Protein Corona Inhibits Endosomal Escape of Functionalized DNA Nanostructures in Living Cells

DNA Nanodevices with Selective Immune Cell Interaction and Function

(2021) Nishkantha Arulkumaran et al.   ACS Nano

Key principles and methods for studying the endocytosis of biological and nanoparticle therapeutics

(2021) Joshua J. Rennick et al.   Nature Nanotechnology

Advanced preclinical models for evaluation of drug-induced liver injury – consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET]

(2021) Jose C. Fernandez-Checa et al.   JOURNAL OF HEPATOLOGY

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

(2020) Yi-Hsien Cheng et al.   ACS Nano

The entry of nanoparticles into solid tumours

(2020) Shrey Sindhwani et al.   NATURE MATERIALS

Effect of Protein Corona on The Transfection Efficiency of Lipid-Coated Graphene Oxide-Based Cell Transfection Reagents

(2020) Erica Quagliarini et al.   Pharmaceutics

Programming Cell–Cell Communications with Engineered Cell Origami Clusters

(2020) Zhilei Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The success of nanomedicine

(2020) Twan Lammers et al.   Nano Today

Tutorial: guidance for quantitative confocal microscopy

(2020) James Jonkman et al.   Nature Protocols

Iron Oxide Nanoparticle-Induced Autophagic Flux Is Regulated by Interplay between p53-mTOR Axis and Bcl-2 Signaling in Hepatic Cells

(2020) Mariia Uzhytchak et al.   Cells

Role of nanoscale antigen organization on B-cell activation probed using DNA origami

(2020) Rémi Veneziano et al.   Nature Nanotechnology

Direct Functional Protein Delivery with a Peptide into Neonatal and Adult Mammalian Inner Ear In Vivo

(2020) Kun Zhang et al.   Molecular Therapy-Methods & Clinical Development

Analyzing the mechanisms of iron oxide nanoparticles interactions with cells: A road from failure to success in clinical applications

(2020) Adam Frtús et al.   JOURNAL OF CONTROLLED RELEASE

Hepatic Tumor Cell Morphology Plasticity under Physical Constraints in 3D Cultures Driven by YAP–mTOR Axis

(2020) Adam Frtús et al.   Pharmaceuticals

Delivering DNA origami to cells

(2019) Dhanasekaran Balakrishnan et al.   Nanomedicine

Cholesterol Anchors Enable Efficient Binding and Intracellular Uptake of DNA Nanostructures

(2019) William L. Whitehouse et al.   BIOCONJUGATE CHEMISTRY

The beginning of the end of the nanomedicine hype

(2019) Kinam Park   JOURNAL OF CONTROLLED RELEASE

Light-induced modulation of the mitochondrial respiratory chain activity: possibilities and limitations

(2019) Mariia Lunova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Smart cancer nanomedicine

(2019) Roy van der Meel et al.   Nature Nanotechnology

Remote Actuation of Apoptosis in Liver Cancer Cells via Magneto-Mechanical Modulation of Iron Oxide Nanoparticles

(2019) Oleg Lunov et al.   Cancers

Reconstructed chitosan with alkylamine for enhanced gene delivery by promoting endosomal escape

(2019) Guojun Huang et al.   CARBOHYDRATE POLYMERS

A Flow Cytometric Method to Quantify the Endosomal Escape of a Protein Toxin to the Cytosol of Target Cells

(2019) Harrison J. Wensley et al.   PHARMACEUTICAL RESEARCH

Defined Bilayer Interactions of DNA Nanopores Revealed with a Nuclease-Based Nanoprobe Strategy

(2018) Jonathan R. Burns et al.   ACS Nano

Visualization of the Cellular Uptake and Trafficking of DNA Origami Nanostructures in Cancer Cells

(2018) Pengfei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A beginner’s guide to rigor and reproducibility in fluorescence imaging experiments

(2018) Jen-Yi Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape

(2018) Maartje M. C. Bastings et al.   NANO LETTERS

Multi-functional DNA nanostructures that puncture and remodel lipid membranes into hybrid materials

(2018) Oliver Birkholz et al.   Nature Communications

Detailed investigation on how the protein corona modulates the physicochemical properties and gene delivery of polyethylenimine (PEI) polyplexes

(2018) Dingcheng Zhu et al.   Biomaterials Science

Cellular Uptake of Nanoparticles versus Small Molecules: A Matter of Size

(2018) Jesús Mosquera et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enhanced endosomal escape by photothermal activation for improved small interfering RNA delivery and antitumor effect

(2018) Xi Yang et al.   International Journal of Nanomedicine

Overcoming Endosomal Entrapment in Drug Delivery

(2018) Dehua Pei et al.   BIOCONJUGATE CHEMISTRY

Quantitative Analysis of the Correlation between Cell Size and Cellular Uptake of Particles

(2018) Jawahar Khetan et al.   BIOPHYSICAL JOURNAL

Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria

(2017) Julianna D. Zeidler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-targetable DNA nanocapsules for spatiotemporal release of caged bioactive small molecules

(2017) Aneesh T. Veetil et al.   Nature Nanotechnology

Tenovin-6 impairs autophagy by inhibiting autophagic flux

(2017) Hongfeng Yuan et al.   Cell Death & Disease

Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

(2017) Nandhini Ponnuswamy et al.   Nature Communications

The Beauty and Utility of DNA Origami

(2017) Pengfei Wang et al.   Chem

Curvature and Rho activation differentially control the alignment of cells and stress fibers

(2017) Nathan D. Bade et al.   Science Advances

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis

(2017) Nuria Andreu et al.   Scientific Reports

Nanoparticle core stability and surface functionalization drive the mTOR signaling pathway in hepatocellular cell lines

(2017) Mariia Lunova et al.   Scientific Reports

Cellular processing and destinies of artificial DNA nanostructures

(2016) Di Sheng Lee et al.   CHEMICAL SOCIETY REVIEWS

Modulation of collective cell behaviour by geometrical constraints

(2016) Mariia Lunova et al.   Integrative Biology

Understanding the nanoparticle–protein corona complexes using computational and experimental methods

(2016) B. Kharazian et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?

(2016) F. Danhier   JOURNAL OF CONTROLLED RELEASE

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

(2016) Yi-Nan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced protein internalization and efficient endosomal escape using polyampholyte-modified liposomes and freeze concentration

(2016) Sana Ahmed et al.   Nanoscale

Recent Advances in Shape-Controlled Synthesis of Noble Metal Nanoparticles by Radiolysis Route

(2016) Alam Abedini et al.   Nanoscale Research Letters

Engineering and mapping nanocavity emission via precision placement of DNA origami

(2016) Ashwin Gopinath et al.   NATURE

Mechanism of hard-nanomaterial clearance by the liver

(2016) Kim M. Tsoi et al.   NATURE MATERIALS

A biomimetic DNA-based channel for the ligand-controlled transport of charged molecular cargo across a biological membrane

(2016) Jonathan R. Burns et al.   Nature Nanotechnology

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Designer nanoscale DNA assemblies programmed from the top down

(2016) R. Veneziano et al.   SCIENCE

Recent Advances in Shape-Controlled Synthesis of Noble Metal Nanoparticles by Radiolysis Route

(2016) Alam Abedini et al.   Nanoscale Research Letters

Quantitating the cell: turning images into numbers with ImageJ

(2016) Ellen T Arena et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Controlling Size, Morphology, and Surface Composition of AgAu Nanodendrites in 15 s for Improved Environmental Catalysis under Low Metal Loadings

(2015) Anderson G. M. da Silva et al.   ACS Applied Materials & Interfaces

Growth and Origami Folding of DNA on Nanoparticles for High-Efficiency Molecular Transport in Cellular Imaging and Drug Delivery

(2015) Juan Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Towards understanding of nanoparticle–protein corona

(2015) Cuicui Ge et al.   ARCHIVES OF TOXICOLOGY

Discovery and Characterization of a Peptide That Enhances Endosomal Escape of Delivered Proteins in Vitro and in Vivo

(2015) Margie Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ultrafast superresolution fluorescence imaging with spinning disk confocal microscope optics

(2015) Shinichi Hayashi et al.   MOLECULAR BIOLOGY OF THE CELL

PSMA-mediated endosome escape-accelerating polymeric micelles for targeted therapy of prostate cancer and the real time tracing of their intracellular trafficking

(2015) Yajie Gao et al.   Nanoscale

DNA rendering of polyhedral meshes at the nanoscale

(2015) Erik Benson et al.   NATURE

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Routing of individual polymers in designed patterns

(2015) Jakob Bach Knudsen et al.   Nature Nanotechnology

Complex wireframe DNA origami nanostructures with multi-arm junction vertices

(2015) Fei Zhang et al.   Nature Nanotechnology

Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug-Resistance Mechanisms in a Leukemia Model

(2015) Patrick D. Halley et al.   Small

DNA Nanostructures as Smart Drug-Delivery Vehicles and Molecular Devices

(2015) Veikko Linko et al.   TRENDS IN BIOTECHNOLOGY

Cell-Size Control

(2015) Amanda A. Amodeo et al.   Cold Spring Harbor Perspectives in Biology

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

(2014) Qian Zhang et al.   ACS Nano

Addressing the Instability of DNA Nanostructures in Tissue Culture

(2014) Jaeseung Hahn et al.   ACS Nano

HCC cells with high levels of Bcl-2 are resistant to ABT-737 via activation of the ROS–JNK–autophagy pathway

(2014) Zhenhong Ni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Virus-Encapsulated DNA Origami Nanostructures for Cellular Delivery

(2014) Joona Mikkilä et al.   NANO LETTERS

Intracellular delivery of nanomaterials: How to catch endosomal escape in the act

(2014) Thomas F. Martens et al.   Nano Today

Mapping the Thermal Behavior of DNA Origami Nanostructures

(2013) Xixi Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Artifacts of light

(2013)   NATURE METHODS

Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle

(2013) Shruti R Saptarshi et al.   JOURNAL OF NANOBIOTECHNOLOGY

Protein corona formation around nanoparticles – from the past to the future

(2013) Pablo del Pino et al.   Materials Horizons

Cancer nanomedicines: So many papers and so few drugs!

(2012) Vincent J. Venditto et al.   ADVANCED DRUG DELIVERY REVIEWS

Visualization of the intracellular location and stability of DNA origami with a label-free fluorescent probe

(2012) Xibo Shen et al.   CHEMICAL COMMUNICATIONS

Synthetic Lipid Membrane Channels Formed by Designed DNA Nanostructures

(2012) M. Langecker et al.   SCIENCE

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Cellular Immunostimulation by CpG-Sequence-Coated DNA Origami Structures

(2011) Verena J. Schüller et al.   ACS Nano

Differential Uptake of Functionalized Polystyrene Nanoparticles by Human Macrophages and a Monocytic Cell Line

(2011) Oleg Lunov et al.   ACS Nano

DNA Cage Delivery to Mammalian Cells

(2011) Anthony S. Walsh et al.   ACS Nano

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Stability of DNA Origami Nanoarrays in Cell Lysate

(2011) Qian Mei et al.   NANO LETTERS

DNA Origami with Complex Curvatures in Three-Dimensional Space

(2011) D. Han et al.   SCIENCE

Cellular Response of Polyvalent Oligonucleotide−Gold Nanoparticle Conjugates

(2010) Matthew D. Massich et al.   ACS Nano

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

(2010) L. Guo et al.   DRUG METABOLISM AND DISPOSITION

Enhanced resistance of DNA nanostructures to enzymatic digestion

(2009) Jung-Won Keum et al.   CHEMICAL COMMUNICATIONS

A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester

(2009) Michael Miksa et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Quantification and its Applications in Fluorescent Microscopy Imaging

(2009) Nicholas Hamilton   TRAFFIC

Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra

(2008) Yu He et al.   NATURE

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY