Heat Shock Protein 60 Restricts Release of Mitochondrial dsRNA to Suppress Hepatic Inflammation and Ameliorate Non-Alcoholic Fatty Liver Disease in Mice

Mitochondrial Metabolism in the Intestinal Stem Cell Niche—Sensing and Signaling in Health and Disease

(2021) Elisabeth Urbauer et al.   Frontiers in Cell and Developmental Biology

Hypoxia-Driven Effects in Cancer: Characterization, Mechanisms, and Therapeutic Implications

(2021) Rachel Shi et al.   Cells

Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis

(2021) Shogo Kawaguchi et al.   INFLAMMATION

Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder

(2021) Guoqing Zhang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mitochondrial RNA , a new trigger of the innate immune system

(2021) Joanna Grochowska et al.   Wiley Interdisciplinary Reviews-RNA

Mitochondrial Protein Abundance Gradients Require the Distribution of Separated Mitochondria

(2021) Franziska Bollmann et al.   Biology-Basel

MAFLD: A consensus-driven proposed nomenclature for metabolic associated fatty liver disease

(2020) Mohammed Eslam et al.   GASTROENTEROLOGY

Exogenous Therapeutics of Microrna-29a Attenuates Development of Hepatic Fibrosis in Cholestatic Animal Model through Regulation of Phosphoinositide 3-Kinase p85 Alpha

(2020) Ya-Ling Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement

(2020) Mohammed Eslam et al.   JOURNAL OF HEPATOLOGY

Long term N-acetylcysteine administration rescues liver steatosis via endoplasmic reticulum stress with unfolded protein response in mice

(2020) Ching-Chou Tsai et al.   Lipids in Health and Disease

From NAFLD to MAFLD: when pathophysiology succeeds

(2020) Herbert Tilg et al.   Nature Reviews Gastroenterology & Hepatology

Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis

(2020) Ping An et al.   Nature Communications

The Emerging Role of MicroRNAs in NAFLD: Highlight of MicroRNA-29a in Modulating Oxidative Stress, Inflammation, and Beyond

(2020) Hung-Yu Lin et al.   Cells

Complex Destabilization in the Mitochondrial Chaperonin Hsp60 Leads to Disease

(2020) Alejandro Rodriguez et al.   Frontiers in Molecular Biosciences

miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis

(2020) Ya-Ling Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

History of Nonalcoholic Fatty Liver Disease

(2020) Amedeo Lonardo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice

(2019) Ya-Ling Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cardio-Metabolic Disorders in Non-Alcoholic Fatty Liver Disease

(2019) Hamza El Hadi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure

(2019) Feifei Fan et al.   CELL DEATH AND DIFFERENTIATION

Brain involvement in non-alcoholic fatty liver disease (NAFLD): A systematic review

(2019) Rosa Lombardi et al.   DIGESTIVE AND LIVER DISEASE

ER-residential Nogo-B accelerates NAFLD-associated HCC mediated by metabolic reprogramming of oxLDL lipophagy

(2019) Yuan Tian et al.   Nature Communications

Molecular insights into the role of mitochondria in non-alcoholic fatty liver disease

(2019) Jin Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

MicroRNA-29a Suppresses CD36 to Ameliorate High Fat Diet-Induced Steatohepatitis and Liver Fibrosis in Mice

(2019) Hung-Yu Lin et al.   Cells

Mitochondrial double‐stranded RNA in exosome promotes interleukin‐17 production through toll‐like receptor 3 in alcoholic liver injury

(2019) Jun‐Hee Lee et al.   HEPATOLOGY

Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease

(2018) J.T. Qiao et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

(2018) Ashish Dhir et al.   NATURE

Heat Shock Proteins as Immunomodulants

(2018) Tawanda Zininga et al.   MOLECULES

A spotlight on pathogenesis, interactions and novel therapeutic options in NAFLD

(2018) Ramy Younes et al.   Nature Reviews Gastroenterology & Hepatology

Histone demethylase UTX counteracts glucocorticoid deregulation of osteogenesis by modulating histone-dependent and -independent pathways

(2017) Feng-Sheng Wang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Experimental Milestones in the Discovery of Molecular Chaperones as Polypeptide Unfolding Enzymes

(2016) Andrija Finka et al.   Annual Review of Biochemistry

Chaperonin 60 regulation of SOX9 ubiquitination mitigates the development of knee osteoarthritis

(2016) Jih-Yang Ko et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Nonalcoholic Fatty Liver Disease

(2015) Mary E. Rinella   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MicroRNA-29a protects against acute liver injury in a mouse model of obstructive jaundice via inhibition of the extrinsic apoptosis pathway

(2013) Mao-Meng Tiao et al.   APOPTOSIS

The Clinical Investigation of Disparity of Nonalcoholic Fatty Liver Disease in a Chinese Occupational Population in Taipei, Taiwan

(2013) Jui Wang et al.   Asia-Pacific Journal of Public Health

The Hsp60 folding machinery is crucial for manganese superoxide dismutase folding and function

(2013) R. Magnoni et al.   FREE RADICAL RESEARCH