Nacre extract from pearl oyster attenuates amyloid beta-induced memory impairment

Chronic administration of Tat-GluR23Y ameliorates cognitive dysfunction targeting CREB signaling in rats with amyloid beta neurotoxicity

(2021) Fatemeh Ashourpour et al.   METABOLIC BRAIN DISEASE

Involvement of Cholinergic, Adrenergic, and Glutamatergic Network Modulation with Cognitive Dysfunction in Alzheimer’s Disease

(2021) Yu-Jung Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sanweidoukou Decoction, a Chinese herbal formula, ameliorates β-amyloid protein-induced neuronal insult via modulating MAPK/NF-κB signaling pathways: studies in vivo and in vitro

(2021) Feng-mao An et al.   JOURNAL OF ETHNOPHARMACOLOGY

Roflumilast and tadalafil improve learning and memory deficits in intracerebroventricular Aβ1–42 rat model of Alzheimer’s disease through modulations of hippocampal cAMP/cGMP/BDNF signaling pathway

(2021) Noorul Hasan et al.   Pharmacological Reports

Sulfated Polysaccharide Isolated from the Nacre of Pearl Oyster Improves Scopolamine-Induced Memory Impairment

(2021) Hikaru Yamagami et al.   Antioxidants

Bolstered Neuronal Antioxidant Response May Confer Resistance to Development of Dementia in Individuals with Alzheimer's Neuropathology by Ameliorating Amyloid-β-Induced Oxidative Stress

(2021) Ryan D. Hallam   JOURNAL OF NEUROSCIENCE

The protective and therapeutic effects of vinpocetine, a PDE1 inhibitor, on oxidative stress and learning and memory impairment induced by an intracerebroventricular (ICV) injection of amyloid beta (aβ) peptide

(2020) Meysam Shekarian et al.   BEHAVIOURAL BRAIN RESEARCH

GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route

(2020) Erika Di Biase et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease

(2020) Tiantian Guo et al.   Molecular Neurodegeneration

Estrogens Inhibit Amyloid-β-Mediated Paired Helical Filament-Like Conformation of Tau Through Antioxidant Activity and miRNA 218 Regulation in hTau Mice

(2020) Michela Guglielmotto et al.   JOURNAL OF ALZHEIMERS DISEASE

The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease

(2020) Meysam Amidfar et al.   LIFE SCIENCES

Blood-Brain Barrier Permeable Chitosan Oligosaccharides Interfere with β-Amyloid Aggregation and Alleviate β-Amyloid Protein Mediated Neurotoxicity and Neuroinflammation in a Dose- and Degree of Polymerization-Dependent Manner

(2020) Limeng Zhu et al.   Marine Drugs

Memantine treatment exerts an antidepressant-like effect by preventing hippocampal mitochondrial dysfunction and memory impairment via upregulation of CREB/BDNF signaling in the rat model of chronic unpredictable stress-induced depression

(2020) Sandeep K. Mishra et al.   NEUROCHEMISTRY INTERNATIONAL

Executive Functions in Alzheimer Disease: A Systematic Review

(2019) Angela Guarino et al.   Frontiers in Aging Neuroscience

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

(2019) D. Allan Butterfield et al.   NATURE REVIEWS NEUROSCIENCE

Pinus halepensis essential oil attenuates the toxic Alzheimer’s amyloid beta (1-42)-induced memory impairment and oxidative stress in the rat hippocampus

(2019) Paula Alexandra Postu et al.   BIOMEDICINE & PHARMACOTHERAPY

Nanoscaled pearl powder accelerates wound repair and regeneration in vitro and in vivo

(2019) Xi Chen et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Initiated by CREB: Resolving Gene Regulatory Programs in Learning and Memory

(2019) Jenifer C. Kaldun et al.   BIOESSAYS

Angelica polysaccharide ameliorates memory impairment in Alzheimer’s disease rat through activating BDNF/TrkB/CREB pathway

(2019) Qian Du et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Alzheimer’s Disease and Parkinson’s Disease: A Nutritional Toxicology Perspective of the Impact of Oxidative Stress, Mitochondrial Dysfunction, Nutrigenomics and Environmental Chemicals

(2019) Aayushi Agnihotri et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Efficacy of protein rich pearl powder on antioxidant status in a randomized placebo-controlled trial

(2018) Hui-Fang Chiu et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer’s Rat Model

(2018) CHONGYUN WU et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Tau-targeting therapies for Alzheimer disease

(2018) Erin E. Congdon et al.   Nature Reviews Neurology

Nacre extract prevents scopolamine-induced memory deficits in rodents

(2018) Yasushi Hasegawa et al.   Asian Pacific Journal of Tropical Medicine

Immediate Early Genes, Memory and Psychiatric Disorders: Focus on c-Fos, Egr1 and Arc

(2018) Francisco T. Gallo et al.   Frontiers in Behavioral Neuroscience

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

Mini-GAGR, an intranasally applied polysaccharide, activates the neuronal Nrf2-mediated antioxidant defense system

(2018) Kelsey Murphy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The DNA repair associated protein Gadd45׆ regulates the temporal coding of immediate early gene expression within the prelimbic prefrontal cortex and is required for the consolidation of associative fear memory

(2018) Xiang Li et al.   JOURNAL OF NEUROSCIENCE

Fucosterol from an Edible Brown Alga Ecklonia stolonifera Prevents Soluble Amyloid Beta-Induced Cognitive Dysfunction in Aging Rats

(2018) Jeong Oh et al.   Marine Drugs

Mouse Models of Alzheimer’s Disease

(2017) Gisela Esquerda-Canals et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Acyl ghrelin improves cognition, synaptic plasticity deficits and neuroinflammation following amyloid β (Aβ1-40) administration in mice

(2017) V. V. Santos et al.   JOURNAL OF NEUROENDOCRINOLOGY

Studies for Improving a Rat Model of Alzheimer’s Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory

(2017) Ágnes Kasza et al.   MOLECULES

Protective effects of gingerol on streptozotocin-induced sporadic Alzheimer’s disease: emphasis on inhibition of β-amyloid, COX-2, alpha-, beta - secretases and APH1a

(2017) Ali M. El Halawany et al.   Scientific Reports

The Cholinergic System Modulates Memory and Hippocampal Plasticity via Its Interactions with Non-Neuronal Cells

(2017) Sara V. Maurer et al.   Frontiers in Immunology

Impaired Resolution of Inflammation in Alzheimer’s Disease: A Review

(2017) Robert A. Whittington et al.   Frontiers in Immunology

Anticonvulsant and sedative–hypnotic activity screening of pearl and nacre (mother of pearl)

(2016) Jing-Xian Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

GPR40 receptor activation leads to CREB phosphorylation and improves cognitive performance in an Alzheimer’s disease mouse model

(2016) Muhammad Zahid Khan et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Effects of scallop shell extract on scopolamine-induced memory impairment and MK801-induced locomotor activity

(2016) Yasushi Hasegawa et al.   Asian Pacific Journal of Tropical Medicine

Nacre extract restores the mineralization capacity of subchondral osteoarthritis osteoblasts

(2015) A. Brion et al.   JOURNAL OF STRUCTURAL BIOLOGY

Central acylated ghrelin improves memory function and hippocampal AMPK activation and partly reverses the impairment of energy and glucose metabolism in rats infused with β-amyloid

(2015) Suna Kang et al.   PEPTIDES

Nacre-driven water-soluble factors promote wound healing of the deep burn porcine skin by recovering angiogenesis and fibroblast function

(2011) Kyunghee Lee et al.   MOLECULAR BIOLOGY REPORTS

Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons

(2011) Subbiah Pugazhenthi et al.   Molecular Neurodegeneration

Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease

(2009) S. Peng et al.   JOURNAL OF NEUROSCIENCE