH
- p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
- (2008) Andrei V. Budanov et al. CELL
- Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury
- (2008) Elizabeth Murphy et al. PHYSIOLOGICAL REVIEWS
- Disruption of Nrf2, a Key Inducer of Antioxidant Defenses, Attenuates ApoE-Mediated Atherosclerosis in Mice
- (2008) Thomas E. Sussan et al. PLoS One
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now