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Title
Cholesterol metabolism: from lipidomics to immunology
Authors
Keywords
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Journal
JOURNAL OF LIPID RESEARCH
Volume 63, Issue 2, Pages 100165
Publisher
Elsevier BV
Online
2021-12-22
DOI
10.1016/j.jlr.2021.100165
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Note: Only part of the references are listed.- Deep mining of oxysterols and cholestenoic acids in human plasma and cerebrospinal fluid: Quantification using isotope dilution mass spectrometry
- (2021) Eylan Yutuc et al. ANALYTICA CHIMICA ACTA
- Identification of Anti-Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Oxysterol Derivatives In Vitro
- (2021) Hirofumi Ohashi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2021) Imen Ghzaiel et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm
- (2021) Hyelim Kim et al. Nano Today
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- (2021) Jane E. Potter et al. Orphanet Journal of Rare Diseases
- Oxysterols protect bovine endometrial cells against pore‐forming toxins from pathogenic bacteria
- (2021) Thomas J. R. Ormsby et al. FASEB JOURNAL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
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- (2020) Annsea Park et al. Cell Host & Microbe
- Cholestane-3β, 5α, 6β-triol: Further insights into the performance of this oxysterol in diagnosis of Niemann-Pick disease type C
- (2020) J.A. Cooper et al. MOLECULAR GENETICS AND METABOLISM
- SARS-CoV-2 productively infects human gut enterocytes
- (2020) Mart M. Lamers et al. SCIENCE
- Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol
- (2020) Michael E. Abrams et al. Nature Microbiology
- Coronavirus membrane fusion mechanism offers a potential target for antiviral development
- (2020) Tiffany Tang et al. ANTIVIRAL RESEARCH
- Aster proteins regulate the accessible cholesterol pool in the plasma membrane
- (2020) Alessandra Ferrari et al. MOLECULAR AND CELLULAR BIOLOGY
- Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins
- (2020) Quan D. Zhou et al. NATURE IMMUNOLOGY
- Cholesterol in quarantine
- (2020) Eric V. Dang et al. NATURE IMMUNOLOGY
- Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine
- (2020) Michael N. Trinh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)
- (2020) Shuofeng Yuan et al. Viruses-Basel
- THE CHOLESTEROL METABOLITE 27-HYDROXYCHOLESTEROL INHIBITS SARS-CoV-2 AND IS MARKEDLY DECREASED IN COVID-19 PATIENTS
- (2020) Alessandro Marcello et al. Redox Biology
- 25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor
- (2020) Shulong Zu et al. CELL RESEARCH
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- (2020) Shaobo Wang et al. EMBO JOURNAL
- Active cholesterol 20 years on
- (2020) Yvonne Lange et al. TRAFFIC
- Cholesterol access in cellular membranes controls Hedgehog signaling
- (2020) Arun Radhakrishnan et al. Nature Chemical Biology
- Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion
- (2020) Ruochen Zang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates
- (2020) Jonas Abdel-Khalik et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis
- (2019) Annika Wyss et al. Mucosal Immunology
- Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders
- (2019) William J. Griffiths et al. FREE RADICAL BIOLOGY AND MEDICINE
- Elevated oxysterol levels in human and mouse livers reflect non-alcoholic steatohepatitis
- (2019) Tina Raselli et al. JOURNAL OF LIPID RESEARCH
- 11β-hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor gamma
- (2019) Katharina R. Beck et al. JOURNAL OF LIPID RESEARCH
- Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2
- (2019) Katharina R. Beck et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Mining for Oxysterols in Cyp7b1−/− Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5
- (2019) Anna Meljon et al. Biomolecules
- Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing
- (2019) Liang Chen et al. JOURNAL OF LIPID RESEARCH
- Ostreolysin A and anthrolysin O use different mechanisms to control movement of cholesterol from the plasma membrane to the endoplasmic reticulum
- (2019) Kristen A. Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Movement of accessible plasma membrane cholesterol by the GRAMD1 lipid transfer protein complex
- (2019) Tomoki Naito et al. eLife
- Oxysterols as lipid mediators: Their biosynthetic genes, enzymes and metabolites
- (2019) William J. Griffiths et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Identification of 7α,24-dihydroxy-3-oxocholest-4-en-26-oic and 7α,25-dihydroxy-3-oxocholest-4-en-26-oic acids in human cerebrospinal fluid and plasma
- (2018) Jonas Abdel-Khalik et al. BIOCHIMIE
- Lysosomal Cholesterol Hydrolysis Couples Efferocytosis to Anti-Inflammatory Oxysterol ProductionNovelty and Significance
- (2018) Manon Viaud et al. CIRCULATION RESEARCH
- Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation
- (2018) Johanna Emgård et al. IMMUNITY
- EBI2 in splenic and local immune responses and in autoimmunity
- (2018) L. Barington et al. JOURNAL OF LEUKOCYTE BIOLOGY
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- (2018) William J. Griffiths et al. JOURNAL OF LIPID RESEARCH
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- (2018) Eric V Dang et al. CURRENT OPINION IN IMMUNOLOGY
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- (2017) Rodney Elwood Infante et al. eLife
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- (2017) Valeria Cagno et al. Redox Biology
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- (2016) Peter J. Crick et al. MOLECULAR NEUROBIOLOGY
- Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells
- (2015) Fabio R. Santori et al. Cell Metabolism
- Oxysterols regulate encephalitogenic CD4+ T cell trafficking during central nervous system autoimmunity
- (2015) F. Chalmin et al. JOURNAL OF AUTOIMMUNITY
- Sterol metabolism controls T H 17 differentiation by generating endogenous RORγ agonists
- (2015) Xiao Hu et al. Nature Chemical Biology
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- The oxysterol and cholestenoic acid profile of mouse cerebrospinal fluid
- (2015) Peter J. Crick et al. STEROIDS
- Transcriptional regulation and functional characterization of the oxysterol/EBI2 system in primary human macrophages
- (2014) Inga Preuss et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Wolman disease associated with hemophagocytic lymphohistiocytosis: attempts for an explanation
- (2014) Roberta Taurisano et al. EUROPEAN JOURNAL OF PEDIATRICS
- EBI2 regulates intracellular signaling and migration in human astrocyte
- (2014) Aleksandra Rutkowska et al. GLIA
- Cholestenoic acids regulate motor neuron survival via liver X receptors
- (2014) Spyridon Theofilopoulos et al. JOURNAL OF CLINICAL INVESTIGATION
- Liver disease in infancy caused by oxysterol 7α-hydroxylase deficiency: successful treatment with chenodeoxycholic acid
- (2014) Dongling Dai et al. JOURNAL OF INHERITED METABOLIC DISEASE
- On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO
- (2014) Ingemar Björkhem et al. JOURNAL OF LIPID RESEARCH
- Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels
- (2014) A. R. Stiles et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oxysterols are agonist ligands of ROR t and drive Th17 cell differentiation
- (2014) P. Soroosh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 25-Hydroxycholesterol acts as an amplifier of inflammatory signaling
- (2014) E. S. Gold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon
- (2014) A. Reboldi et al. SCIENCE
- Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol
- (2014) Andrea Civra et al. Scientific Reports
- Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis
- (2014) Akash Das et al. eLife
- 11β-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo
- (2013) Tijana Mitić et al. BIOCHEMICAL PHARMACOLOGY
- The role of interferon-β in the treatment of multiple sclerosis and experimental autoimmune encephalomyelitis - in the perspective of inflammasomes
- (2013) Makoto Inoue et al. IMMUNOLOGY
- The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells
- (2013) Dominique Gatto et al. NATURE IMMUNOLOGY
- The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
- (2013) Gautier Koscielny et al. NUCLEIC ACIDS RESEARCH
- Use of mutant 125I-Perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells
- (2013) A. Das et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EBI2-mediated bridging channel positioning supports splenic dendritic cell homeostasis and particulate antigen capture
- (2013) Tangsheng Yi et al. eLife
- Oxysterols in the pathogenesis of major chronic diseases
- (2013) Giuseppe Poli et al. Redox Biology
- Oxysterol Gradient Generation by Lymphoid Stromal Cells Guides Activated B Cell Movement during Humoral Responses
- (2012) Tangsheng Yi et al. IMMUNITY
- Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol
- (2012) Su-Yang Liu et al. IMMUNITY
- The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response
- (2012) Mathieu Blanc et al. IMMUNITY
- Systematic identification of type I and type II interferon-induced antiviral factors
- (2012) S.-Y. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 25-hydroxycholesterol enhances cytokine release and toll-like receptor 3 response in airway epithelial cells
- (2012) Akira Koarai et al. RESPIRATORY RESEARCH
- 27-Hydroxycholesterol, does it exist? On the nomenclature and stereochemistry of 26-hydroxylated sterols
- (2012) Robert J. Fakheri et al. STEROIDS
- Pathways of cholesterol oxidation via non-enzymatic mechanisms
- (2011) Luigi Iuliano CHEMISTRY AND PHYSICS OF LIPIDS
- Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
- (2011) Greta Guarda et al. IMMUNITY
- Listeria monocytogenesInfection Induces Prosurvival Metabolic Signaling in Macrophages
- (2011) Tie Zou et al. INFECTION AND IMMUNITY
- Conversion of 7-Dehydrocholesterol to 7-Ketocholesterol Is Catalyzed by Human Cytochrome P450 7A1 and Occurs by Direct Oxidation without an Epoxide Intermediate
- (2011) Raku Shinkyo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Disorders of bile acid synthesis
- (2011) Peter Theodore Clayton JOURNAL OF INHERITED METABOLIC DISEASE
- Cholesterol 25-hydroxylation activity of CYP3A
- (2011) Akira Honda et al. JOURNAL OF LIPID RESEARCH
- Oxysterols direct B-cell migration through EBI2
- (2011) Changlu Liu et al. NATURE
- Oxysterols direct immune cell migration via EBI2
- (2011) Sébastien Hannedouche et al. NATURE
- Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis
- (2011) Mathieu Blanc et al. PLOS BIOLOGY
- A second class of nuclear receptors for oxysterols: Regulation of RORα and RORγ activity by 24S-hydroxycholesterol (cerebrosterol)
- (2010) Yongjun Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
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- (2010) Edward A. Dennis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Editorial: 25-Hydroxycholesterol: a new life in immunology
- (2010) Jeffrey G. McDonald et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons
- (2010) Kiwon Park et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
- (2010) Katrin Düvel et al. MOLECULAR CELL
- Structural Basis for Hydroxycholesterols as Natural Ligands of Orphan Nuclear Receptor RORγ
- (2010) Lihua Jin et al. MOLECULAR ENDOCRINOLOGY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
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- (2010) P. de Medina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes
- (2010) Josef Ecker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stimulation of Cholesterol Efflux by LXR Agonists in Cholesterol-Loaded Human Macrophages Is ABCA1-Dependent but ABCG1-Independent
- (2009) Sandra Larrede et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol
- (2009) Hyock Joo Kwon et al. CELL
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- (2009) Vesa M. Olkkonen et al. MOLECULAR ASPECTS OF MEDICINE
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- (2009) João P. Pereira et al. NATURE
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- (2009) D. R. Bauman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance
- (2008) Arun Radhakrishnan et al. Cell Metabolism
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- (2008) Thomas Porstmann et al. Cell Metabolism
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- Cholesterol homeostasis and the escape tendency (activity) of plasma membrane cholesterol
- (2008) Yvonne Lange et al. PROGRESS IN LIPID RESEARCH
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