Reduced Plasma Levels of 25-Hydroxycholesterol and Increased Cerebrospinal Fluid Levels of Bile Acid Precursors in Multiple Sclerosis Patients

Nuclear Receptor NR1H3 in Familial Multiple Sclerosis

(2016) Zhe Wang et al.   NEURON

Oxysterols regulate encephalitogenic CD4+ T cell trafficking during central nervous system autoimmunity

(2015) F. Chalmin et al.   JOURNAL OF AUTOIMMUNITY

Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum

(2015) Delphine Meffre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Charge-Tags for Sterol and Oxysterol Analysis

(2014) P. J. Crick et al.   CLINICAL CHEMISTRY

Cholestenoic acids regulate motor neuron survival via liver X receptors

(2014) Spyridon Theofilopoulos et al.   JOURNAL OF CLINICAL INVESTIGATION

Liver X receptors in lipid metabolism: opportunities for drug discovery

(2014) Cynthia Hong et al.   NATURE REVIEWS DRUG DISCOVERY

Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

(2014) Manuel A. Friese et al.   Nature Reviews Neurology

Oxysterols are agonist ligands of ROR t and drive Th17 cell differentiation

(2014) P. Soroosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon

(2014) A. Reboldi et al.   SCIENCE

The role of interferon-β in the treatment of multiple sclerosis and experimental autoimmune encephalomyelitis - in the perspective of inflammasomes

(2013) Makoto Inoue et al.   IMMUNOLOGY

7α-hydroxy-3-oxo-4-cholestenoic acid in cerebrospinal fluid reflects the integrity of the blood-brain barrier

(2013) Ahmed Saeed et al.   JOURNAL OF LIPID RESEARCH

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Sterols and oxysterols in immune cell function

(2013) Nathanael J Spann et al.   NATURE IMMUNOLOGY

Oxysterols and Parkinson's disease: Evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease

(2013) Ingemar Björkhem et al.   NEUROSCIENCE LETTERS

Five decades with oxysterols

(2012) Ingemar Björkhem   BIOCHIMIE

Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol

(2012) Su-Yang Liu et al.   IMMUNITY

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

(2012) Mathieu Blanc et al.   IMMUNITY

Oxysterols direct B-cell migration through EBI2

(2011) Changlu Liu et al.   NATURE

Oxysterols direct immune cell migration via EBI2

(2011) Sébastien Hannedouche et al.   NATURE

A second class of nuclear receptors for oxysterols: Regulation of RORα and RORγ activity by 24S-hydroxycholesterol (cerebrosterol)

(2010) Yongjun Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Editorial: 25-Hydroxycholesterol: a new life in immunology

(2010) Jeffrey G. McDonald et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons

(2010) Kiwon Park et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Multiple sclerosis: risk factors, prodromes, and potential causal pathways

(2010) Sreeram V Ramagopalan et al.   LANCET NEUROLOGY

Cerebrospinal Fluid Steroidomics: Are Bioactive Bile Acids Present in Brain?

(2009) Michael Ogundare et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide

(2009) Ulf Diczfalusy et al.   JOURNAL OF LIPID RESEARCH

Oxysterols and neurodegenerative diseases

(2009) Ingemar Björkhem et al.   MOLECULAR ASPECTS OF MEDICINE

Multiple sclerosis immunology: The healthy immune system vs the MS immune system

(2009) L. H. Kasper et al.   NEUROLOGY

Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease

(2009) Alina Solomon et al.   NEUROSCIENCE LETTERS

25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production

(2009) D. R. Bauman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Different Patterns of Oxidized Lipid Products in Plasma and Urine of Dengue Fever, Stroke, and Parkinson's Disease Patients: Cautions in the Use of Biomarkers of Oxidative Stress

(2008) Chung-Yung J. Lee et al.   ANTIOXIDANTS & REDOX SIGNALING