Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures

Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration

(2021) Dmitry Lim et al.   CELL CALCIUM

Endothelial signaling at the core of neurovascular coupling: The emerging role of endothelial inward-rectifier K+ (Kir2.1) channels and N-methyl-d-aspartate receptors in the regulation of cerebral blood flow

(2021) Sharon Negri et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Calcineurin Controls Expression of EAAT1/GLAST in Mouse and Human Cultured Astrocytes through Dynamic Regulation of Protein Synthesis and Degradation

(2020) Giulia Dematteis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Proteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice

(2020) Giulia Dematteis et al.   Cell Death & Disease

Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer’s disease mouse model

(2019) Francesca Rocchio et al.   Cell Death & Disease

The proteostasis network and its decline in ageing

(2019) Mark S. Hipp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Episodic memory: Neuronal codes for what, where, and when

(2019) Jørgen Sugar et al.   HIPPOCAMPUS

Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy

(2019) Annamaria Vezzani et al.   Nature Reviews Neurology

Astroglial atrophy in Alzheimer’s disease

(2019) Alexei Verkhratsky et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Deletion of calcineurin from GFAP‐expressing astrocytes impairs excitability of cerebellar and hippocampal neurons through astroglial Na + /K + ATPase

(2019) Laura Tapella et al.   GLIA

Role of astrocyte purinergic signaling in epilepsy

(2019) Ljiljana Nikolic et al.   GLIA

The emerging roles of protein homeostasis-governing pathways in Alzheimer's disease

(2018) Ji Cheng et al.   AGING CELL

Transcriptional remodeling in primary hippocampal astrocytes from an Alzheimer’s disease mouse model

(2018) F Ruffinatti et al.   Current Alzheimer Research

Mitochondria and Mitochondrial Cascades in Alzheimer’s Disease

(2018) Russell H. Swerdlow   JOURNAL OF ALZHEIMERS DISEASE

Alterations of Hippocampal Myelin Sheath and Axon Sprouting by Status Convulsion and Regulating Lingo-1 Expression with RNA Interference in Immature and Adult Rats

(2018) Xiao-Jie Song et al.   NEUROCHEMICAL RESEARCH

Review: Neuroinflammatory pathways as treatment targets and biomarker candidates in epilepsy: emerging evidence from preclinical and clinical studies

(2018) E. A. van Vliet et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Physiology of Astroglia

(2018) Alexei Verkhratsky et al.   PHYSIOLOGICAL REVIEWS

Proteomic analysis of human epileptic neocortex predicts vascular and glial changes in epileptic regions

(2018) Gal Keren-Aviram et al.   PLoS One

A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease

(2018) Estela Area-Gomez et al.   Cell Death & Disease

Subtle Alterations in Spatial Memory Induced by Amyloid Peptides Infusion in Rats

(2018) Priscila Tavares Macêdo et al.   Frontiers in Aging Neuroscience

The Barnes Maze Task Reveals Specific Impairment of Spatial Learning Strategy in the Intrahippocampal Kainic Acid Model for Temporal Lobe Epilepsy

(2018) Yana Van Den Herrewegen et al.   NEUROCHEMICAL RESEARCH

Glutamate triggers intracellular Ca2+ oscillations and nitric oxide release by inducing NAADP- and InsP3 -dependent Ca2+ release in mouse brain endothelial cells

(2018) Estella Zuccolo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Assessment of spatial learning and memory in the Barnes maze task in rodents—methodological consideration

(2018) Kinga Gawel et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Interictal oscillations and focal epileptic disorders

(2017) Maxime Lévesque et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: An in depth proteomic study

(2017) Elisa Dalla Pozza et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Calcineurin signaling in the heart: The importance of time and place

(2017) Valentina Parra et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Epileptic activity in Alzheimer's disease: causes and clinical relevance

(2017) Keith A Vossel et al.   LANCET NEUROLOGY

Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

(2017) Thomas A Longden et al.   NATURE NEUROSCIENCE

On the Integration of Space, Time, and Memory

(2017) Howard Eichenbaum   NEURON

Three-dimensional Ca2+imaging advances understanding of astrocyte biology

(2017) Erika Bindocci et al.   SCIENCE

Drug-Resistant Epilepsy: Multiple Hypotheses, Few Answers

(2017) Fei Tang et al.   Frontiers in Neurology

Calcium signaling in skeletal muscle development, maintenance and regeneration

(2016) Michelle K. Tu et al.   CELL CALCIUM

Calcium Signalling Toolkits in Astrocytes and Spatio-Temporal Progression of Alzheimer's Disease

(2016) Dmitry Lim et al.   Current Alzheimer Research

Astroglia dynamics in ageing and Alzheimer's disease

(2016) Alexei Verkhratsky et al.   CURRENT OPINION IN PHARMACOLOGY

HMGB1 Osteo-Modulatory Action on Osteosarcoma SaOS-2 Cell Line: An Integrated Study From Biochemical and -Omics Approaches

(2016) Simona Martinotti et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

(2016) Sebastien Paillusson et al.   TRENDS IN NEUROSCIENCES

Calcineurin Links Mitochondrial Elongation with Energy Metabolism

(2015) Paul T. Pfluger et al.   Cell Metabolism

Diversity of astrocyte functions and phenotypes in neural circuits

(2015) Baljit S Khakh et al.   NATURE NEUROSCIENCE

Calcineurin and glial signaling: neuroinflammation and beyond

(2014) Jennifer L Furman et al.   Journal of Neuroinflammation

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction

(2014) Marie Orre et al.   NEUROBIOLOGY OF AGING

Altered hippocampal myelinated fiber integrity in a lithium-pilocarpine model of temporal lobe epilepsy: A histopathological and stereological investigation

(2013) Yuanzhen Ye et al.   BRAIN RESEARCH

Genetics of dementia

(2013) Clement T Loy et al.   LANCET

Complex and region-specific changes in astroglial markers in the aging brain

(2013) José J. Rodríguez et al.   NEUROBIOLOGY OF AGING

Rigid firing sequences undermine spatial memory codes in a neurodegenerative mouse model

(2013) Jingheng Cheng et al.   eLife

Neuronal excitability and calcium/calmodulin-dependent protein kinase type II: Location, location, location

(2012) Xiao-Bo Liu et al.   EPILEPSIA

Neural functions of calcineurin in synaptic plasticity and memory

(2012) K. Baumgartel et al.   LEARNING & MEMORY

Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology

(2011) A M Fernandez et al.   MOLECULAR PSYCHIATRY

Assessment of spatial memory in mice

(2010) Sunita Sharma et al.   LIFE SCIENCES

Transcriptional regulation of bone and joint remodeling by NFAT

(2009) Despina Sitara et al.   IMMUNOLOGICAL REVIEWS

Pten Deletion in Adult Neural Stem/Progenitor Cells Enhances Constitutive Neurogenesis

(2009) C. Gregorian et al.   JOURNAL OF NEUROSCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Sorting Out Astrocyte Physiology from Pharmacology

(2008) Todd A. Fiacco et al.   Annual Review of Pharmacology and Toxicology

Calcium signaling in lymphocytes

(2008) Masatsugu Oh-hora et al.   CURRENT OPINION IN IMMUNOLOGY

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

(2008) G. M. Cereghetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA