Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells

Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease

(2011) Yong-Hee Rhee et al.   JOURNAL OF CLINICAL INVESTIGATION

A functionally characterized test set of human induced pluripotent stem cells

(2011) Gabriella L Boulting et al.   NATURE BIOTECHNOLOGY

In vivo assessment of brain monoamine systems in parkin gene carriers: A PET study

(2010) Nicola Pavese et al.   EXPERIMENTAL NEUROLOGY

Parkin degrades estrogen-related receptors to limit the expression of monoamine oxidases

(2010) Y. Ren et al.   HUMAN MOLECULAR GENETICS

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

(2010) Karen Nuytemans et al.   HUMAN MUTATION

Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory

(2010) E Y Yuen et al.   MOLECULAR PSYCHIATRY

The role of parkin in familial and sporadic Parkinson's disease

(2010) Ted M. Dawson et al.   MOVEMENT DISORDERS

Genetic Analysis of Pathways to Parkinson Disease

(2010) John Hardy   NEURON

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

(2010) B.-Y. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mobilization of Calcium from Intracellular Stores Facilitates Somatodendritic Dopamine Release

(2009) J. C. Patel et al.   JOURNAL OF NEUROSCIENCE

A Multitracer Dopaminergic PET Study of Young-Onset Parkinsonian Patients With and Without Parkin Gene Mutations

(2009) M.-J. Ribeiro et al.   JOURNAL OF NUCLEAR MEDICINE

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease

(2009) Cristine Alves da Costa et al.   NATURE CELL BIOLOGY

A Double-Blind, Delayed-Start Trial of Rasagiline in Parkinson's Disease

(2009) C. Warren Olanow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Homeostatic mechanisms in dopamine synthesis and release: a mathematical model

(2009) Janet A Best et al.   Theoretical Biology and Medical Modelling

A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells

(2008) Nimet Maherali et al.   Cell Stem Cell

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY