Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

(2010) Alessandra Moretti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2009) Jianhua Zhang et al.   CIRCULATION RESEARCH

Roscovitine Binds to Novel L-channel (CaV1.2) Sites That Separately Affect Activation and Inactivation

(2009) Viktor Yarotskyy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt3a-Induced Mesoderm Formation and Cardiomyogenesis in Human Embryonic Stem Cells

(2009) Thanh H. Tran et al.   STEM CELLS

Proarrhythmic Defects in Timothy Syndrome Require Calmodulin Kinase II

(2008) William H. Thiel et al.   CIRCULATION

The Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation

(2008) Viktor Yarotskyy et al.   JOURNAL OF PHYSIOLOGY-LONDON

Long-QT Syndrome

(2008) Dan M. Roden   NEW ENGLAND JOURNAL OF MEDICINE

The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels

(2008) C. F. Barrett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells

(2008) T. Aoi et al.   SCIENCE

Roscovitine, a cyclin-dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L-type (Ca(V)1.2) calcium channels

(2007) V Yarotskyy et al.   BRITISH JOURNAL OF PHARMACOLOGY