The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon

Structure and Assembly Pathway of the Ribosome Quality Control Complex

(2015) Sichen Shao et al.   MOLECULAR CELL

Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains

(2015) P. S. Shen et al.   SCIENCE

Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

(2014) Rebecca M. Voorhees et al.   CELL

A “Push and Slide” Mechanism Allows Sequence-Insensitive Translocation of Secretory Proteins by the SecA ATPase

(2014) Benedikt W. Bauer et al.   CELL

Dom34 Rescues Ribosomes in 3′ Untranslated Regions

(2014) Nicholas R. Guydosh et al.   CELL

Protecting the proteome: Eukaryotic cotranslational quality control pathways

(2014) Jens Lykke-Andersen et al.   JOURNAL OF CELL BIOLOGY

Reconstitution of a Minimal Ribosome-Associated Ubiquitination Pathway with Purified Factors

(2014) Sichen Shao et al.   MOLECULAR CELL

Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion

(2014) Marko Gogala et al.   NATURE

Structural basis for translational surveillance by the large ribosomal subunit-associated protein quality control complex

(2014) Dmitry Lyumkis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration

(2014) R. Ishimura et al.   SCIENCE

Structure of the mammalian oligosaccharyl-transferase complex in the native ER protein translocon

(2014) Stefan Pfeffer et al.   Nature Communications

Quality control systems for aberrant mRNAs induced by aberrant translation elongation and termination

(2013) Toshifumi Inada   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Co-translational targeting and translocation of proteins to the endoplasmic reticulum

(2013) Yvonne Nyathi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Listerin-Dependent Nascent Protein Ubiquitination Relies on Ribosome Subunit Dissociation

(2013) Sichen Shao et al.   MOLECULAR CELL

Structure of the SecY channel during initiation of protein translocation

(2013) Eunyong Park et al.   NATURE

Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products

(2013) Q. Defenouillere et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome

(2013) Rati Verma et al.   eLife

A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress

(2012) Onn Brandman et al.   CELL

Dom34:Hbs1 Plays a General Role in Quality-Control Systems by Dissociation of a Stalled Ribosome at the 3′ End of Aberrant mRNA

(2012) Tatsuhisa Tsuboi et al.   MOLECULAR CELL

Translation drives mRNA quality control

(2012) Christopher J Shoemaker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Roles of Dom34:Hbs1 in Nonstop Protein Clearance from Translocators for Normal Organelle Protein Influx

(2012) Toshiaki Izawa et al.   Cell Reports

The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis

(2012) Philipp Kimmig et al.   eLife

Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes

(2011) Vera P Pisareva et al.   EMBO JOURNAL

BiP Modulates the Affinity of Its Co-chaperone ERj1 for Ribosomes

(2010) Julia Benedix et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitylation of an ERAD Substrate Occurs on Multiple Types of Amino Acids

(2010) Yuichiro Shimizu et al.   MOLECULAR CELL

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

(2010) Mario H. Bengtson et al.   NATURE

Dom34:Hbs1 Promotes Subunit Dissociation and Peptidyl-tRNA Drop-Off to Initiate No-Go Decay

(2010) C. J. Shoemaker et al.   SCIENCE

Nascent Peptide-dependent Translation Arrest Leads to Not4p-mediated Protein Degradation by the Proteasome

(2009) Lyudmila N. Dimitrova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

(2009) Julie Hollien et al.   JOURNAL OF CELL BIOLOGY

A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration

(2009) J. Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA