The inflammatory response triggered by Influenza virus: a two edged sword

Control of influenza infection is impaired by diminished interferon-γ secretion by CD4 T cells in the lungs of toddler mice

(2016) David Verhoeven et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Influenza A virus-induced release of interleukin-10 inhibits the anti-microbial activities of invariant natural killer T cells during invasive pneumococcal superinfection

(2016) A Barthelemy et al.   Mucosal Immunology

RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection

(2016) Matheswaran Kandasamy et al.   PLoS Pathogens

A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection

(2016) Jonathan Maelfait et al.   PLoS Pathogens

Functional Interplay between Type I and II Interferons Is Essential to Limit Influenza A Virus-Induced Tissue Inflammation

(2016) Sebastian A. Stifter et al.   PLoS Pathogens

Balancing Immune Protection and Immune Pathology by CD8+ T-Cell Responses to Influenza Infection

(2016) Susu Duan et al.   Frontiers in Immunology

What Lies Beneath: Antibody Dependent Natural Killer Cell Activation by Antibodies to Internal Influenza Virus Proteins

(2016) Hillary A. Vanderven et al.   EBioMedicine

The Role of Viral, Host, and Secondary Bacterial Factors in Influenza Pathogenesis

(2015) John C. Kash et al.   AMERICAN JOURNAL OF PATHOLOGY

Inflammatory impact of IFN-γ in CD8+ T cell-mediated lung injury is mediated by both Stat1-dependent and -independent pathways

(2015) Chilakamarti V. Ramana et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Influenza infection induces host DNA damage and dynamic DNA damage responses during tissue regeneration

(2015) Na Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection

(2015) G. T. Ellis et al.   EMBO REPORTS

Pandemic influenza virus, pH1N1, induces asthmatic symptoms via activation of innate lymphoid cells

(2015) D. H. Shim et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Infectious Progeny of 2009 A (H1N1) Influenza Virus Replicated in and Released from Human Neutrophils

(2015) Zhang Zhang et al.   Scientific Reports

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease

(2014) Mark D. Turner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Influenza Promotes Pneumococcal Growth during Coinfection by Providing Host Sialylated Substrates as a Nutrient Source

(2014) Steven J. Siegel et al.   Cell Host & Microbe

Treatment With Anti-C5a Antibody Improves the Outcome of H7N9 Virus Infection in African Green Monkeys

(2014) Shihui Sun et al.   CLINICAL INFECTIOUS DISEASES

C5a/C5aR pathway is essential for the pathogenesis of murine viral fulminant hepatitis by way of potentiating Fgl2/fibroleukin expression

(2014) Gui-lian Xu et al.   HEPATOLOGY

N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury

(2014) Rui-Hua Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Leukotriene B 4 Induces Release of Antimicrobial Peptides in Lungs of Virally Infected Mice

(2014) Éric Gaudreault et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: T-bet and IL-27R Are Critical for In Vivo IFN-  Production by CD8 T Cells during Infection

(2014) K. D. Mayer et al.   JOURNAL OF IMMUNOLOGY

CCR2+ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality

(2014) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Activation of A1-Adenosine Receptors Promotes Leukocyte Recruitment to the Lung and Attenuates Acute Lung Injury in Mice Infected with Influenza A/WSN/33 (H1N1) Virus

(2014) F. Aeffner et al.   JOURNAL OF VIROLOGY

The co-pathogenesis of influenza viruses with bacteria in the lung

(2014) Jonathan A. McCullers   NATURE REVIEWS MICROBIOLOGY

Deletion of the Complement C5a Receptor Alleviates the Severity of Acute Pneumococcal Otitis Media following Influenza A Virus Infection in Mice

(2014) Hua Hua Tong et al.   PLoS One

PI3K/Akt Signaling Pathway Modulates Influenza Virus Induced Mouse Alveolar Macrophage Polarization to M1/M2b

(2014) Xiangfeng Zhao et al.   PLoS One

Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection

(2014) S. M. Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Magnitude of influenza virus replication and cell damage is associated with interleukin-6 production in primary cultures of human tracheal epithelium

(2014) Mutsuo Yamaya et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Pathogenic potential of interferon αβ in acute influenza infection

(2014) Sophia Davidson et al.   Nature Communications

Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza

(2014) Francesca Diane M. Liu et al.   PLoS Pathogens

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

(2014) Christoph Schneider et al.   PLoS Pathogens

Cytokine and Chemokine Profiles in Lung Tissues from Fatal Cases of 2009 Pandemic Influenza A (H1N1)

(2013) Rongbao Gao et al.   AMERICAN JOURNAL OF PATHOLOGY

IL-22 Is Essential for Lung Epithelial Repair following Influenza Infection

(2013) Derek A. Pociask et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of Complement Activation Alleviates Acute Lung Injury Induced by Highly Pathogenic Avian Influenza H5N1 Virus Infection

(2013) Shihui Sun et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Development of cellular signaling pathway inhibitors as new antivirals against influenza

(2013) Oliver Planz   ANTIVIRAL RESEARCH

PEGylated human catalase elicits potent therapeutic effects on H1N1 influenza-induced pneumonia in mice

(2013) Xunlong Shi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus

(2013) Yingxia Liu et al.   BMC IMMUNOLOGY

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

(2013) Masayuki Morita et al.   CELL

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

Switch from protective to adverse inflammation during influenza: viral determinants and hemostasis are caught as culprits

(2013) Fatma Berri et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected withStreptococcus pneumoniae

(2013) Thomas Kuri et al.   CELLULAR MICROBIOLOGY

CD8+Treg cells suppress CD8+T cell-responses by IL-10-dependent mechanism during H5N1 influenza virus infection

(2013) Qiang Zou et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NK cells exacerbate the pathology of influenza virus infection in mice

(2013) Gang Zhou et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The role of pro-resolution lipid mediators in infectious disease

(2013) Clark D. Russell et al.   IMMUNOLOGY

Entry of influenza A virus: host factors and antiviral targets

(2013) T. O. Edinger et al.   JOURNAL OF GENERAL VIROLOGY

Influenza A Exacerbates Staphylococcus aureus Pneumonia by Attenuating IL-1  Production in Mice

(2013) K. M. Robinson et al.   JOURNAL OF IMMUNOLOGY

Influenza A Virus Exacerbates Staphylococcus aureus Pneumonia in Mice by Attenuating Antimicrobial Peptide Production

(2013) Keven M. Robinson et al.   JOURNAL OF INFECTIOUS DISEASES

Interleukin-22 Reduces Lung Inflammation during Influenza A Virus Infection and Protects against Secondary Bacterial Infection

(2013) S. Ivanov et al.   JOURNAL OF VIROLOGY

IL-1βand IL-6 Upregulation in Children with H1N1 Influenza Virus Infection

(2013) Antonio Chiaretti et al.   MEDIATORS OF INFLAMMATION

Activation Mechanisms of Natural Killer Cells during Influenza Virus Infection

(2013) Ilwoong Hwang et al.   PLoS One

Complement C5 Activation during Influenza A Infection in Mice Contributes to Neutrophil Recruitment and Lung Injury

(2013) Cristiana C. Garcia et al.   PLoS One

ADAM17-Mediated Processing of TNF-α Expressed by Antiviral Effector CD8+ T Cells Is Required for Severe T-Cell-Mediated Lung Injury

(2013) Matthew P. DeBerge et al.   PLoS One

Role of Tissue Protection in Lethal Respiratory Viral-Bacterial Coinfection

(2013) A. M. Jamieson et al.   SCIENCE

Viral Pathogens and Acute Lung Injury: Investigations Inspired by the SARS Epidemic and the 2009 H1N1 Influenza Pandemic

(2013) Michael Matthay et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Transport of the Influenza Virus Genome from Nucleus to Nucleus

(2013) Edward Hutchinson et al.   Viruses-Basel

Differential lung NK cell responses in avian influenza virus infected chickens correlate with pathogenicity

(2013) Christine A. Jansen et al.   Scientific Reports

Clearance of influenza virus infections by T cells: risk of collateral damage?

(2013) MLB Hillaire et al.   Current Opinion in Virology

Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia

(2013) Katrin Högner et al.   PLoS Pathogens

Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

(2013) Julie L. McAuley et al.   PLoS Pathogens

Group 2 Innate Lymphoid Cell Production of IL-5 Is Regulated by NKT Cells during Influenza Virus Infection

(2013) Stacey Ann Gorski et al.   PLoS Pathogens

Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia

(2013) Stefania Crotta et al.   PLoS Pathogens

Reduction of influenza virus-induced lung inflammation and mortality in animals treated with a phosophodisestrase-4 inhibitor and a selective serotonin reuptake inhibitor

(2013) Geeta Sharma et al.   Emerging Microbes & Infections

Immunopathology in influenza virus infection: Uncoupling the friend from foe

(2012) Daniela Damjanovic et al.   CLINICAL IMMUNOLOGY

Do specific virus–bacteria pairings drive clinical outcomes of pneumonia?

(2012) J.A. McCullers   CLINICAL MICROBIOLOGY AND INFECTION

Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung

(2012) Laurel A Monticelli et al.   CURRENT OPINION IN IMMUNOLOGY

Doxycycline treatment attenuates acute lung injury in mice infected with virulent influenza H3N2 virus: Involvement of matrix metalloproteinases

(2012) H.H. Ng et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Effect of statin treatments on highly pathogenic avian influenza H5N1, seasonal and H1N1pdm09 virus infections in BALB/c mice

(2012) Yohichi Kumaki et al.   Future Virology

Influenza A Virus Induces Interleukin-27 through Cyclooxygenase-2 and Protein Kinase A Signaling

(2012) Li Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical Role of Natural Killer Cells in Lung Immunopathology During Influenza Infection in Mice

(2012) Mohamed F. Abdul-Careem et al.   JOURNAL OF INFECTIOUS DISEASES

Eicosanoids and Respiratory Viral Infection: Coordinators of Inflammation and Potential Therapeutic Targets

(2012) Mary K. McCarthy et al.   MEDIATORS OF INFLAMMATION

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Systemic Corticosteroids and Early Administration of Antiviral Agents for Pneumonia with Acute Wheezing due to Influenza A(H1N1)pdm09 in Japan

(2012) Koichiro Kudo et al.   PLoS One

CCR2 Defines a Distinct Population of NK Cells and Mediates Their Migration during Influenza Virus Infection in Mice

(2012) Mary J. G. van Helden et al.   PLoS One

Evasion of Influenza A Viruses from Innate and Adaptive Immune Responses

(2012) Carolien E. van de Sandt et al.   Viruses-Basel

Pathogenesis of influenza virus infections: the good, the bad and the ugly

(2012) T Kuiken et al.   Current Opinion in Virology

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

Corticosteroid Treatment in Critically Ill Patients with Pandemic Influenza A/H1N1 2009 Infection

(2011) Sung-Han Kim et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Successive influenza virus infection and Streptococcus pneumoniae stimulation alter human dendritic cell function

(2011) Yuet Wu et al.   BMC INFECTIOUS DISEASES

A New Shield for a Cytokine Storm

(2011) Akiko Iwasaki et al.   CELL

Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

(2011) John R. Teijaro et al.   CELL

A critical role of IL-17 in modulating the B-cell response during H5N1 influenza virus infection

(2011) Xiaohui Wang et al.   Cellular & Molecular Immunology

Early Use of Glucocorticoids Was a Risk Factor for Critical Disease and Death From pH1N1 Infection

(2011) K. Han et al.   CLINICAL INFECTIOUS DISEASES

Immunomodulatory therapy for severe influenza

(2011) Ilyse Darwish et al.   Expert Review of Anti-Infective Therapy

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Virulence determinants of pandemic influenza viruses

(2011) Donna M. Tscherne et al.   JOURNAL OF CLINICAL INVESTIGATION

Control of Pathogenic CD4 T Cells and Lethal Immunopathology by Signaling Immunoadaptor DAP12 during Influenza Infection

(2011) Sarah McCormick et al.   JOURNAL OF IMMUNOLOGY

Potential Role of Invariant NKT Cells in the Control of Pulmonary Inflammation and CD8+ T Cell Response during Acute Influenza A Virus H3N2 Pneumonia

(2011) C. Paget et al.   JOURNAL OF IMMUNOLOGY

Association Between Use of Statins and Mortality Among Patients Hospitalized With Laboratory-Confirmed Influenza Virus Infections: A Multistate Study

(2011) M. L. Vandermeer et al.   JOURNAL OF INFECTIOUS DISEASES

Lowering the Threshold of Lung Innate Immune Cell Activation Alters Susceptibility to Secondary Bacterial Superinfection

(2011) John Goulding et al.   JOURNAL OF INFECTIOUS DISEASES

Influenza A Virus Infection Results in a Robust, Antigen-Responsive, and Widely Disseminated Foxp3+ Regulatory T Cell Response

(2011) R. J. Betts et al.   JOURNAL OF VIROLOGY

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

(2011) Laurel A Monticelli et al.   NATURE IMMUNOLOGY

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

(2011) Ya-Jen Chang et al.   NATURE IMMUNOLOGY

A Protective Role for Complement C3 Protein during Pandemic 2009 H1N1 and H5N1 Influenza A Virus Infection

(2011) Kevin B. O'Brien et al.   PLoS One

Pre-Admission Statin Use and In-Hospital Severity of 2009 Pandemic Influenza A(H1N1) Disease

(2011) Stephen J. Brett et al.   PLoS One

Cytokine Response Patterns in Severe Pandemic 2009 H1N1 and Seasonal Influenza among Hospitalized Adults

(2011) Nelson Lee et al.   PLoS One

Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus

(2011) K. B. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LTB4 increases nasal neutrophil activity and conditions neutrophils to exert antiviral effects

(2011) Henrik Widegren et al.   RESPIRATORY MEDICINE

Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity

(2011) S. N. Lauder et al.   THORAX

Immune responses to influenza virus infection

(2011) J.H.C.M. Kreijtz et al.   VIRUS RESEARCH

Lethal Synergism of 2009 Pandemic H1N1 Influenza Virus and Streptococcus pneumoniae Coinfection Is Associated with Loss of Murine Lung Repair Responses

(2011) J. C. Kash et al.   mBio

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

(2011) Ross Vlahos et al.   PLoS Pathogens

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

Original Article: Peroxisome proliferator-activated receptor and AMP-activated protein kinase agonists protect against lethal influenza virus challenge in mice

(2010) Carson E. Moseley et al.   Influenza and Other Respiratory Viruses

CCR2-Antagonist Prophylaxis Reduces Pulmonary Immune Pathology and Markedly Improves Survival during Influenza Infection

(2010) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Influenza A Inhibits Th17-Mediated Host Defense against Bacterial Pneumonia in Mice

(2010) A. Kudva et al.   JOURNAL OF IMMUNOLOGY

Mice Lacking Both TNF and IL‐1 Receptors Exhibit Reduced Lung Inflammation and Delay in Onset of Death following Infection with a Highly Virulent H5N1 Virus

(2010) Lucy A. Perrone et al.   JOURNAL OF INFECTIOUS DISEASES

Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo

(2010) N. A. Jewell et al.   JOURNAL OF VIROLOGY

Critical Role of Airway Macrophages in Modulating Disease Severity during Influenza Virus Infection of Mice

(2010) M. D. Tate et al.   JOURNAL OF VIROLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes

(2010) Ana Clara Monsalvo et al.   NATURE MEDICINE

Role of Host Immune Response and Viral Load in the Differential Outcome of Pandemic H1N1 (2009) Influenza Virus Infection in Indian Patients

(2010) Vidya A. Arankalle et al.   PLoS One

Three fatal cases of pandemic 2009 influenza A virus infection in Shenzhen are associated with cytokine storm

(2010) Xiao-Wen Cheng et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

PPAR-γ Activation As an Anti-inflammatory Therapy for Respiratory Virus Infections

(2010) Josep Bassaganya-Riera et al.   VIRAL IMMUNOLOGY

IFN-γ production downstream of NKT cell activation in mice infected with influenza virus enhances the cytolytic activities of both NK cells and viral antigen-specific CD8+ T cells

(2010) Hiroki Ishikawa et al.   VIROLOGY

Platelet-Activating Factor Receptor Plays a Role in Lung Injury and Death Caused by Influenza A in Mice

(2010) Cristiana C. Garcia et al.   PLoS Pathogens

MCP-1 Antibody Treatment Enhances Damage and Impedes Repair of the Alveolar Epithelium in Influenza Pneumonitis

(2009) T. Narasaraju et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Influenza Virus Infection Decreases Tracheal Mucociliary Velocity and Clearance ofStreptococcus pneumoniae

(2009) Lynnelle A. Pittet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

N-acetyl-l-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus

(2009) Janina Geiler et al.   BIOCHEMICAL PHARMACOLOGY

Interferons and viral infections

(2009) Volker Fensterl et al.   BIOFACTORS

Evaluation of the efficacy and safety of a statin/caffeine combination against H5N1, H3N2 and H1N1 virus infection in BALB/c mice

(2009) Zeyu Liu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Fighting the Flu with Inflammasome Signaling

(2009) David M. Owen et al.   IMMUNITY

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

Confronting the next influenza pandemic with anti-inflammatory and immunomodulatory agents: why they are needed and how they might work

(2009) David S. Fedson   Influenza and Other Respiratory Viruses

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Critical Role of IL-17RA in Immunopathology of Influenza Infection

(2009) C. R. Crowe et al.   JOURNAL OF IMMUNOLOGY

IL-10 Deficiency Unleashes an Influenza-Specific Th17 Response and Enhances Survival against High-Dose Challenge

(2009) K. K. McKinstry et al.   JOURNAL OF IMMUNOLOGY

Tc17, a Unique Subset of CD8 T Cells That Can Protect against Lethal Influenza Challenge

(2009) H. Hamada et al.   JOURNAL OF IMMUNOLOGY

Early Control of H5N1 Influenza Virus Replication by the Type I Interferon Response in Mice

(2009) K. J. Szretter et al.   JOURNAL OF VIROLOGY

Influenza Morbidity and Mortality in Elderly Patients Receiving Statins: A Cohort Study

(2009) Jeffrey C. Kwong et al.   PLoS One

A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection

(2009) D. Marsolais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

(2009) C. R. Baskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune responses to influenza A H5N1: friend or foe?

(2009) Joseph Sriyal Malik Peiris et al.   TRENDS IN IMMUNOLOGY

Immunity to Respiratory Viruses

(2008) Jacob E. Kohlmeier et al.   Annual Review of Immunology

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Activation of invariant NKT cells enhances the innate immune response and improves the disease course in influenza A virus infection

(2008) Ling‐Pei Ho et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans

(2008) Carmela De Santo et al.   JOURNAL OF CLINICAL INVESTIGATION

Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

(2008) Arnaud Didierlaurent et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hyperinduction of Cyclooxygenase‐2–Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection

(2008) Suki M. Y. Lee et al.   JOURNAL OF INFECTIOUS DISEASES

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES

Treatment with Protein Synthesis Inhibitors Improves Outcomes of Secondary Bacterial Pneumonia after Influenza

(2008) Åsa Karlström et al.   JOURNAL OF INFECTIOUS DISEASES

Neutrophils Play an Essential Role in Cooperation with Antibody in both Protection against and Recovery from Pulmonary Infection with Influenza Virus in Mice

(2008) H. Fujisawa   JOURNAL OF VIROLOGY

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE

Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus

(2008) B.-J. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

(2008) Markus Mordstein et al.   PLoS Pathogens

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

(2008) Caroline Sommereyns et al.   PLoS Pathogens

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY