A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

(2015) M. J. Schuijs et al.   SCIENCE

Functions of the influenza A virus NS1 protein in antiviral defense

(2015) Robert M Krug   Current Opinion in Virology

Long-term survival of influenza virus infected club cells drives immunopathology

(2014) Nicholas S. Heaton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Highly pathogenic avian influenza A H5N1 and pandemic H1N1 virus infections have different phenotypes in Toll-like receptor 3 knockout mice

(2014) Y. H. C. Leung et al.   JOURNAL OF GENERAL VIROLOGY

CCR2+ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality

(2014) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Tissue damage control in disease tolerance

(2014) Miguel P. Soares et al.   TRENDS IN IMMUNOLOGY

Visualizing the Beta Interferon Response in Mice during Infection with Influenza A Viruses Expressing or Lacking Nonstructural Protein 1

(2013) C. Kallfass et al.   JOURNAL OF VIROLOGY

Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections

(2013) M Guilliams et al.   Mucosal Immunology

Biological features of novel avian influenza A (H7N9) virus

(2013) Jianfang Zhou et al.   NATURE

M2e-Displaying Virus-Like Particles with Associated RNA Promote T Helper 1 Type Adaptive Immunity against Influenza A

(2013) Lorena Itatí Ibañez et al.   PLoS One

A20 in inflammation and autoimmunity

(2013) Leen Catrysse et al.   TRENDS IN IMMUNOLOGY

Role of T cell immunity in recovery from influenza virus infection

(2013) Jie Sun et al.   Current Opinion in Virology

Clearance of influenza virus infections by T cells: risk of collateral damage?

(2013) MLB Hillaire et al.   Current Opinion in Virology

Disease Tolerance as a Defense Strategy

(2012) R. Medzhitov et al.   SCIENCE

A20 (Tnfaip3) Deficiency in Myeloid Cells Protects against Influenza A Virus Infection

(2012) Jonathan Maelfait et al.   PLoS Pathogens

The Airway Epithelium: Soldier in the Fight against Respiratory Viruses

(2011) M. Vareille et al.   CLINICAL MICROBIOLOGY REVIEWS

Pivotal Advance: Invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune-pathology during severe influenza A virus infection

(2011) Wai Ling Kok et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Responses of Mouse Airway Epithelial Cells and Alveolar Macrophages to Virulent and Avirulent Strains of Influenza A Virus

(2011) Michelle D. Tate et al.   VIRAL IMMUNOLOGY

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

The Clara cell: a "Third Reich eponym"?

(2010) A. Winkelmann et al.   EUROPEAN RESPIRATORY JOURNAL

TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases

(2010) Kislay Parvatiyar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis

(2010) Lars Vereecke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

(2010) Jodi McGill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antiviral CD8+T cell effector activities in situ are regulated by target cell type

(2010) Matthew M. Hufford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of inflammatory and antiviral signaling by A20

(2010) Kislay Parvatiyar et al.   MICROBES AND INFECTION

Influenza virus activates inflammasomes via its intracellular M2 ion channel

(2010) Takeshi Ichinohe et al.   NATURE IMMUNOLOGY

Epithelial decision makers: in search of the 'epimmunome'

(2010) Mahima Swamy et al.   NATURE IMMUNOLOGY

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

(2010) A. Baum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MCP-1 Antibody Treatment Enhances Damage and Impedes Repair of the Alveolar Epithelium in Influenza Pneumonitis

(2009) T. Narasaraju et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10

(2009) Jie Sun et al.   NATURE MEDICINE

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

(2009) C. R. Baskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection

(2009) J. R. Aldridge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lethal Influenza Virus Infection in Macaques Is Associated with Early Dysregulation of Inflammatory Related Genes

(2009) Cristian Cillóniz et al.   PLoS Pathogens

Conditional Expression of Genes in the Respiratory Epithelium in Transgenic Mice

(2008) Anne-Karina Perl et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand

(2008) Susanne Herold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20

(2008) Emre E. Turer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE