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Title
Disease modelling using human iPSCs
Authors
Keywords
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Journal
HUMAN MOLECULAR GENETICS
Volume 25, Issue R2, Pages R173-R181
Publisher
Oxford University Press (OUP)
Online
2016-08-05
DOI
10.1093/hmg/ddw209
References
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Note: Only part of the references are listed.- GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient induced pluripotent stem cell model
- (2016) Himanshu K. Mishra et al. ANNALS OF NEUROLOGY
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- (2016) Kiyohito Murai et al. Nature Communications
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- (2016) Chung-Wah Siu et al. Aging-US
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- (2015) Aaron Topol et al. BIOLOGICAL PSYCHIATRY
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- (2015) Jessica Mariani et al. CELL
- A perspective on stem cell modeling of amyotrophic lateral sclerosis
- (2015) A Sophie de Boer et al. CELL CYCLE
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- (2015) B. Lin et al. Disease Models & Mechanisms
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- (2015) Karim Si-Tayeb et al. Disease Models & Mechanisms
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- (2015) Saranya P. Wyles et al. HUMAN MOLECULAR GENETICS
- Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities
- (2015) J M Madison et al. MOLECULAR PSYCHIATRY
- Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
- (2015) Jerome Mertens et al. NATURE
- Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
- (2015) J. T. Hinson et al. SCIENCE
- Increased abundance of translation machinery in stem cell–derived neural progenitor cells from four schizophrenia patients
- (2015) A Topol et al. Translational Psychiatry
- Modeling the Early Phenotype at the Neuromuscular Junction of Spinal Muscular Atrophy Using Patient-Derived iPSCs
- (2015) Michiko Yoshida et al. Stem Cell Reports
- Disease modeling and lentiviral gene transfer in patient-specific induced pluripotent stem cells from late-onset Pompe disease patient
- (2015) Yohei Sato et al. Molecular Therapy-Methods & Clinical Development
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- (2014) Tetsuhiko Yasuno et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2014) Lu Han et al. CARDIOVASCULAR RESEARCH
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- (2014) Hong Chen et al. Cell Stem Cell
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- (2014) Peng-Peng Zhu et al. HUMAN MOLECULAR GENETICS
- Pompe Disease Results in a Golgi-based Glycosylation Deficit in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes
- (2014) Kunil K. Raval et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-α-glucosidase in Pompe's iPSCs
- (2014) Takashi Higuchi et al. MOLECULAR GENETICS AND METABOLISM
- Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons
- (2014) K Griesi-Oliveira et al. MOLECULAR PSYCHIATRY
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- (2014) K Brennand et al. MOLECULAR PSYCHIATRY
- The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome
- (2014) Yonatan Stelzer et al. NATURE GENETICS
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- (2014) Gang Wang et al. NATURE MEDICINE
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- (2014) Matthew E. Doers et al. STEM CELLS AND DEVELOPMENT
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- (2014) Mandana Arbab et al. TRENDS IN NEUROSCIENCES
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- (2014) Brian J. Wainger et al. Cell Reports
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- (2014) Yuan Tian et al. Genome Medicine
- Endothelin‐1 Induces Myofibrillar Disarray and Contractile Vector Variability in Hypertrophic Cardiomyopathy–Induced Pluripotent Stem Cell–Derived Cardiomyocytes
- (2014) Atsushi Tanaka et al. Journal of the American Heart Association
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- (2014) Noelle D Germain et al. Molecular Autism
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- (2014) Vivian Hook et al. Stem Cell Reports
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- (2013) Takayuki Kondo et al. Cell Stem Cell
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- (2013) Milena Bellin et al. EMBO JOURNAL
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- (2013) Kristen Martins-Taylor et al. HUMAN MOLECULAR GENETICS
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- (2012) Faranak Fattahi et al. MOLECULAR BIOTECHNOLOGY
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- (2012) N Farra et al. MOLECULAR PSYCHIATRY
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- (2012) Mason A. Israel et al. NATURE
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- (2012) Sara Ricciardi et al. NATURE CELL BIOLOGY
- Generation of induced pluripotent stem cells from a small amount of human peripheral blood using a combination of activated T cells and Sendai virus
- (2012) Tomohisa Seki et al. Nature Protocols
- The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity
- (2012) Stefano Camnasio et al. NEUROBIOLOGY OF DISEASE
- Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Reveals Early and Delayed Afterdepolarizations
- (2012) Kirsi Kujala et al. PLoS One
- Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
- (2012) B. Bilican et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy
- (2012) N. Sun et al. Science Translational Medicine
- Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells
- (2012) Houbo Jiang et al. Nature Communications
- Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells
- (2012) Tarja A Juopperi et al. Molecular Brain
- Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
- (2012) Yoichi Imaizumi et al. Molecular Brain
- X-Chromosome Inactivation in Rett Syndrome Human Induced Pluripotent Stem Cells
- (2012) Aaron Y. L. Cheung et al. Frontiers in Psychiatry
- Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
- (2011) Frank Soldner et al. CELL
- LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
- (2011) Ha Nam Nguyen et al. Cell Stem Cell
- Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
- (2011) A. L. Lahti et al. Disease Models & Mechanisms
- Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia
- (2011) Christian B. Jung et al. EMBO Molecular Medicine
- Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation
- (2011) Elena Matsa et al. EUROPEAN HEART JOURNAL
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- (2011) Takuya Yagi et al. HUMAN MOLECULAR GENETICS
- Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients
- (2011) Miguel Mitne-Neto et al. HUMAN MOLECULAR GENETICS
- Development of Patient-Specific Neurons in Schizophrenia Using Induced Pluripotent Stem Cells
- (2011) Erika Pedrosa et al. JOURNAL OF NEUROGENETICS
- Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells
- (2011) P. Seibler et al. JOURNAL OF NEUROSCIENCE
- Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
- (2011) Masayuki Yazawa et al. NATURE
- Modelling the long QT syndrome with induced pluripotent stem cells
- (2011) Ilanit Itzhaki et al. NATURE
- Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells
- (2011) Kitai Kim et al. NATURE BIOTECHNOLOGY
- Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
- (2011) Sergiu P Paşca et al. NATURE MEDICINE
- Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome
- (2011) Steven D. Sheridan et al. PLoS One
- A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
- (2010) Maria C.N. Marchetto et al. CELL
- Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells
- (2010) Matthew G. Guenther et al. Cell Stem Cell
- Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells
- (2010) Judith Staerk et al. Cell Stem Cell
- Induced pluripotency: history, mechanisms, and applications
- (2010) M. Stadtfeld et al. GENES & DEVELOPMENT
- Induced Pluripotent Stem Cells Can Be Used to Model the Genomic Imprinting Disorder Prader-Willi Syndrome
- (2010) Jiayin Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
- (2010) Xonia Carvajal-Vergara et al. NATURE
- Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes
- (2010) Stormy J. Chamberlain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generation of Transgene-Free Lung Disease-Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette
- (2010) Aba Somers et al. STEM CELLS
- Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins
- (2009) Dohoon Kim et al. Cell Stem Cell
- Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins
- (2009) Hongyan Zhou et al. Cell Stem Cell
- Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
- (2009) Gabsang Lee et al. NATURE
- Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
- (2009) J. Yu et al. SCIENCE
- iPS Cells Reprogrammed From Human Mesenchymal-Like Stem/Progenitor Cells of Dental Tissue Origin
- (2009) Xing Yan et al. STEM CELLS AND DEVELOPMENT
- Disease-Specific Induced Pluripotent Stem Cells
- (2008) In-Hyun Park et al. CELL
- Induced pluripotent stem cells from a spinal muscular atrophy patient
- (2008) Allison D. Ebert et al. NATURE
- Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
- (2008) Jeong Beom Kim et al. NATURE
- Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
- (2008) Trond Aasen et al. NATURE BIOTECHNOLOGY
- Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
- (2008) J. T. Dimos et al. SCIENCE
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