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Title
Dosing extracellular vesicles
Authors
Keywords
Exosome, Drug delivery, EV therapeutics, Engineered EVs, Therapeutic dosing
Journal
ADVANCED DRUG DELIVERY REVIEWS
Volume 178, Issue -, Pages 113961
Publisher
Elsevier BV
Online
2021-09-02
DOI
10.1016/j.addr.2021.113961
References
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Note: Only part of the references are listed.- Engineering exosomes for pulmonary delivery of peptides and drugs to inflammatory lung cells by inhalation
- (2021) GyeungYun Kim et al. JOURNAL OF CONTROLLED RELEASE
- The biology, function, and biomedical applications of exosomes
- (2020) Raghu Kalluri et al. SCIENCE
- Functional extracellular vesicles aplenty
- (2020) Antje M. Zickler et al. Nature Biomedical Engineering
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- (2020) Li Yang et al. CIRCULATION
- Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality
- (2020) Hojun Choi et al. Science Advances
- Extracellular Vesicles From Adipose Tissue-Derived Stem Cells Affect Notch-miR148a-3p Axis to Regulate Polarization of Macrophages and Alleviate Sepsis in Mice
- (2020) Xiaozhi Bai et al. Frontiers in Immunology
- Exosomes secreted by hiPSC-derived cardiac cells improve recovery from myocardial infarction in swine
- (2020) Ling Gao et al. Science Translational Medicine
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- (2020) Jiacheng Sun et al. Stem Cell Research & Therapy
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- (2020) Nuruddeen D. Lewis et al. MOLECULAR CANCER THERAPEUTICS
- Golden Exosomes Selectively Target Brain Pathologies in Neurodegenerative and Neurodevelopmental Disorders
- (2019) Nisim Perets et al. NANO LETTERS
- Stem Cell-Derived Exosomes as Nanotherapeutics for Autoimmune and Neurodegenerative Disorders
- (2019) Milad Riazifar et al. ACS Nano
- Advances in therapeutic applications of extracellular vesicles
- (2019) Oscar P. B. Wiklander et al. Science Translational Medicine
- High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer
- (2019) Aizea Morales-Kastresana et al. Journal of Extracellular Vesicles
- Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule – single vesicle level by fluorescence correlation spectroscopy and single particle imaging
- (2019) Giulia Corso et al. Journal of Extracellular Vesicles
- Extracellular vesicles mediate neuroprotection and functional recovery after traumatic brain injury
- (2019) Min Kyoung Sun et al. JOURNAL OF NEUROTRAUMA
- Exosomes Derived From M2b Macrophages Attenuate DSS-Induced Colitis
- (2019) Ruibing Yang et al. Frontiers in Immunology
- Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation
- (2019) Zhaogang Yang et al. Nature Biomedical Engineering
- Protein Profiling and Sizing of Extracellular Vesicles from Colorectal Cancer Patients via Flow Cytometry
- (2018) Ye Tian et al. ACS Nano
- Modified Exosomes Reduce Apoptosis and Ameliorate Neural Deficits Induced by Traumatic Brain Injury
- (2018) Bo Wang et al. ASAIO JOURNAL
- Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy
- (2018) Tian Tian et al. BIOMATERIALS
- Mesenchymal stromal cell exosome–enhanced regulatory T-cell production through an antigen-presenting cell–mediated pathway
- (2018) Bin Zhang et al. CYTOTHERAPY
- Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation
- (2018) Haiying Zhang et al. NATURE CELL BIOLOGY
- Shedding light on the cell biology of extracellular vesicles
- (2018) Guillaume van Niel et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Efficient RNA drug delivery using red blood cell extracellular vesicles
- (2018) Waqas Muhammad Usman et al. Nature Communications
- Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility
- (2018) Jayesh A. Kulkarni et al. Nucleic Acid Therapeutics
- Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model
- (2018) Mahesh Khatri et al. Stem Cell Research & Therapy
- Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide
- (2018) Adam Vandergriff et al. Theranostics
- Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures
- (2018) Oscar P. B. Wiklander et al. Frontiers in Immunology
- Dosage thresholds and influence of transgene cassette in AAV-related toxicity
- (2018) Hanen Khabou et al. HUMAN GENE THERAPY
- Dopamine-loaded blood exosomes targeted to brain for better treatment of Parkinson's disease
- (2018) Mengke Qu et al. JOURNAL OF CONTROLLED RELEASE
- Exosomes Isolated From Human Umbilical Cord Mesenchymal Stem Cells Alleviate Neuroinflammation and Reduce Amyloid-Beta Deposition by Modulating Microglial Activation in Alzheimer’s Disease
- (2018) Mao Ding et al. NEUROCHEMICAL RESEARCH
- Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome
- (2018) Helena Sork et al. Scientific Reports
- Engineered Exosomes With Ischemic Myocardium‐Targeting Peptide for Targeted Therapy in Myocardial Infarction
- (2018) Xu Wang et al. Journal of the American Heart Association
- Separation of virus-like particles and extracellular vesicles by flow-through and heparin affinity chromatography
- (2018) Katrin Reiter et al. JOURNAL OF CHROMATOGRAPHY A
- In Vitro Macrophage Assay Predicts the In Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells
- (2018) Natalia Pacienza et al. Molecular Therapy-Methods & Clinical Development
- Small But Increasingly Mighty: Latest Advances in AAV Vector Research, Design, and Evolution
- (2017) Dirk Grimm et al. HUMAN GENE THERAPY
- Higher functionality of extracellular vesicles isolated using size-exclusion chromatography compared to ultracentrifugation
- (2017) Emma A. Mol et al. Nanomedicine-Nanotechnology Biology and Medicine
- Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
- (2017) Sushrut Kamerkar et al. NATURE
- EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research
- (2017) Jan Van Deun et al. NATURE METHODS
- Graft-Versus-Host Disease Amelioration by Human Bone Marrow Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles Is Associated with Peripheral Preservation of Naive T Cell Populations
- (2017) Sumie Fujii et al. STEM CELLS
- Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo Chronic Myelogenous Leukemia cell growth
- (2017) Daniele Bellavia et al. Theranostics
- Nanoplasmonic quantification of tumour-derived extracellular vesicles in plasma microsamples for diagnosis and treatment monitoring
- (2017) Kai Liang et al. Nature Biomedical Engineering
- Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography
- (2017) Giulia Corso et al. Scientific Reports
- A bead-assisted flow cytometry method for the semi-quantitative analysis of Extracellular Vesicles
- (2017) Henar Suárez et al. Scientific Reports
- Microparticles as biomarkers of lung disease: enumeration in biological fluids using lipid bilayer microspheres
- (2016) Mark J. McVey et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Radiolabeling of Extracellular Vesicles with99mTc for QuantitativeIn VivoImaging Studies
- (2016) Zoltán Varga et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
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- (2016) L. Rivoltini et al. CLINICAL CANCER RESEARCH
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- (2016) Haibo Liu et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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- (2016) S. Cointe et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
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- Immuno-based detection of extracellular vesicles in urine as diagnostic marker for prostate cancer
- (2015) Diederick Duijvesz et al. INTERNATIONAL JOURNAL OF CANCER
- Exosomes as drug delivery vehicles for Parkinson's disease therapy
- (2015) Matthew J. Haney et al. JOURNAL OF CONTROLLED RELEASE
- Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics
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- Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury
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- Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties
- (2015) Joel Z. Nordin et al. Nanomedicine-Nanotechnology Biology and Medicine
- Improved Characterization of EV Preparations Based on Protein to Lipid Ratio and Lipid Properties
- (2015) Xabier Osteikoetxea et al. PLoS One
- Chromatographically isolated CD63+CD81+extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI
- (2015) Dong-ki Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lectin-induced agglutination method of urinary exosomes isolation followed by mi-RNA analysis: Application for prostate cancer diagnostic
- (2015) Roman Samsonov et al. PROSTATE
- A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure
- (2015) Georgia K. Atkin-Smith et al. Nature Communications
- Heparin affinity purification of extracellular vesicles
- (2015) Leonora Balaj et al. Scientific Reports
- Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR)
- (2015) Xavier Gallart-Palau et al. Scientific Reports
- Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression
- (2015) Thorsten R. Doeppner et al. Stem Cells Translational Medicine
- Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing
- (2015) Rebecca E. Lane et al. Scientific Reports
- Determination of Exosome Concentration in Solution Using Surface Plasmon Resonance Spectroscopy
- (2014) Déborah L. M. Rupert et al. ANALYTICAL CHEMISTRY
- Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction
- (2014) L. Barile et al. CARDIOVASCULAR RESEARCH
- Benchtop isolation and characterization of functional exosomes by sequential filtration
- (2014) Mitja L. Heinemann et al. JOURNAL OF CHROMATOGRAPHY A
- A novel “salting-out” procedure for the isolation of tumor-derived exosomes
- (2014) Zachary Brownlee et al. JOURNAL OF IMMUNOLOGICAL METHODS
- A simple flow cytometry method improves the detection of phosphatidylserine-exposing extracellular vesicles
- (2014) N. Arraud et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration
- (2014) N. Arraud et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing
- (2014) E. van der Pol et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease
- (2014) L Kordelas et al. LEUKEMIA
- AAV Empty Capsids: For Better or for Worse?
- (2014) J Fraser Wright MOLECULAR THERAPY
- Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice
- (2014) J. Mark Cooper et al. MOVEMENT DISORDERS
- Rapid Isolation of Extracellular Vesicles from Cell Culture and Biological Fluids Using a Synthetic Peptide with Specific Affinity for Heat Shock Proteins
- (2014) Anirban Ghosh et al. PLoS One
- A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy
- (2013) Yanhua Tian et al. BIOMATERIALS
- Serum exosomes in pregnancy-associated immune modulation and neuroprotection during CNS autoimmunity
- (2013) Jessica L. Williams et al. CLINICAL IMMUNOLOGY
- A trigger channel threshold artifact in nanoparticle analysis
- (2013) John P. Nolan et al. CYTOMETRY PART A
- Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model
- (2013) Suyan Bian et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Quantification of nanosized extracellular membrane vesicles with scanning ion occlusion sensing
- (2013) Jeroen de Vrij et al. Nanomedicine
- Extracellular vesicles: biology and emerging therapeutic opportunities
- (2013) Samir EL Andaloussi et al. NATURE REVIEWS DRUG DISCOVERY
- Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
- (2013) Fatih Arslan et al. Stem Cell Research
- Single vs. swarm detection of microparticles and exosomes by flow cytometry
- (2012) E. Van Der POL et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes
- (2012) Bow J. Tauro et al. METHODS
- Exosome-mediated delivery of siRNA in vitro and in vivo
- (2012) Samir El-Andaloussi et al. Nature Protocols
- Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry
- (2012) Els J van der Vlist et al. Nature Protocols
- Recovery of urinary nanovesicles from ultracentrifugation supernatants
- (2012) Luca Musante et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy
- (2011) Viktoriya Sokolova et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- A filtration-based protocol to isolate human Plasma Membrane-derived Vesicles and exosomes from blood plasma
- (2011) Ryan Grant et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Allometric scaling of pegylated liposomal anticancer drugs
- (2011) Whitney P. Caron et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain
- (2011) Xiaoying Zhuang et al. MOLECULAR THERAPY
- Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis
- (2011) Rebecca A. Dragovic et al. Nanomedicine-Nanotechnology Biology and Medicine
- Quantitative and qualitative flow cytometric analysis of nanosized cell-derived membrane vesicles
- (2011) Esther N.M. Nolte-'t Hoen et al. Nanomedicine-Nanotechnology Biology and Medicine
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
- (2011) Kasey C. Vickers et al. NATURE CELL BIOLOGY
- Characterization of extracellular circulating microRNA
- (2011) Andrey Turchinovich et al. NUCLEIC ACIDS RESEARCH
- Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
- (2011) J. D. Arroyo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction
- (2011) Leo Timmers et al. Stem Cell Research
- Structural-Mechanical Characterization of Nanoparticle Exosomes in Human Saliva, Using Correlative AFM, FESEM, and Force Spectroscopy
- (2010) Shivani Sharma et al. ACS Nano
- Microfiltration isolation of human urinary exosomes for characterization by MS
- (2010) Michael L. Merchant et al. Proteomics Clinical Applications
- Exosomes derived from interleukin-10-treated dendritic cells can inhibit trinitrobenzene sulfonic acid-induced rat colitis
- (2010) Xiaojun Yang et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
- (2010) Ruenn Chai Lai et al. Stem Cell Research
- Membrane-bound HSP70-engineered myeloma cell-derived exosomes stimulate more efficient CD8+ CTL- and NK-mediated antitumour immunity than exosomes released from heat-shocked tumour cells expressing cytoplasmic HSP70
- (2009) Yufeng Xie et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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