Macrophage polarization state affects lipid composition and the channeling of exogenous fatty acids into endogenous lipid pools

Diet-regulated production of PDGFcc by macrophages controls energy storage

(2021) Nehemiah Cox et al.   SCIENCE

New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages

(2020) Ana Batista-Gonzalez et al.   Frontiers in Immunology

Cell‐intrinsic metabolic regulation of mononuclear phagocyte activation: Findings from the tip of the iceberg

(2020) Nikki Teijlingen Bakker et al.   IMMUNOLOGICAL REVIEWS

Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome

(2020) Wei-Yuan Hsieh et al.   Cell Metabolism

Determinants of Resident Tissue Macrophage Identity and Function

(2020) Camille Blériot et al.   IMMUNITY

Triacylglycerol synthesis enhances macrophage inflammatory function

(2020) Angela Castoldi et al.   Nature Communications

Plasmalogens: A potential therapeutic target for neurodegenerative and cardiometabolic disease

(2019) Sudip Paul et al.   PROGRESS IN LIPID RESEARCH

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

(2019) Diego Adhemar Jaitin et al.   CELL

Neuroendocrine Regulation of Energy Metabolism Involving Different Types of Adipose Tissues

(2019) Qi Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting a ceramide double bond improves insulin resistance and hepatic steatosis

(2019) Bhagirath Chaurasia et al.   SCIENCE

The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state

(2019) Leanne Hodson et al.   Nature Reviews Endocrinology

Western Diet and the Immune System: An Inflammatory Connection

(2019) Anette Christ et al.   IMMUNITY

Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase

(2019) Mario A. Lauterbach et al.   IMMUNITY

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism

(2018) Graeme I. Lancaster et al.   Cell Metabolism

Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue

(2018) David A. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sphingolipids and their metabolism in physiology and disease

(2017) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

(2015) Rachel J. Perry et al.   CELL

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

Macrophage-specificde NovoSynthesis of Ceramide Is Dispensable for Inflammasome-driven Inflammation and Insulin Resistance in Obesity

(2015) Christina D. Camell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ceramides – Lipotoxic Inducers of Metabolic Disorders

(2015) Bhagirath Chaurasia et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

(2014) Stanley Ching-Cheng Huang et al.   NATURE IMMUNOLOGY

In Vivo Profiling and Visualization of Cellular Protein-Lipid Interactions Using Bifunctional Fatty Acids

(2013) Per Haberkant et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Plasma lipid profiling in a large population-based cohort

(2013) Jacquelyn M. Weir et al.   JOURNAL OF LIPID RESEARCH

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice

(2011) Xavier Prieur et al.   DIABETES

Specificity of eicosanoid production depends on the TLR-4-stimulated macrophage phenotype

(2011) Paul C. Norris et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

(2011) Khoa D. Nguyen et al.   NATURE

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

A Mouse Macrophage Lipidome

(2010) Edward A. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation

(2010) Suneil K. Koliwad et al.   JOURNAL OF CLINICAL INVESTIGATION

Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

(2010) Aliki Kosteli et al.   JOURNAL OF CLINICAL INVESTIGATION