GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient induced pluripotent stem cell model

Clinical and genetic heterogeneity in hereditary spastic paraplegias: From SPG1 to SPG72 and still counting

(2015) S. Klebe et al.   REVUE NEUROLOGIQUE

Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes

(2014) Timothy J. Edwards et al.   BRAIN

Hox Proteins Mediate Developmental and Environmental Control of Autophagy

(2014) Agnes Banreti et al.   DEVELOPMENTAL CELL

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

(2014) S. Havlicek et al.   HUMAN MOLECULAR GENETICS

Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia

(2014) Francesc Pérez-Brangulí et al.   HUMAN MOLECULAR GENETICS

Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation

(2014) Jaerak Chang et al.   JOURNAL OF CLINICAL INVESTIGATION

Lysosomal abnormalities in hereditary spastic paraplegia types SPG15 and SPG11

(2014) Benoît Renvoisé et al.   Annals of Clinical and Translational Neurology

mTOR-dependent proliferation defect in human ES-derived neural stem cells affected by myotonic dystrophy type 1

(2013) J. A. Denis et al.   JOURNAL OF CELL SCIENCE

Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression

(2013) C. Novorol et al.   Open Biology

Spg20−/− mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signaling

(2012) Benoît Renvoisé et al.   HUMAN MOLECULAR GENETICS

Signaling defects in iPSC-derived fragile X premutation neurons

(2012) Jing Liu et al.   HUMAN MOLECULAR GENETICS

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

(2011) Sergiu P Paşca et al.   NATURE MEDICINE

Erratum: Hereditary spastic paraplegias: membrane traffic and the motor pathway

(2011) Craig Blackstone et al.   NATURE REVIEWS NEUROSCIENCE

Progranulin enhances neural progenitor cell proliferation through glycogen synthase kinase 3β phosphorylation

(2011) T. Nedachi et al.   NEUROSCIENCE

Analysis of the Transcriptional Program of Developing Induced Regulatory T Cells

(2011) Iryna Prots et al.   PLoS One

Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

(2011) Steven D. Sheridan et al.   PLoS One

SPATACSIN mutations cause autosomal recessive juvenile amyotrophic lateral sclerosis

(2010) A. Orlacchio et al.   BRAIN

The Development of the Corpus Callosum in the Healthy Human Brain

(2010) E. Luders et al.   JOURNAL OF NEUROSCIENCE

PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

(2010) Antonia P. Sagona et al.   NATURE CELL BIOLOGY

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

GSK-3 is a master regulator of neural progenitor homeostasis

(2009) Woo-Yang Kim et al.   NATURE NEUROSCIENCE

Phospholipase Cδ1 regulates cell proliferation and cell-cycle progression from G1- to S-phase by control of cyclin E–CDK2 activity

(2008) Katherine A. Kaproth-Joslin et al.   BIOCHEMICAL JOURNAL

Wnt Signaling Inhibits Forkhead Box O3a-induced Transcription and Apoptosis through Up-regulation of Serum- and Glucocorticoid-inducible Kinase 1

(2008) Manuel Dehner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a heterozygous genomic deletion in the spatacsin gene in SPG11 patients using high-resolution comparative genomic hybridization

(2008) Peter Bauer et al.   NEUROGENETICS

Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion

(2008) James W. Connell et al.   TRAFFIC