Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

Bcl-2 family members: Dual regulators of apoptosis and autophagy

(2014) Beth Levine et al.   Autophagy

Blocking autophagy enhances the apoptosis effect of bufalin on human hepatocellular carcinoma cells through endoplasmic reticulum stress and JNK activation

(2013) Fengli Hu et al.   APOPTOSIS

Non-alcoholic fatty liver disease: a massive problem

(2013) C. P. Day   CLINICAL MEDICINE

Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice

(2013) Chih-Wen Lin et al.   JOURNAL OF HEPATOLOGY

The Adaptive Endoplasmic Reticulum Stress Response to Lipotoxicity in Progressive Human Nonalcoholic Fatty Liver Disease

(2013) April D. Lake et al.   TOXICOLOGICAL SCIENCES

Selection of autophagy or apoptosis in cells exposed to ER-stress depends on ATF4 expression pattern with or without CHOP expression

(2013) H. Matsumoto et al.   Biology Open

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Induction of Autophagy by Palmitic Acid via Protein Kinase C-mediated Signaling Pathway Independent of mTOR (Mammalian Target of Rapamycin)

(2012) Shi Hao Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thapsigargin distinguishes membrane fusion in the late stages of endocytosis and autophagy

(2011) Ian G. Ganley et al.   Autophagy

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

(2011) H Kato et al.   CELL DEATH AND DIFFERENTIATION

Changes in the Prevalence of the Most Common Causes of Chronic Liver Diseases in the United States From 1988 to 2008

(2011) Zobair M. Younossi et al.   Clinical Gastroenterology and Hepatology

Functions of Autophagy in Hepatic and Pancreatic Physiology and Disease

(2011) Mark J. Czaja   GASTROENTEROLOGY

Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis

(2011) Mary E. Rinella et al.   HEPATOLOGY

Activation of autophagy protects against acetaminophen-induced hepatotoxicity

(2011) Hong-Min Ni et al.   HEPATOLOGY

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

(2011) Satoshi Shimizu et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by autophagy: pathophysiological implications

(2010) Mark J. Czaja   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Recent advances in nonalcoholic fatty liver disease

(2010) Onpan Cheung et al.   CURRENT OPINION IN GASTROENTEROLOGY

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

Stress Signaling in the Methionine-Choline–Deficient Model of Murine Fatty Liver Disease

(2010) Russell K. Soon et al.   GASTROENTEROLOGY

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

(2010) Wen–Xing Ding et al.   GASTROENTEROLOGY

Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

(2010) Brent A. Neuschwander-Tetri   HEPATOLOGY

PKCδ Is Activated in a Dietary Model of Steatohepatitis and Regulates Endoplasmic Reticulum Stress and Cell Death

(2010) Michael W. Greene et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C

(2010) Carmelo García-Monzón et al.   JOURNAL OF HEPATOLOGY

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

TOR-dependent control of autophagy: biting the hand that feeds

(2009) Thomas P Neufeld   CURRENT OPINION IN CELL BIOLOGY

Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia

(2009) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JNK1-dependent PUMA Expression Contributes to Hepatocyte Lipoapoptosis

(2009) Sophie C. Cazanave et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mantle skewness and ridge segmentation

(2009) Satish C. Singh et al.   NATURE

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease

(2008) Harmeet Malhi et al.   SEMINARS IN LIVER DISEASE

Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

(2007) Puneet Puri et al.   GASTROENTEROLOGY