Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity
Published 2021 View Full Article
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Title
Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity
Authors
Keywords
COVID19, spike, nucleocapsid, exosome, mRNA, cationic lipid, lipofection, antibody, T-cell, extracellular vesicles
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 297, Issue 5, Pages 101266
Publisher
Elsevier BV
Online
2021-10-01
DOI
10.1016/j.jbc.2021.101266
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Note: Only part of the references are listed.- Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections
- (2021) Ben M. Flude et al. Viruses-Basel
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- (2021) Jerald Sadoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection
- (2021) Leonidas Stamatatos et al. SCIENCE
- Immunogenicity and efficacy of mRNA COVID-19 vaccine MRT5500 in preclinical animal models
- (2021) Kirill V. Kalnin et al. npj Vaccines
- Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum
- (2021) Chang Liu et al. CELL
- Lipids and Lipid Derivatives for RNA Delivery
- (2021) Yuebao Zhang et al. CHEMICAL REVIEWS
- Choice of selectable marker affects recombinant protein expression in cells and exosomes
- (2021) Chenxu Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: Nucleocapsid Vaccine Elicits Spike-Independent SARS-CoV-2 Protective Immunity
- (2021) William E. Matchett et al. JOURNAL OF IMMUNOLOGY
- Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant
- (2021) Jamie Lopez Bernal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery
- (2021) Michael Segel et al. SCIENCE
- Combining spike- and nucleocapsid-based vaccines improves distal control of SARS-CoV-2
- (2021) Tanushree Dangi et al. Cell Reports
- Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China
- (2020) Dawei Wang et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- No flow through the vitreous humor: How strong is the evidence?
- (2020) David W. Smith et al. PROGRESS IN RETINAL AND EYE RESEARCH
- The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
- (2020) Nature Microbiology
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area
- (2020) Safiya Richardson et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Detection of Nucleocapsid Antibody to SARS-CoV-2 is More Sensitive than Antibody to Spike Protein in COVID-19 Patients
- (2020) Peter D Burbelo et al. JOURNAL OF INFECTIOUS DISEASES
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
- (2020) Markus Hoffmann et al. MOLECULAR CELL
- Mild or Moderate Covid-19
- (2020) Rajesh T. Gandhi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)
- (2020) Tao Guo et al. JAMA Cardiology
- Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates
- (2020) Kizzmekia S. Corbett et al. NEW ENGLAND JOURNAL OF MEDICINE
- An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
- (2020) Lisa A. Jackson et al. NEW ENGLAND JOURNAL OF MEDICINE
- How does SARS-CoV-2 cause COVID-19?
- (2020) Nicholas J. Matheson et al. SCIENCE
- Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity
- (2020) Carolyn Rydyznski Moderbacher et al. CELL
- Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection
- (2020) Gustavo Lou et al. JOURNAL OF CONTROLLED RELEASE
- Neuropilin-1 is a host factor for SARS-CoV-2 infection
- (2020) James L. Daly et al. SCIENCE
- Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity
- (2020) Ludovico Cantuti-Castelvetri et al. SCIENCE
- Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
- (2020) Merryn Voysey et al. LANCET
- Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
- (2020) Lindsey R. Baden et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- (2020) Fernando P. Polack et al. NEW ENGLAND JOURNAL OF MEDICINE
- mRNA: A Novel Avenue to Antibody Therapy?
- (2019) Thomas Schlake et al. MOLECULAR THERAPY
- Reassessment of Exosome Composition
- (2019) Dennis K. Jeppesen et al. CELL
- Advances in therapeutic applications of extracellular vesicles
- (2019) Oscar P. B. Wiklander et al. Science Translational Medicine
- Exosomes
- (2019) D. Michiel Pegtel et al. Annual Review of Biochemistry
- The biology of extracellular vesicles: The known unknowns
- (2019) Leonid Margolis et al. PLOS BIOLOGY
- Distinct Subcellular Compartments of Dendritic Cells Used for Cross-Presentation
- (2019) Jun Imai et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation
- (2018) Haiying Zhang et al. NATURE CELL BIOLOGY
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- (2017) Richard K. Fisher et al. JOURNAL OF SURGICAL RESEARCH
- Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
- (2017) Sushrut Kamerkar et al. NATURE
- Red-shifted luciferase–luciferin pairs for enhanced bioluminescence imaging
- (2017) Hsien-Wei Yeh et al. NATURE METHODS
- Coding and noncoding landscape of extracellular RNA released by human glioma stem cells
- (2017) Zhiyun Wei et al. Nature Communications
- Transforming Nanomedicines From Lab Scale Production to Novel Clinical Modality
- (2016) Dalit Landesman-Milo et al. BIOCONJUGATE CHEMISTRY
- Self-organization of nucleic acids in lipid constructs
- (2016) Minjee Kang et al. CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
- Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model
- (2016) Ling Li et al. HEPATOLOGY
- A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo
- (2016) Jun Chu et al. NATURE BIOTECHNOLOGY
- Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
- (2013) Lior Zangi et al. NATURE BIOTECHNOLOGY
- Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles
- (2012) Dan Peer ADVANCED DRUG DELIVERY REVIEWS
- Adenoviral Vector Immunity: Its Implications and Circumvention Strategies
- (2011) Yadvinder S. Ahi et al. CURRENT GENE THERAPY
- Progress and Prospects: prospects of repeated pulmonary administration of viral vectors
- (2009) P L Sinn et al. GENE THERAPY
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