Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes

Interdomain Communication of the Chd1 Chromatin Remodeler across the DNA Gyres of the Nucleosome

(2017) Ilana M. Nodelman et al.   MOLECULAR CELL

Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure

(2017) Xiaoyu Liu et al.   NATURE

Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler

(2017) Kalyan K. Sinha et al.   SCIENCE

Concerted regulation of ISWI by an autoinhibitory domain and the H4 N-terminal tail

(2017) Johanna Ludwigsen et al.   eLife

EP400 Deposits H3.3 into Promoters and Enhancers during Gene Activation

(2016) Suman K. Pradhan et al.   MOLECULAR CELL

Regulation of DNA Translocation Efficiency within the Chromatin Remodeler RSC/Sth1 Potentiates Nucleosome Sliding and Ejection

(2016) Cedric R. Clapier et al.   MOLECULAR CELL

Structure and regulation of the chromatin remodeller ISWI

(2016) Lijuan Yan et al.   NATURE

Structure of chromatin remodeler Swi2/Snf2 in the resting state

(2016) Xian Xia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synergy and antagonism in regulation of recombinant human INO80 chromatin remodeling complex

(2016) Oliver Willhoft et al.   NUCLEIC ACIDS RESEARCH

The ISW1 and CHD1 ATP-dependent chromatin remodelers compete to set nucleosome spacingin vivo

(2016) Josefina Ocampo et al.   NUCLEIC ACIDS RESEARCH

The Chd1 chromatin remodeler can sense both entry and exit sides of the nucleosome

(2016) Ilana M. Nodelman et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of a nuclear actin ternary complex

(2016) Tingting Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of chromatin remodeler Swi2/Snf2 in the resting state

(2016) Xian Xia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Chromatin Remodelling Enzymes SNF2H and SNF2L Position Nucleosomes adjacent to CTCF and Other Transcription Factors

(2016) Nicola Wiechens et al.   PLoS Genetics

Stepwise nucleosome translocation by RSC remodeling complexes

(2016) Bryan T Harada et al.   eLife

SWI/SNF recruitment to a DNA double-strand break by the NuA4 and Gcn5 histone acetyltransferases

(2015) Gwendolyn Bennett et al.   DNA REPAIR

Assembly of the Arp5 (Actin-related Protein) Subunit Involved in Distinct INO80 Chromatin Remodeling Activities

(2015) Wei Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Nucleotide-Driven Switch Regulates Flanking DNA Length Sensing by a Dimeric Chromatin Remodeler

(2015) John D. Leonard et al.   MOLECULAR CELL

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC

(2015) Cynthia Tallant et al.   STRUCTURE

Structural analyses of the chromatin remodelling enzymes INO80-C and SWR-C

(2015) Shinya Watanabe et al.   Nature Communications

Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis

(2015) Mayuri Rege et al.   Cell Reports

H2A histone-fold and DNA elements in nucleosome activate SWR1-mediated H2A.Z replacement in budding yeast

(2015) Anand Ranjan et al.   eLife

The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism

(2015) Timothy J Parnell et al.   eLife

Regulating the Chromatin Landscape: Structural and Mechanistic Perspectives

(2014) Blaine Bartholomew   Annual Review of Biochemistry

Histone Chaperones: Assisting Histone Traffic and Nucleosome Dynamics

(2014) Zachary A. Gurard-Levin et al.   Annual Review of Biochemistry

Novel Mi-2 related ATP-dependent chromatin remodelers

(2014) Natascha Kunert et al.   Epigenetics

Swi/Snf dynamics on stress-responsive genes is governed by competitive bromodomain interactions

(2014) Arnob Dutta et al.   GENES & DEVELOPMENT

The Histone H4 Tail Regulates the Conformation of the ATP-Binding Pocket in the SNF2h Chromatin Remodeling Enzyme

(2014) Lisa R. Racki et al.   JOURNAL OF MOLECULAR BIOLOGY

The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer

(2014) Jingjun Hong et al.   MOLECULAR CELL

Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA

(2014) William L. Hwang et al.   NATURE

A long noncoding RNA protects the heart from pathological hypertrophy

(2014) Pei Han et al.   NATURE

ISWI Remodelling of Physiological Chromatin Fibres Acetylated at Lysine 16 of Histone H4

(2014) Henrike Klinker et al.   PLoS One

Direct interactions promote eviction of the Sir3 heterochromatin protein by the SWI/SNF chromatin remodeling enzyme

(2014) Benjamin J. Manning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the Rhp26ERCC6/CSBchromatin remodeler by a novel conserved leucine latch motif

(2014) Lanfeng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription

(2014) Vincenzo Di Cerbo et al.   eLife

Structure and Subunit Topology of the INO80 Chromatin Remodeler and Its Nucleosome Complex

(2013) Alessandro Tosi et al.   CELL

Mechanisms and Functions of ATP-Dependent Chromatin-Remodeling Enzymes

(2013) Geeta J. Narlikar et al.   CELL

ISWI Remodelers Slide Nucleosomes with Coordinated Multi-Base-Pair Entry Steps and Single-Base-Pair Exit Steps

(2013) Sebastian Deindl et al.   CELL

Molecular Architecture of the ATP-Dependent Chromatin-Remodeling Complex SWR1

(2013) Vu Q. Nguyen et al.   CELL

The NuRD architecture

(2013) Hillary F. Allen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

No need for a power stroke in ISWI-mediated nucleosome sliding

(2013) Johanna Ludwigsen et al.   EMBO REPORTS

DNA Looping Facilitates Targeting of a Chromatin Remodeling Enzyme

(2013) Adam N. Yadon et al.   MOLECULAR CELL

The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex

(2013) John R Prensner et al.   NATURE GENETICS

Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex

(2013) L. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler

(2013) Heidi L. Schubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Histone Acetylation Switch Regulates H2A.Z Deposition by the SWR-C Remodeling Enzyme

(2013) S. Watanabe et al.   SCIENCE

The bromodomain interaction module

(2012) Panagis Filippakopoulos et al.   FEBS LETTERS

The PHD and Chromo Domains Regulate the ATPase Activity of the Human Chromatin Remodeler CHD4

(2012) Aleksandra A. Watson et al.   JOURNAL OF MOLECULAR BIOLOGY

The SnAC Domain of SWI/SNF Is a Histone Anchor Required for Remodeling

(2012) P. Sen et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of ISWI involves inhibitory modules antagonized by nucleosomal epitopes

(2012) Cedric R. Clapier et al.   NATURE

The ATPase domain of ISWI is an autonomous nucleosome remodeling machine

(2012) Felix Mueller-Planitz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange

(2012) Michaela Smolle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Signals and Combinatorial Functions of Histone Modifications

(2011) Tamaki Suganuma et al.   Annual Review of Biochemistry

SnapShot: Chromatin Remodeling: INO80 and SWR1

(2011) Yunhe Bao et al.   CELL

SnapShot: Chromatin Remodeling: ISWI

(2011) Adam N. Yadon et al.   CELL

Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions

(2011) Alexander J. Ruthenburg et al.   CELL

Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity

(2011) Manolis Papamichos-Chronakis et al.   CELL

SnapShot: Chromatin Remodeling:SWI/SNF

(2011) Margaret M. Kasten et al.   CELL

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms

(2011) Diana C Hargreaves et al.   CELL RESEARCH

The RSC chromatin remodelling ATPase translocates DNA with high force and small step size

(2011) George Sirinakis et al.   EMBO JOURNAL

The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains

(2011) Daniel P Ryan et al.   EMBO JOURNAL

Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9

(2011) Robyn E. Mansfield et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subunit Organization of the Human INO80 Chromatin Remodeling Complex

(2011) Lu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extranucleosomal DNA Binding Directs Nucleosome Sliding by Chd1

(2011) J. N. McKnight et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of a Rapidly Formed Nonnucleosomal Histone-DNA Intermediate that Is Converted into Chromatin by ACF

(2011) Sharon E. Torigoe et al.   MOLECULAR CELL

esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function

(2011) Lena Ho et al.   NATURE CELL BIOLOGY

Histone H3 tail acetylation modulates ATP-dependent remodeling through multiple mechanisms

(2011) Nilanjana Chatterjee et al.   NUCLEIC ACIDS RESEARCH

The ISWI Chromatin Remodeler Organizes the hsrω ncRNA–Containing Omega Speckle Nuclear Compartments

(2011) Maria C. Onorati et al.   PLoS Genetics

Chromatin Regulatory Mechanisms in Pluripotency

(2010) Julie A. Lessard et al.   Annual Review of Cell and Developmental Biology

The ATP-Dependent Remodeler RSC Transfers Histone Dimers and Octamers through the Rapid Formation of an Unstable Encounter Intermediate

(2010) Claire E. Rowe et al.   BIOCHEMISTRY

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner

(2010) Martin J. Law et al.   CELL

Stepwise Histone Replacement by SWR1 Requires Dual Activation with Histone H2A.Z and Canonical Nucleosome

(2010) Ed Luk et al.   CELL

A cooperative activation loop among SWI/SNF, γ-H2AX and H3 acetylation for DNA double-strand break repair

(2010) Han-Sae Lee et al.   EMBO JOURNAL

Gcn5 regulates the dissociation of SWI/SNF from chromatin by acetylation of Swi2/Snf2

(2010) J.-H. Kim et al.   GENES & DEVELOPMENT

NuA4-dependent Acetylation of Nucleosomal Histones H4 and H2A Directly Stimulates Incorporation of H2A.Z by the SWR1 Complex

(2010) Mohammed Altaf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The INO80 ATP-Dependent Chromatin Remodeling Complex Is a Nucleosome Spacing Factor

(2010) M. Udugama et al.   MOLECULAR AND CELLULAR BIOLOGY

SWI/SNF Has Intrinsic Nucleosome Disassembly Activity that Is Dependent on Adjacent Nucleosomes

(2010) Mekonnen Lemma Dechassa et al.   MOLECULAR CELL

UV-Induced Association of the CSB Remodeling Protein with Chromatin Requires ATP-Dependent Relief of N-Terminal Autorepression

(2010) Robert J. Lake et al.   MOLECULAR CELL

The Chromodomains of the Chd1 Chromatin Remodeler Regulate DNA Access to the ATPase Motor

(2010) Glenn Hauk et al.   MOLECULAR CELL

Chromatin remodelling during development

(2010) Lena Ho et al.   NATURE

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Biology of Chromatin Remodeling Complexes

(2009) Cedric R. Clapier et al.   Annual Review of Biochemistry

Chromatin Remodeling by Imitation Switch (ISWI) Class ATP-dependent Remodelers Is Stimulated by Histone Variant H2A.Z

(2009) Joseph A. Goldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RVB1/RVB2: Running Rings around Molecular Biology

(2009) Sudhakar Jha et al.   MOLECULAR CELL

A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation

(2009) Heinz Neumann et al.   MOLECULAR CELL

The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes

(2009) Lisa R. Racki et al.   NATURE

Dynamics of nucleosome remodelling by individual ACF complexes

(2009) Timothy R. Blosser et al.   NATURE

H3.3/H2A.Z double variant–containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

(2009) Chunyuan Jin et al.   NATURE GENETICS

Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes

(2009) Ashby J Morrison et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nucleosomes can invade DNA territories occupied by their neighbors

(2009) Maik Engeholm et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nucleosome Retention and the Stochastic Nature of Promoter Chromatin Remodeling for Transcription

(2008) Hinrich Boeger et al.   CELL

The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus

(2008) Christine Mayer et al.   EMBO REPORTS

Structural basis of histone H4 recognition by p55

(2008) J.-J. Song et al.   GENES & DEVELOPMENT

SWI/SNF Mediates Polycomb Eviction and Epigenetic Reprogramming of the INK4b-ARF-INK4a Locus

(2008) S. K. Kia et al.   MOLECULAR AND CELLULAR BIOLOGY

Architecture of the SWI/SNF-Nucleosome Complex

(2008) M. L. Dechassa et al.   MOLECULAR AND CELLULAR BIOLOGY

Eaf1 Is the Platform for NuA4 Molecular Assembly That Evolutionarily Links Chromatin Acetylation to ATP-Dependent Exchange of Histone H2A Variants

(2008) A. Auger et al.   MOLECULAR AND CELLULAR BIOLOGY

The HSA domain binds nuclear actin-related proteins to regulate chromatin-remodeling ATPases

(2008) Heather Szerlong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of a RSC–nucleosome complex and insights into chromatin remodeling

(2008) Yuriy Chaban et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY