Cytosolic Quality Control of Mitochondrial Protein Precursors—The Early Stages of the Organelle Biogenesis

Molecular mechanisms and physiological functions of mitophagy

(2021) Mashun Onishi et al.   EMBO JOURNAL

The ER protein Ema19 facilitates the degradation of non-imported mitochondrial precursor proteins

(2021) Janina Laborenz et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial matrix proteases: quality control and beyond

(2021) Karolina Szczepanowska et al.   FEBS Journal

The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress

(2021) Sandra Backes et al.   Cell Reports

A nuclear-based quality control pathway for non-imported mitochondrial proteins

(2021) Viplendra PS Shakya et al.   eLife

Increased levels of mitochondrial import factor Mia40 prevent the aggregation of polyQ proteins in the cytosol

(2021) Anna M Schlagowski et al.   EMBO JOURNAL

Autophagy in metabolic disease and ageing

(2021) Munehiro Kitada et al.   Nature Reviews Endocrinology

Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery

(2021) Wei Qin et al.   Nature Communications

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins

(2021) Urszula Nowicka et al.   eLife

Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway

(2020) Xiaoyan Guo et al.   NATURE

A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol

(2020) Evelyn Fessler et al.   NATURE

Structure of the Bcs1 AAA-ATPase suggests an airlock-like translocation mechanism for folded proteins

(2020) Lukas Kater et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Aggregation of CAT tails blocks their degradation and causes proteotoxicity in S. cerevisiae

(2020) Cole S. Sitron et al.   PLoS One

How the Mitoprotein-Induced Stress Response Safeguards the Cytosol: A Unified View

(2020) Felix Boos et al.   TRENDS IN CELL BIOLOGY

A protein quality control pathway at the mitochondrial outer membrane

(2020) Meredith B Metzger et al.   eLife

Systemic effects of mitochondrial stress

(2020) Raz Bar‐Ziv et al.   EMBO REPORTS

The Yeast Hsp70 Co-chaperone Ydj1 Regulates Functional Distinction of Ssa Hsp70s in the Hsp90 Chaperoning Pathway

(2020) Deepika Gaur et al.   GENETICS

The interaction of the mitochondrial protein importer TOMM34 with HSP70 is regulated by TOMM34 phosphorylation and binding to 14-3-3 adaptors

(2020) Filip Trcka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria as intracellular signaling platforms in health and disease

(2020) Jay X. Tan et al.   JOURNAL OF CELL BIOLOGY

Msp1 cooperates with the proteasome for extraction of arrested mitochondrial import intermediates

(2020) Marion Basch et al.   MOLECULAR BIOLOGY OF THE CELL

Dynamic Regulation of Mitochondrial Import by the Ubiquitin System

(2020) Lilian Phu et al.   MOLECULAR CELL

Detection and Degradation of Stalled Nascent Chains via Ribosome-Associated Quality Control

(2020) Cole S. Sitron et al.   Annual Review of Biochemistry

The C-terminal region of the oxidoreductase MIA40 stabilizes its cytosolic precursor during mitochondrial import

(2020) Lena Maria Murschall et al.   BMC BIOLOGY

Mitochondrial protein biogenesis in the synapse is supported by local translation

(2020) Bozena Kuzniewska et al.   EMBO REPORTS

The coupling of translational control and stress responses

(2020) Ryan Houston et al.   JOURNAL OF BIOCHEMISTRY

Folding the Mitochondrial UPR into the Integrated Stress Response

(2020) Nadine S. Anderson et al.   TRENDS IN CELL BIOLOGY

Mitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane

(2020) Pin-Chao Liao et al.   Cell Reports

Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis

(2020) Tatsuhisa Tsuboi et al.   eLife

Cryo-EM structure of the human mitochondrial translocase TIM22 complex

(2020) Liangbo Qi et al.   CELL RESEARCH

Proteasomal degradation induced by DPP9‐mediated processing competes with mitochondrial protein import

(2020) Yannik Finger et al.   EMBO JOURNAL

Quality control of the mitochondrial proteome

(2020) Jiyao Song et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitin - proteasome system and its crosstalk with mitochondria as therapeutic targets in medicine

(2020) Agata Kodroń et al.   PHARMACOLOGICAL RESEARCH

Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation

(2020) Kim Schneider et al.   Cell Reports

The regulation of mitochondrial homeostasis by the ubiquitin proteasome system

(2020) Cynthia Alsayyah et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial proteins: from biogenesis to functional networks

(2019) Nikolaus Pfanner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Vectorial Import via a Metastable Disulfide-Linked Complex Allows for a Quality Control Step and Import by the Mitochondrial Disulfide Relay

(2019) Markus Habich et al.   Cell Reports

Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme

(2019) Felix Boos et al.   NATURE CELL BIOLOGY

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

(2019) Dongxue Wang et al.   Molecular Systems Biology

Two Alternative Mechanisms Regulate the Onset of Chaperone-mediated Assembly of the Proteasomal ATPases

(2019) Asrafun Nahar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7

(2019) Karthik Mohanraj et al.   EMBO Molecular Medicine

Stop wasting protein—Proteasome inhibition to target diseases linked to mitochondrial import

(2019) Markus Habich et al.   EMBO Molecular Medicine

Mitochondrial stress-dependent regulation of cellular protein synthesis

(2019) Ulrike Topf et al.   JOURNAL OF CELL SCIENCE

Rsp5 and Mdm30 reshape the mitochondrial network in response to age-induced vacuole stress

(2019) Jenna M. Goodrum et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial protein translocation-associated degradation

(2019) Christoph U. Mårtensson et al.   NATURE

Mechanisms and functions of ribosome-associated protein quality control

(2019) Claudio A. P. Joazeiro   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CAT tails drive degradation of stalled polypeptides on and off the ribosome

(2019) Cole S. Sitron et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism for recycling tRNAs on stalled ribosomes

(2019) Matthew C. J. Yip et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis

(2019) Ting Su et al.   NATURE

Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins

(2019) Verena Dederer et al.   eLife

In vitro import experiments with semi-intact cells suggest a role of the Sec61 paralog Ssh1 in mitochondrial biogenesis

(2019) Janina Laborenz et al.   BIOLOGICAL CHEMISTRY

Coupling of import and assembly pathways in mitochondrial protein biogenesis

(2019) Alexander Grevel et al.   BIOLOGICAL CHEMISTRY

Nascent Polypeptide Domain Topology and Elongation Rate Direct the Cotranslational Hierarchy of Hsp70 and TRiC/CCT

(2019) Kevin C. Stein et al.   MOLECULAR CELL

MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure

(2019) Zhihao Wu et al.   MOLECULAR CELL

Mitochondria—Striking a balance between host and endosymbiont

(2019) Richard J. Youle   SCIENCE

Compromised Mitochondrial Protein Import Acts as a Signal for UPRmt

(2019) Stéphane G. Rolland et al.   Cell Reports

Structure of the mitochondrial import gate reveals distinct preprotein paths

(2019) Yuhei Araiso et al.   NATURE

Cryo-EM structure of the mitochondrial protein-import channel TOM complex at near-atomic resolution

(2019) Kyle Tucker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of Factors Involved in Localized Translation Near Mitochondria by Ribosome-Proximity Labeling

(2019) Dikla Vardi-Oknin et al.   Frontiers in Cell and Developmental Biology

A AAA ATPase Cdc48 with a cofactor Ubx2 facilitates ubiquitylation of a mitochondrial fusion-promoting factor Fzo1 for proteasomal degradation

(2019) Sabiqun Nahar et al.   JOURNAL OF BIOCHEMISTRY

Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins

(2018) Lukasz Kowalski et al.   BMC BIOLOGY

Two Cdc48 cofactors Ubp3 and Ubx2 regulate mitochondrial morphology and protein turnover

(2018) Abhijit Chowdhury et al.   JOURNAL OF BIOCHEMISTRY

Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences

(2018) Sandra Backes et al.   JOURNAL OF CELL BIOLOGY

Cytosolic Hsp70 and Hsp40 chaperones enable the biogenesis of mitochondrial β-barrel proteins

(2018) Tobias Jores et al.   JOURNAL OF CELL BIOLOGY

The GET pathway can increase the risk of mitochondrial outer membrane proteins to be mistargeted to the ER

(2018) Daniela G. Vitali et al.   JOURNAL OF CELL SCIENCE

MitoCPR—A surveillance pathway that protects mitochondria in response to protein import stress

(2018) Hilla Weidberg et al.   SCIENCE

Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species

(2018) Ulrike Topf et al.   Nature Communications

An ER surface retrieval pathway safeguards the import of mitochondrial membrane proteins in yeast

(2018) Katja G. Hansen et al.   SCIENCE

Relative timing of mitochondrial endosymbiosis and the “pre-mitochondrial symbioses” hypothesis

(2018) Toni Gabaldón   IUBMB LIFE

Recruitment of Cytosolic J-Proteins by TOM Receptors Promotes Mitochondrial Protein Biogenesis

(2018) Łukasz Opaliński et al.   Cell Reports

Hsp70 - a master regulator in protein degradation

(2017) María Rosario Fernández-Fernández et al.   FEBS LETTERS

mPOS is a novel mitochondrial trigger of cell death - implications for neurodegeneration

(2017) Liam P. Coyne et al.   FEBS LETTERS

Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease

(2017) Désirée Y. van Haaften-Visser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased heme synthesis in yeast induces a metabolic switch from fermentation to respiration even under conditions of glucose repression

(2017) Tiantian Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative Analysis of Mitochondrial N-Termini from Mouse, Human, and Yeast

(2017) Sarah E. Calvo et al.   MOLECULAR & CELLULAR PROTEOMICS

Cytosolic proteostasis through importing of misfolded proteins into mitochondria

(2017) Linhao Ruan et al.   NATURE

Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

(2017) Vincenzo Sorrentino et al.   NATURE

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

The Ribosome as a Platform for mRNA and Nascent Polypeptide Quality Control

(2017) Toshifumi Inada   TRENDS IN BIOCHEMICAL SCIENCES

Control of mitochondrial biogenesis and function by the ubiquitin–proteasome system

(2017) Piotr Bragoszewski et al.   Open Biology

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

(2017) Alexandra M Whiteley et al.   eLife

Dynamic organization of the mitochondrial protein import machinery

(2016) Sebastian P. Straub et al.   BIOLOGICAL CHEMISTRY

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome

(2016) Roland Hjerpe et al.   CELL

Mitochondrial disulfide relay and its substrates: mechanisms in health and disease

(2016) Alican J. Erdogan et al.   CELL AND TISSUE RESEARCH

The life cycle of the 26S proteasome: from birth, through regulation and function and onto its death

(2016) Ido Livneh et al.   CELL RESEARCH

The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR

(2016) Christopher J. Fiorese et al.   CURRENT BIOLOGY

A Eukaryote without a Mitochondrial Organelle

(2016) Anna Karnkowska et al.   CURRENT BIOLOGY

The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication

(2016) Yi Zhang et al.   EMBO JOURNAL

The cytosolic cochaperone Sti1 is relevant for mitochondrial biogenesis and morphology

(2016) Hoda Hoseini et al.   FEBS Journal

Heat Shock Protein 90 kDa (Hsp90) Has a Second Functional Interaction Site with the Mitochondrial Import Receptor Tom70

(2016) Leticia M. Zanphorlin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Doa1 is a MAD adaptor for Cdc48

(2016) Ting Zhang et al.   JOURNAL OF CELL BIOLOGY

Two distinct membrane potential–dependent steps drive mitochondrial matrix protein translocation

(2016) Alexander Benjamin Schendzielorz et al.   JOURNAL OF CELL BIOLOGY

Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system

(2016) Gian-Luca McLelland et al.   JOURNAL OF CELL BIOLOGY

Doa1 targets ubiquitinated substrates for mitochondria-associated degradation

(2016) Xi Wu et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin chain diversity at a glance

(2016) Masato Akutsu et al.   JOURNAL OF CELL SCIENCE

Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors

(2016) Gao Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process

(2016) Giovanna Cenini et al.   MOLECULAR BIOLOGY OF THE CELL

Ribosomal proteins produced in excess are degraded by the ubiquitin–proteasome system

(2016) Min-Kyung Sung et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation

(2016) Eisuke Itakura et al.   MOLECULAR CELL

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A transcriptional signature of Alzheimer’s disease is associated with a metastable subproteome at risk for aggregation

(2016) Prajwal Ciryam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualizing the molecular sociology at the HeLa cell nuclear periphery

(2016) J. Mahamid et al.   SCIENCE

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease

(2016) Roberto Di Maio et al.   Science Translational Medicine

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy

(2016) Thanh N. Nguyen et al.   TRENDS IN CELL BIOLOGY

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An Essential Role for COPI in mRNA Localization to Mitochondria and Mitochondrial Function

(2016) Dmitry Zabezhinsky et al.   Cell Reports

A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins

(2016) Min-Kyung Sung et al.   eLife

Selective sorting and destruction of mitochondrial membrane proteins in aged yeast

(2016) Adam L Hughes et al.   eLife

Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes

(2016) Christopher M. Rose et al.   Cell Systems

PINK1 and Parkin Control Localized Translation of Respiratory Chain Component mRNAs on Mitochondria Outer Membrane

(2015) Stephan Gehrke et al.   Cell Metabolism

Dynamics of co-translational protein targeting

(2015) Margaret M Elvekrog et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Self-clearance mechanism of mitochondrial E3 ligase MARCH5 contributes to mitochondria quality control

(2015) Song-Hee Kim et al.   FEBS Journal

How Hsp70 Molecular Machines Interact with Their Substrates to Mediate Diverse Physiological Functions

(2015) Eugenia M. Clerico et al.   JOURNAL OF MOLECULAR BIOLOGY

Spatially Organized Aggregation of Misfolded Proteins as Cellular Stress Defense Strategy

(2015) Stephanie B.M. Miller et al.   JOURNAL OF MOLECULAR BIOLOGY

The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon

(2015) Karina von der Malsburg et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial and Nuclear Accumulation of the Transcription Factor ATFS-1 Promotes OXPHOS Recovery during the UPRmt

(2015) Amrita M. Nargund et al.   MOLECULAR CELL

A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death

(2015) Xiaowen Wang et al.   NATURE

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

(2015) Lidia Wrobel et al.   NATURE

Retro-translocation of mitochondrial intermembrane space proteins

(2015) Piotr Bragoszewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Supersaturation is a major driving force for protein aggregation in neurodegenerative diseases

(2015) Prajwal Ciryam et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Structure of the native Sec61 protein-conducting channel

(2015) Stefan Pfeffer et al.   Nature Communications

Organelle-Based Aggregation and Retention of Damaged Proteins in Asymmetrically Dividing Cells

(2014) Chuankai Zhou et al.   CELL

Amyloid-β Peptide Induces Mitochondrial Dysfunction by Inhibition of Preprotein Maturation

(2014) Dirk Mossmann et al.   Cell Metabolism

The Protein Import Machinery of Mitochondria—A Regulatory Hub in Metabolism, Stress, and Disease

(2014) Angelika B. Harbauer et al.   Cell Metabolism

Stress-triggered Activation of the Metalloprotease Oma1 Involves Its C-terminal Region and Is Important for Mitochondrial Stress Protection in Yeast

(2014) Iryna Bohovych et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytosolic Quality Control of Mislocalized Proteins Requires RNF126 Recruitment to Bag6

(2014) Monica C. Rodrigo-Brenni et al.   MOLECULAR CELL

Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling

(2014) C. C. Williams et al.   SCIENCE

Cell cycle-dependent regulation of mitochondrial preprotein translocase

(2014) A. B. Harbauer et al.   SCIENCE

Visualizing active membrane protein complexes by electron cryotomography

(2014) Vicki A.M. Gold et al.   Nature Communications

OM14 is a mitochondrial receptor for cytosolic ribosomes that supports co-translational import into mitochondria

(2014) Chen Lesnik et al.   Nature Communications

The Cotranslational Function of Ribosome-Associated Hsp70 in Eukaryotic Protein Homeostasis

(2013) Felix Willmund et al.   CELL

The Ubiquitin-Proteasome System Regulates Mitochondrial Intermembrane Space Proteins

