Switch from protective to adverse inflammation during influenza: viral determinants and hemostasis are caught as culprits

Plasmacytoid Dendritic Cells Migrate in Afferent Skin Lymph

(2014) Florentia Pascale et al.   JOURNAL OF IMMUNOLOGY

NK cells exacerbate the pathology of influenza virus infection in mice

(2013) Gang Zhou et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PAR-1 contributes to the innate immune response during viral infection

(2013) Silvio Antoniak et al.   JOURNAL OF CLINICAL INVESTIGATION

The TLR4 antagonist Eritoran protects mice from lethal influenza infection

(2013) Kari Ann Shirey et al.   NATURE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modulation of Protease Activated Receptor 1 Influences Human Metapneumovirus Disease Severity in a Mouse Model

(2013) Laetitia Aerts et al.   PLoS One

Role of Fibrinolysis in Sepsis

(2013) Satoshi Gando   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Functional Characterization of HLA-G+ Regulatory T Cells in HIV-1 Infection

(2013) Chun Li et al.   PLoS Pathogens

Type I IFN Triggers RIG-I/TLR3/NLRP3-dependent Inflammasome Activation in Influenza A Virus Infected Cells

(2013) Julien Pothlichet et al.   PLoS Pathogens

Plasminogen Controls Inflammation and Pathogenesis of Influenza Virus Infections via Fibrinolysis

(2013) Fatma Berri et al.   PLoS Pathogens

NK cell MHC class I specific receptors (KIR): from biology to clinical intervention

(2012) Ariane Thielens et al.   CURRENT OPINION IN IMMUNOLOGY

HLA-G1 and HLA-G5 active dimers are present in malignant cells and effusions: The influence of the tumor microenvironment

(2012) Sonia Zilberman et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PAR1 contributes to influenza A virus pathogenicity in mice

(2012) Khaled Khoufache et al.   JOURNAL OF CLINICAL INVESTIGATION

HLA-G 3′ Untranslated Region 14–Base Pair Deletion: Association With Poor Survival in an HIV-1–Infected Zimbabwean Population

(2012) Margit Hørup Larsen et al.   JOURNAL OF INFECTIOUS DISEASES

Critical Role of Natural Killer Cells in Lung Immunopathology During Influenza Infection in Mice

(2012) Mohamed F. Abdul-Careem et al.   JOURNAL OF INFECTIOUS DISEASES

Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury

(2012) Susanne Herold et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Intranasal Treatment with Poly(I{middle dot}C) Protects Aged Mice from Lethal Respiratory Virus Infections

(2012) J. Zhao et al.   JOURNAL OF VIROLOGY

The PA-Gene-Mediated Lethal Dissemination and Excessive Innate Immune Response Contribute to the High Virulence of H5N1 Avian Influenza Virus in Mice

(2012) J. Hu et al.   JOURNAL OF VIROLOGY

Influenza Virus A/Beijing/501/2009(H1N1) NS1 Interacts with β-Tubulin and Induces Disruption of the Microtubule Network and Apoptosis on A549 Cells

(2012) Xueqing Han et al.   PLoS One

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

Pathogenesis of influenza virus infections: the good, the bad and the ugly

(2012) T Kuiken et al.   Current Opinion in Virology

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

(2011) John R. Teijaro et al.   CELL

Plasma soluble human leukocyte antigen-G expression is a potential clinical biomarker in patients with hepatitis B virus infection

(2011) Wei-Wu Shi et al.   HUMAN IMMUNOLOGY

Role for proteases and HLA-G in the pathogenicity of influenza A viruses

(2011) Marie-Laure Foucault et al.   JOURNAL OF CLINICAL VIROLOGY

Endogenous protein C inhibits activation of coagulation and transiently lowers bacterial outgrowth in murineEscherichia coliperitonitis

(2011) M. SCHOUTEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Human Pulmonary Microvascular Endothelial Cells Support Productive Replication of Highly Pathogenic Avian Influenza Viruses: Possible Involvement in the Pathogenesis of Human H5N1 Virus Infection

(2011) H. Zeng et al.   JOURNAL OF VIROLOGY

The Multibasic Cleavage Site of the Hemagglutinin of Highly Pathogenic A/Vietnam/1203/2004 (H5N1) Avian Influenza Virus Acts as a Virulence Factor in a Host-Specific Manner in Mammals

(2011) A. L. Suguitan et al.   JOURNAL OF VIROLOGY

The TLR4-TRIF Pathway Protects against H5N1 Influenza Virus Infection

(2011) K. Shinya et al.   JOURNAL OF VIROLOGY

PAD4-Mediated Neutrophil Extracellular Trap Formation Is Not Required for Immunity against Influenza Infection

(2011) Saskia Hemmers et al.   PLoS One

Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus

(2011) K. B. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein C anticoagulant system—anti-inflammatory effects

(2011) Charles T. Esmon   Seminars in Immunopathology

Serum D-dimer changes and prognostic implication in 2009 novel influenza A(H1N1)

(2011) Z.F. Wang et al.   THROMBOSIS RESEARCH

Importance of viral genomic composition in modulating glycoprotein content on the surface of influenza virus particles

(2011) Vincent Moulès et al.   VIROLOGY

Induction and evasion of type I interferon responses by influenza viruses

(2011) Adolfo García-Sastre   VIRUS RESEARCH

Superior Immunogenicity of Inactivated Whole Virus H5N1 Influenza Vaccine is Primarily Controlled by Toll-like Receptor Signalling

(2011) Felix Geeraedts et al.   PLoS Pathogens

Differential Contribution of PB1-F2 to the Virulence of Highly Pathogenic H5N1 Influenza A Virus in Mammalian and Avian Species

(2011) Mirco Schmolke et al.   PLoS Pathogens

Highly Pathogenic Avian Influenza Virus H5N1 Infects Alveolar Macrophages without Virus Production or Excessive TNF-Alpha Induction

(2011) Debby van Riel et al.   PLoS Pathogens

The Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon at the Level of the MAVS Adaptor Protein

(2011) Zsuzsanna T. Varga et al.   PLoS Pathogens

HLA-G*0105N allele is associated with augmented risk for HIV infection in white female patients

(2010) Ludovica Segat et al.   AIDS

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

Natural Killer Cell Education and Tolerance

(2010) Mark T. Orr et al.   CELL

Emerging topics and new perspectives on HLA-G

(2010) Enrico Fainardi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inflammasomes: current understanding and open questions

(2010) Franz Bauernfeind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Clinical Course of Avian Influenza A(H5N1) in Patients at the Persahabatan Hospital, Jakarta, Indonesia, 2005–2008

(2010) Priyanti Z. Soepandi et al.   CHEST

Respective roles of TLR, RIG-I and NLRP3 in influenza virus infection and immunity: impact on vaccine design

(2010) Takeshi Ichinohe   Expert Review of Vaccines

Plasminogen deficiency

(2010) R. MEHTA et al.   HAEMOPHILIA

Induction of cell surface human leukocyte antigen–G expression in pandemic H1N1 2009 and seasonal H1N1 influenza virus–infected patients

(2010) Hai-Xiao Chen et al.   HUMAN IMMUNOLOGY

Splicing of influenza A virus NS1 mRNA is independent of the viral NS1 protein

(2010) N. C. Robb et al.   JOURNAL OF GENERAL VIROLOGY

Plasminogen promotes influenza A virus replication through an annexin 2-dependent pathway in the absence of neuraminidase

(2010) F. LeBouder et al.   JOURNAL OF GENERAL VIROLOGY

Antimicrobial activity of mucosal-associated invariant T cells

(2010) Lionel Le Bourhis et al.   NATURE IMMUNOLOGY

IL-1β Processing in Host Defense: Beyond the Inflammasomes

(2010) Mihai G. Netea et al.   PLoS Pathogens

Immunosuppressive HLA-G molecule is upregulated in alveolar epithelial cells after influenza A virus infection

(2009) Fanny LeBouder et al.   HUMAN IMMUNOLOGY

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

(2009) M. D. Tate et al.   JOURNAL OF IMMUNOLOGY

Protective Role for Protease-Activated Receptor-2 against Influenza Virus Pathogenesis via an IFN- -Dependent Pathway

(2009) K. Khoufache et al.   JOURNAL OF IMMUNOLOGY

Full Factorial Analysis of Mammalian and Avian Influenza Polymerase Subunits Suggests a Role of an Efficient Polymerase for Virus Adaptation

(2009) Olive T. W. Li et al.   PLoS One

A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection

(2009) D. Marsolais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Line of attack: NK cell specificity and integration of signals

(2008) Yenan T Bryceson et al.   CURRENT OPINION IN IMMUNOLOGY

Alveolar Macrophages Are Indispensable for Controlling Influenza Viruses in Lungs of Pigs

(2008) H. M. Kim et al.   JOURNAL OF VIROLOGY

Annexin II Incorporated into Influenza Virus Particles Supports Virus Replication by Converting Plasminogen into Plasmin

(2008) F. LeBouder et al.   JOURNAL OF VIROLOGY

Influenza Virus Infection Augments NK Cell Inhibition through Reorganization of Major Histocompatibility Complex Class I Proteins

(2008) H. Achdout et al.   JOURNAL OF VIROLOGY

Cellular Proteins in Influenza Virus Particles

(2008) Megan L. Shaw et al.   PLoS Pathogens

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens