Remote Actuation of Apoptosis in Liver Cancer Cells via Magneto-Mechanical Modulation of Iron Oxide Nanoparticles

Targeting the mTOR Signaling Pathway Utilizing Nanoparticles: A Critical Overview

(2019) Mariia Lunova et al.   Cancers

Light-induced modulation of the mitochondrial respiratory chain activity: possibilities and limitations

(2019) Mariia Lunova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lysosomal membrane permeabilization as a cell death mechanism in cancer cells

(2018) Ana Serrano-Puebla et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Repurposing cationic amphiphilic drugs as adjuvants to induce lysosomal siRNA escape in nanogel transfected cells

(2018) Freya Joris et al.   JOURNAL OF CONTROLLED RELEASE

Progress and challenges towards targeted delivery of cancer therapeutics

(2018) Daniel Rosenblum et al.   Nature Communications

Manipulating the mitochondria activity in human hepatic cell line Huh7 by low-power laser irradiation

(2018) Anna Lynnyk et al.   Biomedical Optics Express

Uptake, distribution, clearance, and toxicity of iron oxide nanoparticles with different sizes and coatings

(2018) Qiyi Feng et al.   Scientific Reports

Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning

(2018) Sigrid A. Langhans   Frontiers in Pharmacology

Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization

(2018) Susan Hua et al.   Frontiers in Pharmacology

Lysosomal membrane permeabilization and cell death

(2018) Fengjuan Wang et al.   TRAFFIC

From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

(2017) Avi Ashkenazi et al.   NATURE REVIEWS DRUG DISCOVERY

The therapeutic potential of three-dimensional multipotent mesenchymal stromal cell spheroids

(2017) Yuriy Petrenko et al.   Stem Cell Research & Therapy

Multifaceted Biomedical Applications of Functional Graphene Nanomaterials to Coated Substrates, Patterned Arrays and Hybrid Scaffolds

(2017) Yong Shin et al.   Nanomaterials

Chemically different non-thermal plasmas target distinct cell death pathways

(2017) Oleg Lunov et al.   Scientific Reports

Magneto-actuated cell apoptosis by biaxial pulsed magnetic field

(2017) De Wei Wong et al.   Scientific Reports

Nanoparticle core stability and surface functionalization drive the mTOR signaling pathway in hepatocellular cell lines

(2017) Mariia Lunova et al.   Scientific Reports

The interplay between biological and physical scenarios of bacterial death induced by non-thermal plasma

(2016) Oleg Lunov et al.   BIOMATERIALS

Mechanical Criterion for the Rupture of a Cell Membrane under Compression

(2016) David Gonzalez-Rodriguez et al.   BIOPHYSICAL JOURNAL

Mechanisms and functions of lysosome positioning

(2016) Jing Pu et al.   JOURNAL OF CELL SCIENCE

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

(2016) Yi-Nan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Applications of magnetic nanoparticles in biomedicine: the story so far

(2016) Quentin Pankhurst et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Non-Temperature Induced Effects of Magnetized Iron Oxide Nanoparticles in Alternating Magnetic Field in Cancer Cells

(2016) Sudath Hapuarachchige et al.   PLoS One

Nanomechanical mechanism for lipid bilayer damage induced by carbon nanotubes confined in intracellular vesicles

(2016) Wenpeng Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monodisperse magnetite nanoparticles with nearly ideal saturation magnetization

(2016) Scott J. Kemp et al.   RSC Advances

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Remote Actuation of Magnetic Nanoparticles For Cancer Cell Selective Treatment Through Cytoskeletal Disruption

(2016) Alyssa M. Master et al.   Scientific Reports

How a High-Gradient Magnetic Field Could Affect Cell Life

(2016) Vitalii Zablotskii et al.   Scientific Reports

Clearance Pathways and Tumor Targeting of Imaging Nanoparticles

(2015) Mengxiao Yu et al.   ACS Nano

Targeting the lysosome in cancer

(2015) Shengfu Piao et al.   Annals of the New York Academy of Sciences

Lysosomal proteins in cell death and autophagy

(2015) Michaela Mrschtik et al.   FEBS Journal

Towards nanomedicines of the future: Remote magneto-mechanical actuation of nanomedicines by alternating magnetic fields

(2015) Yuri I. Golovin et al.   JOURNAL OF CONTROLLED RELEASE

Triggering the apoptosis of targeted human renal cancer cells by the vibration of anisotropic magnetic particles attached to the cell membrane

(2015) Selma Leulmi et al.   Nanoscale

An effective strategy of magnetic stem cell delivery for spinal cord injury therapy

(2015) Dmitry Tukmachev et al.   Nanoscale

Dynamic Magnetic Fields Remote-Control Apoptosis via Nanoparticle Rotation

(2014) Enming Zhang et al.   ACS Nano

Three-dimensional in vitro tumor models for cancer research and drug evaluation

(2014) Xian Xu et al.   BIOTECHNOLOGY ADVANCES

Evaluation of acridine orange, LysoTracker Red, and quinacrine as fluorescent probes for long-term tracking of acidic vesicles

(2014) Agnieszka Pierzyńska-Mach et al.   CYTOMETRY PART A

HCC cells with high levels of Bcl-2 are resistant to ABT-737 via activation of the ROS–JNK–autophagy pathway

(2014) Zhenhong Ni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak

(2014) L. M. Lindqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell death induced by ozone and various non-thermal plasmas: therapeutic perspectives and limitations

(2014) Oleg Lunov et al.   Scientific Reports

Lysosomal Membrane Permeabilization by Targeted Magnetic Nanoparticles in Alternating Magnetic Fields

(2013) Maribella Domenech et al.   ACS Nano

Transformation-Associated Changes in Sphingolipid Metabolism Sensitize Cells to Lysosomal Cell Death Induced by Inhibitors of Acid Sphingomyelinase

(2013) Nikolaj H.T. Petersen et al.   CANCER CELL

Magnetic fluid hyperthermia: Advances, challenges, and opportunity

(2013) Bettina Kozissnik et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosomal Membrane Proteins and Their Central Role in Physiology

(2013) Michael Schwake et al.   TRAFFIC

Biological applications of magnetic nanoparticles

(2012) Miriam Colombo et al.   CHEMICAL SOCIETY REVIEWS

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Magnetic nanoparticle–mediated massively parallel mechanical modulation of single-cell behavior

(2012) Peter Tseng et al.   NATURE METHODS

DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway

(2012) M A Kang et al.   Cell Death & Disease

Nanomechanics of magnetically driven cellular endocytosis

(2011) V. Zablotskii et al.   APPLIED PHYSICS LETTERS

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Comparative Analysis of Viscosity of Complex Liquids and Cytoplasm of Mammalian Cells at the Nanoscale

(2011) Tomasz Kalwarczyk et al.   NANO LETTERS

The dose makes the poison

(2011)   Nature Nanotechnology

Noninvasive cell-tracking methods

(2011) Moritz F. Kircher et al.   Nature Reviews Clinical Oncology

Nanoparticle Induced Cell Magneto-Rotation: Monitoring Morphology, Stress and Drug Sensitivity of a Suspended Single Cancer Cell

(2011) Remy Elbez et al.   PLoS One

Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples

(2011) J. B. Haun et al.   Science Translational Medicine

A Simple Hanging Drop Cell Culture Protocol for Generation of 3D Spheroids

(2011) Ramsey Foty   Jove-Journal of Visualized Experiments

Regulation of apoptosis-associated lysosomal membrane permeabilization

(2010) Ann-Charlotte Johansson et al.   APOPTOSIS

Lysosomal degradation of the carboxydextran shell of coated superparamagnetic iron oxide nanoparticles and the fate of professional phagocytes

(2010) Oleg Lunov et al.   BIOMATERIALS

The effect of carboxydextran-coated superparamagnetic iron oxide nanoparticles on c-Jun N-terminal kinase-mediated apoptosis in human macrophages

(2010) Oleg Lunov et al.   BIOMATERIALS

Modeling receptor-mediated endocytosis of polymer-functionalized iron oxide nanoparticles by human macrophages

(2010) Oleg Lunov et al.   BIOMATERIALS

Multifunctional superparamagnetic nanocarriers with folate-mediated and pH-responsive targeting properties for anticancer drug delivery

(2010) Miao Guo et al.   BIOMATERIALS

Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

(2010) L. Guo et al.   DRUG METABOLISM AND DISPOSITION

Molecular dynamics simulations of rupture in lipid bilayers

(2010) Michael D Tomasini et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

(2010) Thomas Kirkegaard et al.   NATURE

Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology

(2009) G. Oberdörster   JOURNAL OF INTERNAL MEDICINE

Biofunctionalized magnetic-vortex microdiscs for targeted cancer-cell destruction

(2009) Dong-Hyun Kim et al.   NATURE MATERIALS

Matrix-insensitive protein assays push the limits of biosensors in medicine

(2009) Richard S Gaster et al.   NATURE MEDICINE

Quantification and its Applications in Fluorescent Microscopy Imaging

(2009) Nicholas Hamilton   TRAFFIC

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Remote control of cellular behaviour with magnetic nanoparticles

(2008) Jon Dobson   Nature Nanotechnology

BCL-2 family antagonists for cancer therapy

(2008) Guillaume Lessene et al.   NATURE REVIEWS DRUG DISCOVERY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE