Journal
SYNTHESIS-STUTTGART
Volume 45, Issue 10, Pages 1357-1363Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1338413
Keywords
carbonylation; selenium; carbon monoxide; 2-pyridyl ureas; 2-aminopyridine
Categories
Funding
- Program for Changjiang Scholars and Innovative Research Team in University [IRT1061]
- Henan Normal University [2009PL06]
- Education Department of Henan Province, China [2009B150013]
Ask authors/readers for more resources
A simple, one-pot, phosgene-free approach to a series of unsymmetrical 2-pyridyl ureas starting from 2-aminopyridine and various aromatic amines is reported for the first time. The procedure employs inexpensive selenium as the catalyst, and carbon monoxide (instead of phosgene) as the carbonyl reagent. The products are obtained in moderate to good yields via selenium-catalyzed oxidative cross-carbonylation of the substrate amines in the presence of oxygen. The selenium functions as a phase-transfer catalyst and can be recovered easily and reused without any significant degradation of its catalytic activity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available