Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A
Authors
Keywords
-
Journal
HUMAN MOLECULAR GENETICS
Volume 23, Issue 21, Pages 5638-5648
Publisher
Oxford University Press (OUP)
Online
2014-06-08
DOI
10.1093/hmg/ddu280
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Exome Sequencing Links Corticospinal Motor Neuron Disease to Common Neurodegenerative Disorders
- (2014) G. Novarino et al. SCIENCE
- Structural basis for conformational switching and GTP loading of the large G protein atlastin
- (2013) Laura J Byrnes et al. EMBO JOURNAL
- ROOT HAIR DEFECTIVE3 Family of Dynamin-Like GTPases Mediates Homotypic Endoplasmic Reticulum Fusion and Is Essential for Arabidopsis Development
- (2013) M. Zhang et al. PLANT PHYSIOLOGY
- Loss of Spastin Function Results in Disease-Specific Axonal Defects in Human Pluripotent Stem Cell-Based Models of Hereditary Spastic Paraplegia
- (2013) Kyle R. Denton et al. STEM CELLS
- Motile Axonal Mitochondria Contribute to the Variability of Presynaptic Strength
- (2013) Tao Sun et al. Cell Reports
- A Conserved Role for Atlastin GTPases in Regulating Lipid Droplet Size
- (2013) Robin W. Klemm et al. Cell Reports
- Cellular Pathways of Hereditary Spastic Paraplegia
- (2012) Craig Blackstone Annual Review of Neuroscience
- Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy
- (2012) Zhi-Bo Wang et al. CELL RESEARCH
- A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
- (2012) G. Abrahamsen et al. Disease Models & Mechanisms
- Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice
- (2012) C. Fassier et al. Disease Models & Mechanisms
- The dynamin-like GTPase Sey1p mediates homotypic ER fusion inS. cerevisiae
- (2012) Kamran Anwar et al. JOURNAL OF CELL BIOLOGY
- ATL1 and REEP1 mutations in hereditary and sporadic upper motor neuron syndromes
- (2012) S. T. Bot et al. JOURNAL OF NEUROLOGY
- Hereditary spastic paraplegias with autosomal dominant, recessive, X-linked, or maternal trait of inheritance
- (2012) Josef Finsterer et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Hereditary spastic paraplegia-causing mutations in atlastin-1 interfere with BMPRII trafficking
- (2012) Jiali Zhao et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Genetics of Hereditary Spastic Paraplegias
- (2012) Rebecca Schüle et al. SEMINARS IN NEUROLOGY
- Increased Axonal Mitochondrial Mobility Does Not Slow Amyotrophic Lateral Sclerosis (ALS)-like Disease in Mutant SOD1 Mice
- (2011) Yi-Bing Zhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Arabidopsis RHD3 mediates the generation of the tubular ER network and is required for Golgi distribution and motility in plant cells
- (2011) J. Chen et al. JOURNAL OF CELL SCIENCE
- A more efficient method to generate integration-free human iPS cells
- (2011) Keisuke Okita et al. NATURE METHODS
- Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A
- (2011) L. J. Byrnes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted High-Throughput Sequencing Identifies Mutations in atlastin-1 as a Cause of Hereditary Sensory Neuropathy Type I
- (2010) Christian Guelly et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Further assembly required: construction and dynamics of the endoplasmic reticulum network
- (2010) Seong H Park et al. EMBO REPORTS
- Hereditary spastic paraplegia proteins REEP1, spastin, and atlastin-1 coordinate microtubule interactions with the tubular ER network
- (2010) Seong H. Park et al. JOURNAL OF CLINICAL INVESTIGATION
- Zebrafish atlastin controls motility and spinal motor axon architecture via inhibition of the BMP pathway
- (2010) Coralie Fassier et al. NATURE NEUROSCIENCE
- Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease
- (2010) Nobutaka Hirokawa et al. NEURON
- Specification of Region-Specific Neurons Including Forebrain Glutamatergic Neurons from Human Induced Pluripotent Stem Cells
- (2010) Hui Zeng et al. PLoS One
- A Class of Dynamin-like GTPases Involved in the Generation of the Tubular ER Network
- (2009) Junjie Hu et al. CELL
- Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells
- (2009) X.-J. Li et al. DEVELOPMENT
- Drosophila Atlastin regulates the stability of muscle microtubules and is required for synapse development
- (2009) Mihye Lee et al. DEVELOPMENTAL BIOLOGY
- Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients
- (2009) Paul R. Kasher et al. JOURNAL OF NEUROCHEMISTRY
- Axonal Transport Defects in Neurodegenerative Diseases
- (2009) G. A. Morfini et al. JOURNAL OF NEUROSCIENCE
- Homotypic fusion of ER membranes requires the dynamin-like GTPase Atlastin
- (2009) Genny Orso et al. NATURE
- Effect of spastic paraplegia mutations in KIF5A kinesin on transport activity
- (2008) Bettina Ebbing et al. HUMAN MOLECULAR GENETICS
- Atlastin GTPases are required for Golgi apparatus and ER morphogenesis
- (2008) Neggy Rismanchi et al. HUMAN MOLECULAR GENETICS
- Quantitative and Functional Analyses of Spastin in the Nervous System: Implications for Hereditary Spastic Paraplegia
- (2008) J. M. Solowska et al. JOURNAL OF NEUROSCIENCE
- Membrane Proteins of the Endoplasmic Reticulum Induce High-Curvature Tubules
- (2008) J. Hu et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search