Solvent- and halide-free synthesis of pyridine-2-yl substituted ureas through facile C–H functionalization of pyridine N-oxides

Metal-involving generation of aminoheterocycles from N-substituted cyanamides: Toward sustainable chemistry (a Minireview)

(2017) Dmitrii S. Bolotin et al.   INORGANICA CHIMICA ACTA

A lipase–glucose oxidase system for the efficient oxidation of N-heteroaromatic compounds and tertiary amines

(2016) Fengjuan Yang et al.   GREEN CHEMISTRY

N-Butylpyrrolidinone as a dipolar aprotic solvent for organic synthesis

(2016) James Sherwood et al.   GREEN CHEMISTRY

Green chemistry and resource efficiency: towards a green economy

(2016) Roger A. Sheldon   GREEN CHEMISTRY

Discovery of 1-(1H-Pyrazolo[4,3-c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers

(2016) Jongwon Lim et al.   JOURNAL OF MEDICINAL CHEMISTRY

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

(2016) Michael E Pacold et al.   Nature Chemical Biology

β-Strand Mimetic Foldamers Rigidified through Dipolar Repulsion

(2015) Elizabeth A. German et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and synthesis of novel 1,2,3-triazole–pyrimidine–urea hybrids as potential anticancer agents

(2015) Li-Ying Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Multitargeting strategy using lenvatinib and golvatinib: Maximizing anti-angiogenesis activity in a preclinical cancer model

(2015) Youya Nakazawa et al.   CANCER SCIENCE

Computer-Guided Design, Synthesis, and Biological Evaluation of Quinoxalinebisarylureas as FLT3 Inhibitors

(2015) Stefan Göring et al.   ChemMedChem

Advances in tetrahydropyrido[1,2- a ]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors

(2015) Rajâa Boulahjar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Metal-mediated cyanamide–hydroxyguanidine coupling

(2015) Marina Ya. Demakova et al.   INORGANICA CHIMICA ACTA

Bis-aryl Urea Derivatives as Potent and Selective LIM Kinase (Limk) Inhibitors

(2015) Yan Yin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Zinc(ii)-mediated generation of 5-amino substituted 2,3-dihydro-1,2,4-oxadiazoles and their further ZnII-catalyzed and O2-involving transformations

(2015) Andrey S. Smirnov et al.   NEW JOURNAL OF CHEMISTRY

Ruthenium-Catalyzed Urea Synthesis Using Methanol as the C1 Source

(2015) Seung Hyo Kim et al.   ORGANIC LETTERS

Facile Gold-Catalyzed Heterocyclization of Terminal Alkynes and Cyanamides Leading to Substituted 2-Amino-1,3-Oxazoles

(2015) Valentin A. Rassadin et al.   ORGANIC LETTERS

Gold-Catalyzed 1,2-Oxoarylations of Nitriles with Pyridine-Derived Oxides

(2014) Somnath Narayan Karad et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery libraries targeting the major enzyme classes: The serine hydrolases

(2014) Katerina Otrubova et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Supramolecular pyridyl urea gels as soft matter with antibacterial properties against MRSA and/or E. coli

(2014) Komala Pandurangan et al.   CHEMICAL COMMUNICATIONS

Sulfur–silicon bond activation catalysed by Cl/Br ions: waste-free synthesis of unsymmetrical thioethers by replacing fluoride catalysis and fluorinated substrates in SNAr reactions

(2014) Xiaojuan Jia et al.   GREEN CHEMISTRY

Design, Synthesis, and Evaluation of Nonretinoid Retinol Binding Protein 4 Antagonists for the Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease

(2014) Christopher L. Cioffi et al.   JOURNAL OF MEDICINAL CHEMISTRY

BippyPhos: A Single Ligand With Unprecedented Scope in the Buchwald-Hartwig Amination of (Hetero)aryl Chlorides

(2013) Sarah M. Crawford et al.   CHEMISTRY-A EUROPEAN JOURNAL

Coordination chemistry of dialkylcyanamides: Binding properties, synthesis of metal complexes, and ligand reactivity

(2013) Nadezhda A. Bokach et al.   COORDINATION CHEMISTRY REVIEWS

Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents

(2013) Gregory S. Basarab et al.   JOURNAL OF MEDICINAL CHEMISTRY

Association of N-(Pyridin-2-yl),N′-substituted Ureas with 2-Amino-1,8-naphthyridines and Benzoates: NMR and Quantum Chemical Studies of the Substituent Effect on Complexation

(2013) Borys Ośmiałowski et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Unsymmetrical 2-Pyridyl Ureas via Selenium-Catalyzed Oxi­dative Carbonylation of 2-Aminopyridine with Aromatic Amines

(2013) Xiaopeng Zhang et al.   SYNTHESIS-STUTTGART

Copper-catalysed amidation of 2-chloro-pyridines

(2013) Lionel Nicolas et al.   RSC Advances

Equipping metallo-supramolecular macrocycles with functional groups: assemblies of pyridine-substituted urea ligands

(2012) Ralf W. Troff et al.   DALTON TRANSACTIONS

Copper-catalyzed N-arylation of sulfonamides with aryl bromides under mild conditions

(2011) Xiang Wang et al.   TETRAHEDRON LETTERS

Radical Synthesis of Guanidines fromN-Acyl Cyanamides

(2010) Marie-Hélène Larraufie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Phenyl-N′-[4-(5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as novel inhibitors of VEGFR and FGFR kinases

(2010) Yuya Oguro et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: Novel VEGFR2 kinase inhibitors binding to inactive kinase conformation

(2010) Yuya Oguro et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of urea derivatives from amines and CO2 in the absence of catalyst and solvent

(2010) Chaoyong Wu et al.   GREEN CHEMISTRY

Palladium-Catalyzed Chemoselective Monoarylation of Hydrazides for the Synthesis of [1,2,4]Triazolo[4,3-a]pyridines

(2010) Andreas Reichelt et al.   ORGANIC LETTERS

Evaluation of Diarylureas for Activity Against Plasmodium falciparum

(2010) Yiqun Zhang et al.   ACS Medicinal Chemistry Letters

A General Method for the Synthesis of Unsymmetrically Substituted Ureas via Palladium-Catalyzed Amidation

(2009) Brian J. Kotecki et al.   ORGANIC LETTERS

Lanthanide-Induced Diinsertion of Isocyanates into the N−H Bond: Synthesis, Structure, and Reactivity of Organolanthanides Containing Diureido Ligands

(2009) Yan Sun et al.   ORGANOMETALLICS

Rapid synthesis of imidazo[4,5-b]pyridine containing polycyclics by means of palladium-catalyzed amidation of 2-chloro-3-nitropyridine

(2009) Christophe Salomé et al.   TETRAHEDRON LETTERS

Gradual Transition from NH···Pyridyl Hydrogen Bonding to the NH···O Tape Synthon in Pyridyl Ureas

(2008) Peter Byrne et al.   CRYSTAL GROWTH & DESIGN

Solvent-free synthesis of substituted ureas from CO2 and amines with a functional ionic liquid as the catalyst

(2008) Tao Jiang et al.   GREEN CHEMISTRY

Toxic Reactivity of Wheat (Triticum aestivum) Plants to Herbicide Isoproturon

(2008) Xiao Le Yin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Preparation of the Maleic Anhydride Nucleus from Dichloro γ-Lactams: Focus on the Role of the N-Substituent in the Functional Rearrangement and in the Hydrolytic Steps

(2008) Franco Ghelfi et al.   SYNTHESIS-STUTTGART