Bone marrow-on-a-chip: Long-term culture of human haematopoietic stem cells in a three-dimensional microfluidic environment

Engineering Stem Cell Organoids

(2016) Xiaolei Yin et al.   Cell Stem Cell

Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science

(2015) Ji Sun Choi et al.   Biotechnology Journal

Organ-On-A-Chip: Development and Clinical Prospects Toward Toxicity Assessment with an Emphasis on Bone Marrow

(2015) Jeehye Kim et al.   DRUG SAFETY

Chip-based human liver–intestine and liver–skin co-cultures – A first step toward systemic repeated dose substance testing in vitro

(2015) Ilka Maschmeyer et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

(2015) Ilka Maschmeyer et al.   LAB ON A CHIP

Microfluidic vascularized bone tissue model with hydroxyapatite-incorporated extracellular matrix

(2015) Norhana Jusoh et al.   LAB ON A CHIP

Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science

(2015) Ji Sun Choi et al.   Biotechnology Journal

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Bone marrow–on–a–chip replicates hematopoietic niche physiology in vitro

(2014) Yu-suke Torisawa et al.   NATURE METHODS

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

SLAM Family Markers Resolve Functionally Distinct Subpopulations of Hematopoietic Stem Cells and Multipotent Progenitors

(2013) Hideyuki Oguro et al.   Cell Stem Cell

Integrating biological vasculature into a multi-organ-chip microsystem

(2013) Katharina Schimek et al.   LAB ON A CHIP

Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion

(2013) Beren Ataç et al.   LAB ON A CHIP

A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture

(2013) Ilka Wagner et al.   LAB ON A CHIP

Arteriolar niches maintain haematopoietic stem cell quiescence

(2013) Yuya Kunisaki et al.   NATURE

Hematopoietic stem cell expansion: challenges and opportunities

(2012) Marta A. Walasek et al.   Annals of the New York Academy of Sciences

Cord blood-hematopoietic stem cell expansion in 3D fibrin scaffolds with stromal support

(2012) Mónica S. Ventura Ferreira et al.   BIOMATERIALS

Molecular signature and in vivo behavior of bone marrow endosteal and subendosteal stromal cell populations and their relevance to hematopoiesis

(2012) Alex Balduino et al.   EXPERIMENTAL CELL RESEARCH

3D co-culture of hematopoietic stem and progenitor cells and mesenchymal stem cells in collagen scaffolds as a model of the hematopoietic niche

(2011) Isabelle Leisten et al.   BIOMATERIALS

Hematopoietic Stem Cells: Transcriptional Regulation, Ex Vivo Expansion and Clinical Application

(2011) R. Aggarwal et al.   CURRENT MOLECULAR MEDICINE

Mimicking the functional hematopoietic stem cell niche in vitro: recapitulation of marrow physiology by hydrogel-based three-dimensional cultures of mesenchymal stromal cells

(2011) M. B. Sharma et al.   HAEMATOLOGICA

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

(2011) F. Notta et al.   SCIENCE

Micromarrows—Three-Dimensional Coculture of Hematopoietic Stem Cells and Mesenchymal Stromal Cells

(2011) Matthew M. Cook et al.   TISSUE ENGINEERING PART C-METHODS

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Control of hematopoietic stem cells by the bone marrow stromal niche: the role of reticular cells

(2011) Takashi Nagasawa et al.   TRENDS IN IMMUNOLOGY

The Haematopoietic Stem Cell Niche: New Insights into the Mechanisms Regulating Haematopoietic Stem Cell Behaviour

(2011) Andrew J. Lilly et al.   Stem Cells International

Toward modeling the bone marrow niche using scaffold-based 3D culture systems

(2010) Nunzia Di Maggio et al.   BIOMATERIALS

Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation

(2010) Song Chou et al.   Cell Stem Cell

Maintenance and expansion of hematopoietic stem/progenitor cells in biomimetic osteoblast niche

(2010) Jing Tan et al.   CYTOTECHNOLOGY

Design and prototyping of a chip-based multi-micro-organoid culture system for substance testing, predictive to human (substance) exposure

(2010) Frank Sonntag et al.   JOURNAL OF BIOTECHNOLOGY

The endosteal ‘osteoblastic’ niche and its role in hematopoietic stem cell homing and mobilization

(2010) J-P Lévesque et al.   LEUKEMIA

The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering

(2009) Ciara M. Murphy et al.   BIOMATERIALS