(2013) P. Bragoszewski et al.   MOLECULAR AND CELLULAR BIOLOGY

The Role of Djp1 in Import of the Mitochondrial Protein Mim1 Demonstrates Specificity between a Cochaperone and Its Substrate Protein

(2013) D. Papic et al.   MOLECULAR AND CELLULAR BIOLOGY

SirT3 Regulates the Mitochondrial Unfolded Protein Response

(2013) L. Papa et al.   MOLECULAR AND CELLULAR BIOLOGY

A Cotranslational Ubiquitination Pathway for Quality Control of Misfolded Proteins

(2013) Feng Wang et al.   MOLECULAR CELL

The Ribosome as a Hub for Protein Quality Control

(2013) Sebastian Pechmann et al.   MOLECULAR CELL

Principles of Cotranslational Ubiquitination and Quality Control at the Ribosome

(2013) Stefanie Duttler et al.   MOLECULAR CELL

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

(2013) Shireen A. Sarraf et al.   NATURE

Structural changes in the mitochondrial Tim23 channel are coupled to the proton-motive force

(2013) Ketan Malhotra et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Mitochondrial Odyssey

(2012) Walter Neupert   Annual Review of Biochemistry

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Mechanisms of Sec61/SecY-Mediated Protein Translocation Across Membranes

(2012) Eunyong Park et al.   Annual Review of Biophysics

Mitochondrial protein import: Common principles and physiological networks

(2012) Jan Dudek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

(2012) Vincent Soubannier et al.   CURRENT BIOLOGY

Localization of mRNAs encoding human mitochondrial oxidative phosphorylation proteins

(2012) Shinya Matsumoto et al.   MITOCHONDRION

NAC functions as a modulator of SRP during the early steps of protein targeting to the endoplasmic reticulum

(2012) Ying Zhang et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

(2012) A. M. Nargund et al.   SCIENCE

Roles of Dom34:Hbs1 in Nonstop Protein Clearance from Translocators for Normal Organelle Protein Influx

(2012) Toshiaki Izawa et al.   Cell Reports

Processing of mitochondrial presequences

(2011) Dirk Mossmann et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Tom34: A cytosolic cochaperone of the Hsp90/Hsp70 protein complex involved in mitochondrial protein import

(2011) Pierre Faou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulation of Mitochondrial Protein Import by Cytosolic Kinases

(2011) Oliver Schmidt et al.   CELL

Client-Loading Conformation of the Hsp90 Molecular Chaperone Revealed in the Cryo-EM Structure of the Human Hsp90:Hop Complex

(2011) Daniel R. Southworth et al.   MOLECULAR CELL

Protein targeting and degradation are coupled for elimination of mislocalized proteins

(2011) Tara Hessa et al.   NATURE

Localization of mRNAs coding for mitochondrial proteins in the yeast Saccharomyces cerevisiae

(2011) N. Gadir et al.   RNA

Posttranscriptional control of mitochondrial biogenesis: Spatio-temporal regulation of the protein import process

(2010) Frédéric Devaux et al.   FEBS LETTERS

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PUF proteins: repression, activation and mRNA localization

(2010) Tara Quenault et al.   TRENDS IN CELL BIOLOGY

Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

(2009) F.-Nora Vögtle et al.   CELL

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

(2009) T. Becker et al.   SCIENCE

The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER Membrane

(2008) Maya Schuldiner et al.   CELL

Computational analysis of the human HSPH/HSPA/DNAJ family and cloning of a human HSPH/HSPA/DNAJ expression library

(2008) Jurre Hageman et al.   CELL STRESS & CHAPERONES

Mitochondrial Protein Quality Control by the Proteasome Involves Ubiquitination and the Protease Omi

(2008) Susanne Radke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A molecular pathway of neurodegeneration linking α-synuclein to ApoE and Aβ peptides

(2008) Gilbert Gallardo et al.   NATURE NEUROSCIENCE

Yeast Mitochondrial Biogenesis: A Role for the PUF RNA-Binding Protein Puf3p in mRNA Localization

(2008) Yann Saint-Georges et al.   PLoS One