Emerging technologies and their impact on regulatory science

Characterizing the Reproducibility in Using a Liver Microphysiological System for Assaying Drug Toxicity, Metabolism and Accumulation

(2021) Andres Rubiano et al.   CTS-Clinical and Translational Science

Visualizing the spatial localization of ciclesonide and its metabolites in rat lungs after inhalation of 1-μm aerosol of ciclesonide by desorption electrospray ionization-time of flight mass spectrometry imaging

(2021) Eiichi Yamamoto et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Surprising impact of stromal TIL’s on immunotherapy efficacy in a real-world lung cancer study

(2021) S. Hashemi et al.   LUNG CANCER

Metabolomics reveals biomarkers of opioid use disorder

(2021) Reza Ghanbari et al.   Translational Psychiatry

Regulatory landscape of nanotechnology and nanoplastics from a global perspective

(2021) Jacqueline Allan et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Reconstituted Human Organ Models as a Translational Tool for Human Organ Response: Definition, Expectations, Cases, and Strategies for Implementation in Drug Discovery and Development

(2020) Kazuhiro Tetsuka et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

In silico trials: Verification, validation and uncertainty quantification of predictive models used in the regulatory evaluation of biomedical products

(2020) Marco Viceconti et al.   METHODS

iPSC modeling of young-onset Parkinson’s disease reveals a molecular signature of disease and novel therapeutic candidates

(2020) A. H. Laperle et al.   NATURE MEDICINE

Multi-lineage Human iPSC-Derived Platforms for Disease Modeling and Drug Discovery

(2020) Arun Sharma et al.   Cell Stem Cell

Geospatial immune variability illuminates differential evolution of lung adenocarcinoma

(2020) Khalid AbdulJabbar et al.   NATURE MEDICINE

Recent advances in human iPSC-derived models of the blood–brain barrier

(2020) Michael J. Workman et al.   Fluids and Barriers of the CNS

Integrating Multi-Omics Data by Learning Modality Invariant Representations for Improved Prediction of Overall Survival of Cancer

(2020) Li Tong et al.   METHODS

Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936

(2020) Jamie Toombs et al.   Stem Cell Research

Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer

(2020) Adam Pennycuick et al.   Cancer Discovery

Metal‐Specific Biomaterial Accumulation in Human Peri‐Implant Bone and Bone Marrow

(2020) Janosch Schoon et al.   Advanced Science

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

(2020) Heimo Breiteneder et al.   ALLERGY

Whole-brain R1 predicts manganese exposure and biological effects in welders

(2020) David A. Edmondson et al.   ARCHIVES OF TOXICOLOGY

Deep learning based feature-level integration of multi-omics data for breast cancer patients survival analysis

(2020) Li Tong et al.   BMC Medical Informatics and Decision Making

Microengineered systems with iPSC-derived cardiac and hepatic cells to evaluate drug adverse effects

(2020) Keri Dame et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Automatic high-risk fibrosis score prediction using computed tomography imaging

(2020) Elton Rexhepaj et al.   JOURNAL OF HEPATOLOGY

Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC–MS based untargeted metabolomics practitioners

(2020) Anne M. Evans et al.   Metabolomics

Impact of RNA-seq data analysis algorithms on gene expression estimation and downstream prediction

(2020) Li Tong et al.   Scientific Reports

MarkerDB: an online database of molecular biomarkers

(2020) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS)

(2020) Courtney Sakolish et al.   TOXICOLOGY

Untargeted Metabolomics: Biochemical Perturbations in Golestan Cohort Study Opium Users Inform Intervention Strategies

(2020) Yuan-Yuan Li et al.   Frontiers in Nutrition

BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification

(2019) Yannick Djoumbou-Feunang et al.   Journal of Cheminformatics

Follow-Up Liver Stiffness Measurements after Liver Resection Influence Oncologic Outcomes of Hepatitis-B-Associated Hepatocellular Carcinoma with Liver Cirrhosis

(2019) Jung Lee et al.   Cancers

Risks and Benefits of Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Cancer: A Systematic Review and Meta-Analysis

(2019) Emma J.M. Grigor et al.   TRANSFUSION MEDICINE REVIEWS

Hepatocyte Concentrations of Imaging Compounds Associated with Transporter Inhibition: Evidence in Perfused Rat Livers

(2019) Pierre Bonnaventure et al.   DRUG METABOLISM AND DISPOSITION

Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study

(2019) Andrea L. Jorgensen et al.   BMC Medicine

Liver Microphysiological Systems for Predicting and Evaluating Drug Effects

(2019) Alexandre J.S. Ribeiro et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The present and future of deep learning in radiology

(2019) Luca Saba et al.   EUROPEAN JOURNAL OF RADIOLOGY

An Integrated Analysis of Metabolites, Peptides and Inflammation Biomarkers for Assessment of Pre-analytical Variability of Human Plasma

(2019) Zhijun Cao et al.   JOURNAL OF PROTEOME RESEARCH

Gadolinium Retention in the Brain: An MRI Relaxometry Study of Linear and Macrocyclic Gadolinium-Based Contrast Agents in Multiple Sclerosis

(2019) Y. Forslin et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications

(2019) Gad D. Vatine et al.   Cell Stem Cell

Organoids-on-a-chip

(2019) Sunghee Estelle Park et al.   SCIENCE

Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

(2019) Mark R. Viant et al.   Nature Communications

jmzTab-M: A Reference Parser, Writer, and Validator for the Proteomics Standards Initiative mzTab 2.0 Metabolomics Standard

(2019) Nils Hoffmann et al.   ANALYTICAL CHEMISTRY

Reversibility of Neuroimaging Markers Influenced by Lifetime Occupational Manganese Exposure

(2019) David A Edmondson et al.   TOXICOLOGICAL SCIENCES

Tetrafluoroethylene-Propylene Elastomer for Fabrication of Microfluidic Organs-on-Chips Resistant to Drug Absorption

(2019) Emi Sano et al.   Micromachines

Preclinical safety evaluation of chimeric antigen receptor-modified T cells against CD19 in NSG mice

(2019) Hairuo Wen et al.   Annals of Translational Medicine

A review of privacy-preserving techniques for deep learning

(2019) Amine Boulemtafes et al.   NEUROCOMPUTING

Explainable Artificial Intelligence (XAI): Concepts, taxonomies, opportunities and challenges toward responsible AI

(2019) Alejandro Barredo Arrieta et al.   Information Fusion

Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF-06372865

(2018) Sarah A Nickolls et al.   BRITISH JOURNAL OF PHARMACOLOGY

Advanced imaging modalities to detect cardiotoxicity

(2018) Magid Awadalla et al.   CURRENT PROBLEMS IN CANCER

Organ/body-on-a-chip based on microfluidic technology for drug discovery

(2018) Hiroshi Kimura et al.   Drug Metabolism and Pharmacokinetics

Organs-on-a-chip: Current applications and consideration points for in vitro ADME-Tox studies

(2018) Seiichi Ishida   Drug Metabolism and Pharmacokinetics

Glyphosate has limited short-term effects on commensal bacterial community composition in the gut environment due to sufficient aromatic amino acid levels

(2018) Lene Nørby Nielsen et al.   ENVIRONMENTAL POLLUTION

A multi-throughput multi-organ-on-a-chip system on a plate formatted pneumatic pressure-driven medium circulation platform

(2018) T. Satoh et al.   LAB ON A CHIP

Comparison of quantitative T 2 and ADC mapping in the assessment of 3-nitropropionic acid-induced neurotoxicity in rats

(2018) Serguei Liachenko et al.   NEUROTOXICOLOGY

Discovery of Negative-Sense RNA Viruses in Trees Infected with Apple Rubbery Wood Disease by Next-Generation Sequencing

(2018) Michael E. Rott et al.   PLANT DISEASE

A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function

(2018) Anastassia Karageorgis et al.   PLoS One

Diet and microbiota linked in health and disease

(2018) T. Requena et al.   Food & Function

OUP accepted manuscript

(2018)   Advances in Nutrition

Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development

(2018) Samuel Sances et al.   Stem Cell Reports

Evaluating automated approaches to anaphylaxis case classification using unstructured data from the FDA Sentinel System

(2018) Robert Ball et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Fully automated and integrated multiplex detection of high consequence livestock viral genomes on a microfluidic platform

(2018) Oliver Lung et al.   Transboundary and Emerging Diseases

Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip

(2018) Courtney Sakolish et al.   Scientific Reports

Functional Profiling of Chondrogenically Induced Multipotent Stromal Cell Aggregates Reveals Transcriptomic and Emergent Morphological Phenotypes Predictive of Differentiation Capacity

(2018) Johnny Lam et al.   Stem Cells Translational Medicine

Gadolinium Deposition in Brain: Current Scientific Evidence and Future Perspectives

(2018) Bang J. Guo et al.   Frontiers in Molecular Neuroscience

A Structured Survey on Adverse Events Occurring Within 24 Hours After Intravenous Exposure to Gadodiamide or Gadoterate Meglumine

(2018) Marco Parillo et al.   INVESTIGATIVE RADIOLOGY

Genomically Informed Strain-Specific Recovery of Shiga Toxin–Producing Escherichia coli during Foodborne Illness Outbreak Investigations

(2018) BURTON W. BLAIS et al.   JOURNAL OF FOOD PROTECTION

The FDA Sentinel Initiative — An Evolving National Resource

(2018) Richard Platt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Biomarkers for the detection of apparent and subclinical cancer therapy-related cardiotoxicity

(2018) Lars Michel et al.   Journal of Thoracic Disease

Drug-Induced Interstitial Lung Disease: A Systematic Review

(2018) Sarah Skeoch et al.   Journal of Clinical Medicine

Organs-on-chips: Progress, challenges, and future directions

(2017) Lucie A Low et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective

(2017) Lorna Ewart et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Baseline Practices for the Application of Genomic Data Supporting Regulatory Food Safety

(2017) Dominic Lambert et al.   JOURNAL OF AOAC INTERNATIONAL

Theranostics Using Antibodies and Antibody-Related Therapeutics

(2017) Kirsten L. Moek et al.   JOURNAL OF NUCLEAR MEDICINE

Bone marrow-on-a-chip: Long-term culture of human haematopoietic stem cells in a three-dimensional microfluidic environment

(2017) Stefan Sieber et al.   Journal of Tissue Engineering and Regenerative Medicine

Reference standards for next-generation sequencing

(2017) Simon A. Hardwick et al.   NATURE REVIEWS GENETICS

Tracking the Evolution of Non–Small-Cell Lung Cancer

(2017) Mariam Jamal-Hanjani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

(2017) Sattva S. Neelapu et al.   NEW ENGLAND JOURNAL OF MEDICINE

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

HMDB 4.0: the human metabolome database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

What evidence do we need for biomarker qualification?

(2017) Chris Leptak et al.   Science Translational Medicine

Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits

(2017) Ryan G. Lim et al.   Cell Reports

Translating New Science Into the Drug Review Process

(2017) Rodney Rouse et al.   Therapeutic Innovation & Regulatory Science

Workshop Report: Crystal City VI—Bioanalytical Method Validation for Biomarkers

(2016) Mark E. Arnold et al.   AAPS Journal

Potent Anti-leukemia Activities of Chimeric Antigen Receptor–Modified T Cells against CD19 in Chinese Patients with Relapsed/Refractory Acute Lymphocytic Leukemia

(2016) Yongxian Hu et al.   CLINICAL CANCER RESEARCH

The FDA's sentinel initiative-A comprehensive approach to medical product surveillance

(2016) R Ball et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The mouse gut microbiome revisited: From complex diversity to model ecosystems

(2016) Thomas Clavel et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Two Phase 2 Multiple Ascending–Dose Studies of Vanutide Cridificar (ACC-001) and QS-21 Adjuvant in Mild-to-Moderate Alzheimer’s Disease

(2016) Florence Pasquier et al.   JOURNAL OF ALZHEIMERS DISEASE

Quantification and reproducibility assessment of the regional brain T 2 relaxation in naïve rats at 7T

(2016) Serguei Liachenko et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Development of a microphysiological model of human kidney proximal tubule function

(2016) Elijah J. Weber et al.   KIDNEY INTERNATIONAL

Metabolomics enables precision medicine: “A White Paper, Community Perspective”

(2016) Richard D. Beger et al.   Metabolomics

Representing genetic variation with synthetic DNA standards

(2016) Ira W Deveson et al.   NATURE METHODS

Imaging biomarker roadmap for cancer studies

(2016) James P. B. O'Connor et al.   Nature Reviews Clinical Oncology

Longitudinal diffusion tensor imaging of the rat brain after hexachlorophene exposure

(2016) Jaivijay Ramu et al.   NEUROTOXICOLOGY

Long term use of analgesics and risk of osteoarthritis progressions and knee replacement: propensity score matched cohort analysis of data from the Osteoarthritis Initiative

(2016) N. Hafezi-Nejad et al.   OSTEOARTHRITIS AND CARTILAGE

Microbes Drive Evolution of Animals and Plants: the Hologenome Concept

(2016) Eugene Rosenberg et al.   mBio

First-In-Human safety and long-term exposure data for AAB-003 (PF-05236812) and biomarkers after intravenous infusions of escalating doses in patients with mild to moderate Alzheimer’s disease

(2016) Marielle Delnomdedieu et al.   Alzheimers Research & Therapy

Human Engineered Heart Tissue: Analysis of Contractile Force

(2016) Ingra Mannhardt et al.   Stem Cell Reports

Extensive sequencing of seven human genomes to characterize benchmark reference materials

(2016) Justin M. Zook et al.   Scientific Data

Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes

(2016) Kevin R. Theis et al.   mSystems

Facilitating the commercialization and use of organ platforms generated by the microphysiological systems (Tissue Chip) program through public–private partnerships

(2016) Christine A. Livingston et al.   Computational and Structural Biotechnology Journal

Translational biomarkers of acetaminophen-induced acute liver injury

(2015) Richard D. Beger et al.   ARCHIVES OF TOXICOLOGY

A human liver microphysiology platform for investigating physiology, drug safety, and disease models

(2015) Lawrence A Vernetti et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity

(2015) Munir Pirmohamed et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism

(2015) Marcus J. Miller et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Development of human colonic microbiota in the computer-controlled dynamic SIMulator of the GastroIntestinal tract SIMGI

(2015) Elvira Barroso et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Erratum to: COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

(2015) Reza M. Salek et al.   Metabolomics

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

Imaging atlas for eligibility and on-study safety of potential knee adverse events in anti-NGF studies (Part 1)

(2015) F.W. Roemer et al.   OSTEOARTHRITIS AND CARTILAGE

Imaging atlas for eligibility and on-study safety of potential hip adverse events in anti-NGF studies (Part 2)

(2015) F.W. Roemer et al.   OSTEOARTHRITIS AND CARTILAGE

Quantitative Assessment of MRIT2Response to Kainic Acid Neurotoxicity in Ratsin vivo

(2015) Serguei Liachenko et al.   TOXICOLOGICAL SCIENCES

Mesothelin-Targeted CARs: Driving T Cells to Solid Tumors

(2015) A. Morello et al.   Cancer Discovery

μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips

(2015) Peter Loskill et al.   PLoS One

The Influence of Glyphosate on the Microbiota and Production of Botulinum Neurotoxin During Ruminal Fermentation

(2014) Wagis Ackermann et al.   CURRENT MICROBIOLOGY

Expert Consensus for Multimodality Imaging Evaluation of Adult Patients during and after Cancer Therapy: A Report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging

(2014) Juan Carlos Plana et al.   JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

(2014) Jotham Suez et al.   NATURE

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

(2014)   NATURE BIOTECHNOLOGY

Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

(2014) David Cook et al.   NATURE REVIEWS DRUG DISCOVERY

T3DB: the toxic exposome database

(2014) David Wishart et al.   NUCLEIC ACIDS RESEARCH

The use of MRI to assist the section selections for classical pathology assessment of neurotoxicity

(2014) Joseph Hanig et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Reliable Generation of Induced Pluripotent Stem Cells From Human Lymphoblastoid Cell Lines

(2014) Robert Barrett et al.   Stem Cells Translational Medicine

Medication-induced osteoporosis: screening and treatment strategies

(2014) Keshav Panday et al.   Therapeutic Advances in Musculoskeletal Disease

An MRI Rating Scale for Amyloid-Related Imaging Abnormalities with Edema or Effusion

(2013) F. Barkhof et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Engineering of functional, perfusable 3D microvascular networks on a chip

(2013) Sudong Kim et al.   LAB ON A CHIP

Six red flags for suspect work

(2013) C. Glenn Begley   NATURE

A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing

(2013) Stephen E. Kimmel et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized Trial of Genotype-Guided Dosing of Warfarin

(2013) Munir Pirmohamed et al.   NEW ENGLAND JOURNAL OF MEDICINE

Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibition

(2013) Jose L. Ulloa et al.   NMR IN BIOMEDICINE

High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-weighted MR Images: Relationship with Increasing Cumulative Dose of a Gadolinium-based Contrast Material

(2013) Tomonori Kanda et al.   RADIOLOGY

Dissemination of metabolomics results: role of MetaboLights and COSMOS

(2013) Reza M Salek et al.   GigaScience

The Effect of Glyphosate on Potential Pathogens and Beneficial Members of Poultry Microbiota In Vitro

(2012) Awad A. Shehata et al.   CURRENT MICROBIOLOGY

Role of Ultrasonography in the Differential Diagnosis of Thyrotoxicosis: A Noninvasive, Cost-Effective, and Widely Available but Underutilized Diagnostic Tool

(2012) Ali Alzahrani et al.   Endocrine Practice

Fibronectin and stem cell differentiation - lessons from chondrogenesis

(2012) P. Singh et al.   JOURNAL OF CELL SCIENCE

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival

(2011) Paul Morgan et al.   DRUG DISCOVERY TODAY

Recommended Neuroanatomical Sampling Practices for Comprehensive Brain Evaluation in Nonclinical Safety Studies

(2011) Robert C. Switzer et al.   TOXICOLOGIC PATHOLOGY

Characterization of human B cells in umbilical cord blood-transplanted NOD/SCID mice

(2011) Xuefu Wang et al.   TRANSPLANT IMMUNOLOGY

Dopamine D2 Occupancy as a Biomarker for Antipsychotics: Quantifying the Relationship with Efficacy and Extrapyramidal Symptoms

(2010) Rik de Greef et al.   AAPS Journal

Global genome analysis of the shikimic acid pathway reveals greater gene loss in host-associated than in free-living bacteria

(2010) Jurica Zucko et al.   BMC GENOMICS

Antipsychotic Occupancy of Dopamine Receptors in Schizophrenia

(2010) Magdalena Nord et al.   CNS Neuroscience & Therapeutics

Trastuzumab-Induced Cardiotoxicity: Clinical and Prognostic Implications of Troponin I Evaluation

(2010) Daniela Cardinale et al.   JOURNAL OF CLINICAL ONCOLOGY

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Production of aromatic compounds in bacteria

(2009) Guillermo Gosset   CURRENT OPINION IN BIOTECHNOLOGY

The Microbleed Anatomical Rating Scale (MARS): Reliability of a tool to map brain microbleeds

(2009) S. M. Gregoire et al.   NEUROLOGY

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

(2009) S. Salloway et al.   NEUROLOGY

Adverse Drug Reactions in Hospital In-Patients: A Prospective Analysis of 3695 Patient-Episodes

(2009) Emma C. Davies et al.   PLoS One

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

(2009) T. A. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity

(2009) Richard D. Beger et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

The usefulness of 99mTc-sestaMIBI thyroid scan in the differential diagnosis and management of amiodarone-induced thyrotoxicosis

(2008) M Piga et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Molecular imaging in drug development

(2008) Jürgen K. Willmann et al.   NATURE REVIEWS DRUG DISCOVERY

The Design and Fabrication of Three-Chamber Microscale Cell Culture Analog Devices with Integrated Dissolved Oxygen Sensors

(2004) Aaron Sin et al.   BIOTECHNOLOGY PROGRESS