Chaperoning histones at the DNA repair dance

Strand-specific ChIP-seq at DNA breaks distinguishes ssDNA versus dsDNA binding and refutes single-stranded nucleosomes

(2021) Martina Peritore et al.   MOLECULAR CELL

Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication

(2021) Vinay Tripuraneni et al.   GENOME RESEARCH

Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance

(2021) Anna Fortuny et al.   Nature Communications

Dissecting regulatory pathways for transcription recovery following DNA damage reveals a non-canonical function of the histone chaperone HIRA

(2021) Déborah Bouvier et al.   Nature Communications

The replisome guides nucleosome assembly during DNA replication

(2020) Wenshuo Zhang et al.   Cell and Bioscience

Control of the chromatin response to DNA damage: Histone proteins pull the strings

(2020) Juliette Ferrand et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement

(2020) Anaïs Cheblal et al.   MOLECULAR CELL

A Snapshot on the Cis Chromatin Response to DNA Double-Strand Breaks

(2019) Thomas Clouaire et al.   TRENDS IN GENETICS

Plugged into the Ku-DNA hub: The NHEJ network

(2019) Philippe Frit et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Chromatin Modifiers Alter Recombination Between Divergent DNA Sequences

(2019) Ujani Chakraborty et al.   GENETICS

Nej1 Interacts with Mre11 to Regulate Tethering and Dna2 Binding at DNA Double-Strand Breaks

(2019) Aditya Mojumdar et al.   Cell Reports

Histone deposition promotes recombination-dependent replication at arrested forks

(2019) Julien Hardy et al.   PLoS Genetics

Chromatin remodeling and mismatch repair: Access and excision

(2019) Eva M. Goellner   DNA REPAIR

Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair

(2018) Zhiming Li et al.   CELL RESEARCH

Nucleosomes around a mismatched base pair are excluded via an Msh2-dependent reaction with the aid of SNF2 family ATPase Smarcad1

(2018) Riki Terui et al.   GENES & DEVELOPMENT

ATRX Promotes DNA Repair Synthesis and Sister Chromatid Exchange during Homologous Recombination

(2018) Szilvia Juhász et al.   MOLECULAR CELL

The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells

(2018) Ting-Hsiang Huang et al.   MOLECULAR CELL

DNA repair factor APLF acts as a H2A-H2B histone chaperone through binding its DNA interaction surface

(2018) Ivan Corbeski et al.   NUCLEIC ACIDS RESEARCH

Somatic and Germline Mutation Periodicity Follow the Orientation of the DNA Minor Groove around Nucleosomes

(2018) Oriol Pich et al.   CELL

The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage

(2018) Sandra Piquet et al.   MOLECULAR CELL

Bre1-dependent H2B ubiquitination promotes homologous recombination by stimulating histone eviction at DNA breaks

(2018) Sihao Zheng et al.   NUCLEIC ACIDS RESEARCH

Chromatin and nucleosome dynamics in DNA damage and repair

(2017) Michael H. Hauer et al.   GENES & DEVELOPMENT

Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity

(2017) Peng Mao et al.   GENOME RESEARCH

Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes

(2017) Cedric R. Clapier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates

(2017) Michael H Hauer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA repair goes hip-hop: SMARCA and CHD chromatin remodellers join the break dance

(2017) Magdalena B. Rother et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Delineation of the role of chromatin assembly and the Rtt101Mms1 E3 ubiquitin ligase in DNA damage checkpoint recovery in budding yeast

(2017) Li-Ting Diao et al.   PLoS One

A global view of meiotic double-strand break end resection

(2017) Eleni P. Mimitou et al.   SCIENCE

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates

(2017) Michael H Hauer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Consider the workhorse: Nonhomologous end-joining in budding yeast

(2016) Charlene H. Emerson et al.   Biochemistry and Cell Biology

Mechanism and regulation of DNA end resection in eukaryotes

(2016) Lorraine S. Symington   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Re-establishment of nucleosome occupancy during double-strand break repair in budding yeast

(2016) Michael Tsabar et al.   DNA REPAIR

Site-specific Acetylation of Histone H3 Decreases Polymerase β Activity on Nucleosome Core Particlesin Vitro

(2016) Yesenia Rodriguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Mismatch Repair Interacts with CAF-1- and ASF1A-H3-H4-dependent Histone (H3-H4)2Tetramer Deposition

(2016) Elena Rodriges Blanko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Major Replicative Histone Chaperone CAF-1 Suppresses the Activity of the DNA Mismatch Repair System in the Cytotoxic Response to a DNA-methylating Agent

(2016) Lyudmila Y. Kadyrova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex

(2016) Michal Hammel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining

(2016) Martijn S. Luijsterburg et al.   MOLECULAR CELL

Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesis

(2016) Sheera Adar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Histone Chaperone FACT Contributes to DNA Replication-Coupled Nucleosome Assembly

(2016) Jiayi Yang et al.   Cell Reports

FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC

(2016) John Lalith Charles Richard et al.   PLoS Genetics

Eukaryotic Mismatch Repair in Relation to DNA Replication

(2015) Thomas A. Kunkel et al.   Annual Review of Genetics

Chromatin dynamics after DNA damage: The legacy of the access–repair–restore model

(2015) Sophie E. Polo et al.   DNA REPAIR

Accessing DNA damage in chromatin: Preparing the chromatin landscape for base excision repair

(2015) Yesenia Rodriguez et al.   DNA REPAIR

Two distinct modes for propagation of histone PTMs across the cell cycle

(2015) Constance Alabert et al.   GENES & DEVELOPMENT

DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous Recombination

(2015) Petr Cejka   JOURNAL OF BIOLOGICAL CHEMISTRY

High-Resolution Chromatin Dynamics during a Yeast Stress Response

(2015) Assaf Weiner et al.   MOLECULAR CELL

Cell-of-origin chromatin organization shapes the mutational landscape of cancer

(2015) Paz Polak et al.   NATURE

Histone chaperone Anp32e removes H2A.Z from DNA double-strand breaks and promotes nucleosome reorganization and DNA repair

(2015) Ozge Gursoy-Yuzugullu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin remodelling complex RSC promotes base excision repair in chromatin of Saccharomyces cerevisiae

(2014) Wioletta Czaja et al.   DNA REPAIR

Mechanisms and Regulation of Mitotic Recombination in Saccharomyces cerevisiae

(2014) L. S. Symington et al.   GENETICS

Histone H3 Lysine 14 (H3K14) Acetylation Facilitates DNA Repair in a Positioned Nucleosome by Stabilizing the Binding of the Chromatin Remodeler RSC (Remodels Structure of Chromatin)

(2014) Ming-Rui Duan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding nucleotide excision repair and its roles in cancer and ageing

(2014) Jurgen A. Marteijn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human ISWI complexes are targeted by SMARCA5 ATPase and SLIDE domains to help resolve lesion-stalled transcription

(2014) Özge Z. Aydin et al.   NUCLEIC ACIDS RESEARCH

Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair

(2014) A. Mehta et al.   Cold Spring Harbor Perspectives in Biology

The Chromatin Assembly Factor 1 Promotes Rad51-Dependent Template Switches at Replication Forks by Counteracting D-Loop Disassembly by the RecQ-Type Helicase Rqh1

(2014) Violena Pietrobon et al.   PLOS BIOLOGY

Transcription Recovery after DNA Damage Requires Chromatin Priming by the H3.3 Histone Chaperone HIRA

(2013) Salomé Adam et al.   CELL

The Structural Location of DNA Lesions in Nucleosome Core Particles Determines Accessibility by Base Excision Repair Enzymes

(2013) Yesenia Rodriguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced Chromatin Dynamics by FACT Promotes Transcriptional Restart after UV-Induced DNA Damage

(2013) Christoffel Dinant et al.   MOLECULAR CELL

Nucleosome dynamics regulates DNA processing

(2013) Nicholas L Adkins et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair

(2013) M. Goldstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Base Excision Repair

(2013) H. E. Krokan et al.   Cold Spring Harbor Perspectives in Biology

Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase

(2012) Li Lan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The chromatin remodeler p400 ATPase facilitates Rad51-mediated repair of DNA double-strand breaks

(2012) Céline Courilleau et al.   JOURNAL OF CELL BIOLOGY

The Saccharomyces cerevisiae Chromatin Remodeler Fun30 Regulates DNA End Resection and Checkpoint Deactivation

(2012) V. V. Eapen et al.   MOLECULAR AND CELLULAR BIOLOGY

Prime, Repair, Restore: The Active Role of Chromatin in the DNA Damage Response

(2012) Gaston Soria et al.   MOLECULAR CELL

Histone H2A.Z Controls a Critical Chromatin Remodeling Step Required for DNA Double-Strand Break Repair

(2012) Ye Xu et al.   MOLECULAR CELL

The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection

(2012) Thomas Costelloe et al.   NATURE

The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends

(2012) Xuefeng Chen et al.   NATURE

Nucleolin Participates in DNA Double-Strand Break-Induced Damage Response through MDC1-Dependent Pathway

(2012) Junya Kobayashi et al.   PLoS One

Interplay between mismatch repair and chromatin assembly

(2012) B. Schopf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the mammalian SWI/SNF chromatin remodeling complex in the cellular response to UV damage

(2011) Feng Gong et al.   CELL CYCLE

The chromatin remodeling factor BRG1 stimulates nucleotide excision repair by facilitating recruitment of XPC to sites of DNA damage

(2011) Ling Zhang et al.   CELL CYCLE

Nucleotide excision repair in chromatin: Damage removal at the drop of a HAT

(2011) Simon H. Reed   DNA REPAIR

A review of recent experiments on step-to-step “hand-off” of the DNA intermediates in mammalian base excision repair pathways

(2011) R. Prasad et al.   MOLECULAR BIOLOGY

DNA Repair Factor APLF Is a Histone Chaperone

(2011) Pawan Vinod Mehrotra et al.   MOLECULAR CELL

Dynamics of Histone H3 Deposition In Vivo Reveal a Nucleosome Gap-Filling Mechanism for H3.3 to Maintain Chromatin Integrity

(2011) Dominique Ray-Gallet et al.   MOLECULAR CELL

ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation

(2011) Aruna Battu et al.   NUCLEIC ACIDS RESEARCH

Base excision repair of 8-oxoG in dinucleosomes

(2011) Hervé Menoni et al.   NUCLEIC ACIDS RESEARCH

CAF-I-dependent control of degradation of the discontinuous strands during mismatch repair

(2011) L. Y. Kadyrova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of Damaged DNA Bases by DNA Glycosylase Enzymes

(2010) Joshua I. Friedman et al.   BIOCHEMISTRY

Chaperoning Histones during DNA Replication and Repair

(2010) Monica Ransom et al.   CELL

High-resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome

(2010) Jason S Iacovoni et al.   EMBO JOURNAL

Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice

(2010) Jason Gorman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rotational dynamics of DNA on the nucleosome surface markedly impact accessibility to a DNA repair enzyme

(2010) J. M. Hinz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway

(2010) Y. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

(2009) Kent S. Gates   CHEMICAL RESEARCH IN TOXICOLOGY

Evidence That Nucleosomes Inhibit Mismatch Repair in Eukaryotic Cells

(2009) Feng Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Nucleotide Excision Repair by Mammalian SWI/SNF Chromatin-remodeling Complex

(2009) Qun Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleotide excision repair–induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

(2009) Jurgen A. Marteijn et al.   JOURNAL OF CELL BIOLOGY

Human SNF5/INI1, a Component of the Human SWI/SNF Chromatin Remodeling Complex, Promotes Nucleotide Excision Repair by Influencing ATM Recruitment and Downstream H2AX Phosphorylation

(2009) A. Ray et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin assembly factors Asf1 and CAF-1 have overlapping roles in deactivating the DNA damage checkpoint when DNA repair is complete

(2009) J.-A. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cullin 4B-Based UV-Damaged DNA-Binding Protein Ligase Binds to UV-Damaged Chromatin and Ubiquitinates Histone H2A

(2008) J. Guerrero-Santoro et al.   CANCER RESEARCH

Acetylation of Histone H3 Lysine 56 Regulates Replication-Coupled Nucleosome Assembly

(2008) Qing Li et al.   CELL

Acetylated Lysine 56 on Histone H3 Drives Chromatin Assembly after Repair and Signals for the Completion of Repair

(2008) Chin-Chuan Chen et al.   CELL

Platinum Resistance: The Role of DNA Repair Pathways

(2008) L. P. Martin et al.   CLINICAL CANCER RESEARCH

Base Excision Repair and its Role in Maintaining Genome Stability

(2008) Joke Baute et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites

(2008) Qianzheng Zhu et al.   DNA REPAIR

Transcription-coupled DNA repair: two decades of progress and surprises

(2008) Philip C. Hanawalt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY