Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue

Elevating adipose eosinophils in obese mice to physiologically normal levels does not rescue metabolic impairments

(2018) W. Reid Bolus et al.   Molecular Metabolism

Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity

(2017) Anthony T. Phan et al.   IMMUNITY

Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice

(2017) Raymond E. Soccio et al.   JOURNAL OF CLINICAL INVESTIGATION

Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo

(2017) Lars L. P. Hanssen et al.   NATURE CELL BIOLOGY

Mechanisms, Pathophysiology, and Management of Obesity

(2017) Steven B. Heymsfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synergistic Modulation of Inflammatory but not Metabolic Effects of High-Fat Feeding by CCR2 and CX3CR1

(2017) Hanrui Zhang et al.   Obesity

CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors

(2017) Allah Nawaz et al.   Nature Communications

Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity

(2017) Brittney R. Coats et al.   Cell Reports

Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice

(2016) Brian F. Zamarron et al.   DIABETES

Local proliferation initiates macrophage accumulation in adipose tissue during obesity

(2016) C Zheng et al.   Cell Death & Disease

Type 2 responses at the interface between immunity and fat metabolism

(2015) Justin I Odegaard et al.   CURRENT OPINION IN IMMUNOLOGY

CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity

(2015) David L. Morris et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue

(2015) W. R. Bolus et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Activation of NF-κB drives the enhanced survival of adipose tissue macrophages in an obesogenic environment

(2015) Andrea A. Hill et al.   Molecular Metabolism

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation

(2014) Shinya U. Amano et al.   Cell Metabolism

Epigenomics of macrophages

(2014) David Gosselin et al.   IMMUNOLOGICAL REVIEWS

Control of Adipose Tissue Expandability in Response to High Fat Diet by the Insulin-like Growth Factor-binding Protein-4

(2014) Olga Gealekman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An MHC II-Dependent Activation Loop between Adipose Tissue Macrophages and CD4+ T Cells Controls Obesity-Induced Inflammation

(2014) Kae Won Cho et al.   Cell Reports

From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation

(2014) Paola Italiani et al.   Frontiers in Immunology

Adipose tissue angiogenesis: Impact on obesity and type-2 diabetes

(2013) Silvia Corvera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

(2013) Xiaoyuan Xu et al.   Cell Metabolism

Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration

(2013) Yun-Hee Lee et al.   Cell Metabolism

The DNA-binding factor Ctcf critically controls gene expression in macrophages

(2013) Tatjana Nikolic et al.   Cellular & Molecular Immunology

Local proliferation of macrophages in adipose tissue during obesity-induced inflammation

(2013) Julia Haase et al.   DIABETOLOGIA

Macrophages, fat, and the emergence of immunometabolism

(2013) Anthony W. Ferrante   JOURNAL OF CLINICAL INVESTIGATION

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

CXCR3 modulates obesity-induced visceral adipose inflammation and systemic insulin resistance

(2013) Jeffrey A. Deiuliis et al.   Obesity

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Clodronate Liposomes Improve Metabolic Profile and Reduce Visceral Adipose Macrophage Content in Diet-Induced Obese Mice

(2011) Bin Feng et al.   PLoS One

Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation

(2011) M. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Functional Heterogeneity of CD11c-positive Adipose Tissue Macrophages in Diet-induced Obese Mice

(2010) Pingping Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesity

(2010) Olga T. Hardy et al.   Surgery for Obesity and Related Diseases

Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals

(2008) David Patsouris et al.   Cell Metabolism