Integrated omics analysis reveals sirtuin signaling is central to hepatic response to a high fructose diet

SIRT2 Prevents Liver Steatosis and Metabolic Disorders via Deacetylation of HNF4α

(2021) Huihui Ren et al.   HEPATOLOGY

Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology

(2021) Vincent L. Chen et al.   Nature Communications

Aging‐related Alzheimer's disease‐like neuropathology and functional decline in captive vervet monkeys ( Chlorocebus aethiops sabaeus )

(2021) Brett M. Frye et al.   AMERICAN JOURNAL OF PRIMATOLOGY

Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity

(2020) Marion Régnier et al.   Scientific Reports

Melanocytes Sense Blue Light and Regulate Pigmentation through Opsin-3

(2018) Claire Regazzetti et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Integrated Omics: Tools, Advances, and Future Approaches

(2018) Biswapriya B Misra et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Primate fetal hepatic responses to maternal obesity: epigenetic signalling pathways and lipid accumulation

(2018) Sobha Puppala et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neurodegenerative disease biomarkers Aβ1-40 , Aβ1-42 , tau, and p-tau181 in the vervet monkey cerebrospinal fluid: Relation to normal aging, genetic influences, and cerebral amyloid angiopathy

(2018) Jason A. Chen et al.   Brain and Behavior

Greater Microbial Translocation and Vulnerability to Metabolic Disease in Healthy Aged Female Monkeys

(2018) Quentin N. Wilson et al.   Scientific Reports

Sex-specific differences in hepatic steatosis in obese spontaneously hypertensive (SHROB) rats

(2018) Qingming Dong et al.   Biology of Sex Differences

A nonhuman primate model of early Alzheimer's disease pathologic change: Implications for disease pathogenesis

(2018) Caitlin S. Latimer et al.   Alzheimers & Dementia

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity: a pilot study

(2017) L Hodson et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Obesity and obesogenic growth are both highly heritable and modified by diet in a nonhuman primate model, the African green monkey (Chlorocebus aethiops sabaeus)

(2017) C A Schmitt et al.   INTERNATIONAL JOURNAL OF OBESITY

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

(2017) Samir Softic et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate

(2017) Anna J Jasinska et al.   NATURE GENETICS

Regulators of mitochondrial quality control differ in subcutaneous fat of metabolically healthy and unhealthy obese monkeys

(2017) Kylie Kavanagh et al.   Obesity

Fatty liver promotes fibrosis in monkeys consuming high fructose

(2017) Michael A. Cydylo et al.   Obesity

Resveratrol and caloric restriction prevent hepatic steatosis by regulating SIRT1-autophagy pathway and alleviating endoplasmic reticulum stress in high-fat diet-fed rats

(2017) Shibin Ding et al.   PLoS One

Serum aminotransferases in nonalcoholic fatty liver disease are a signature of liver metabolic perturbations at the amino acid and Krebs cycle level1,2

(2016) Silvia Sookoian et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH

(2016) Kimberley D. Bruce et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids

(2016) Takamasa Tobita et al.   PLoS One

Sirtuins and nonalcoholic fatty liver disease

(2016) Fatiha Nassir et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

(2016) Francesca Sacco et al.   Nature Communications

Chronic oxytocin administration inhibits food intake, increases energy expenditure, and produces weight loss in fructose-fed obese rhesus monkeys

(2015) James E. Blevins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The genome of the vervet (Chlorocebus aethiops sabaeus)

(2015) Wesley C. Warren et al.   GENOME RESEARCH

Comparison of GC-MS and GC×GC-MS in the Analysis of Human Serum Samples for Biomarker Discovery

(2015) Jason H. Winnike et al.   JOURNAL OF PROTEOME RESEARCH

A Potential Treatment of Nonalcoholic Fatty Liver Disease with SIRT1 Activators

(2014)   Journal of Gastrointestinal and Liver Diseases

Fatty acid chain length and saturation influences PPARα transcriptional activation and repression in HepG2 cells

(2014) Herman E. Popeijus et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Baboon Kidney Transcriptome: Analysis of Transcript Sequence, Splice Variants, and Abundance

(2014) Kimberly D. Spradling et al.   PLoS One

Dietary fructose induces endotoxemia and hepatic injury in calorically controlled primates

(2013) Kylie Kavanagh et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Significant Genotype by Diet (G × D) Interaction Effects on Cardiometabolic Responses to a Pedigree-Wide, Dietary Challenge in Vervet Monkeys (Chlorocebus aethiops sabaeus)

(2013) VENKATA S. VORUGANTI et al.   AMERICAN JOURNAL OF PRIMATOLOGY

Development of amyloid burden in African Green monkeys

(2013) Sergey Kalinin et al.   NEUROBIOLOGY OF AGING

Effects of fructose and glucose overfeeding on hepatic insulin sensitivity and intrahepatic lipids in healthy humans

(2013) V. Lecoultre et al.   Obesity

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(2012) X. Jiao et al.   BIOINFORMATICS

Differential microRNA response to a high-cholesterol, high-fat diet in livers of low and high LDL-C baboons

(2012) Genesio M Karere et al.   BMC GENOMICS

25(OH)D3 and Cardiovascular Risk Factors in Female Nonhuman Primates

(2012) Matthew J. Jorgensen et al.   JOURNAL OF WOMENS HEALTH

Aging Does Not Reduce Heat Shock Protein 70 in the Absence of Chronic Insulin Resistance

(2012) K. Kavanagh et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Omega-3 Polyunsaturated Fatty Acids Antagonize Macrophage Inflammation via Activation of AMPK/SIRT1 Pathway

(2012) Bingzhong Xue et al.   PLoS One

Fructose-Fed Rhesus Monkeys: A Nonhuman Primate Model of Insulin Resistance, Metabolic Syndrome, and Type 2 Diabetes

(2011) Andrew A. Bremer et al.   CTS-Clinical and Translational Science

Ras/Mitogen-activated Protein Kinase (MAPK) Signaling Modulates Protein Stability and Cell Surface Expression of Scavenger Receptor SR-BI

(2011) Peta Wood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2011) Peter Libby et al.   NATURE

Waterborne manganese exposure alters plasma, brain, and liver metabolites accompanied by changes in stereotypic behaviors

(2011) Steve Fordahl et al.   NEUROTOXICOLOGY AND TERATOLOGY

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation

(2010) Feng-Ming Wang et al.   BIOCHEMICAL JOURNAL

Health implications of fructose consumption: A review of recent data

(2010) Salwa W Rizkalla   Nutrition & Metabolism

Metabonomic Variations in the Drug-Treated Type 2 Diabetes Mellitus Patients and Healthy Volunteers

(2009) Yuqian Bao et al.   JOURNAL OF PROTEOME RESEARCH

Serum Metabolite Profiling of Human Colorectal Cancer Using GC−TOFMS and UPLC−QTOFMS

(2009) Yunping Qiu et al.   JOURNAL OF PROTEOME RESEARCH

Analysis of transcriptome and metabolome profiles alterations in fatty liver induced by high-fat diet in rat

(2009) Zuoquan Xie et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity

(2009) E. Fabbrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocrine and metabolic effects of consuming beverages sweetened with fructose, glucose, sucrose, or high-fructose corn syrup

(2008) Kimber L Stanhope et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Discovering microRNAs from deep sequencing data using miRDeep

(2008) Marc R Friedländer et al.   NATURE BIOTECHNOLOGY