Immunotherapy in endometrial cancer: rationale, practice and perspectives
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Title
Immunotherapy in endometrial cancer: rationale, practice and perspectives
Authors
Keywords
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Journal
Biomarker Research
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-06-16
DOI
10.1186/s40364-021-00301-z
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Note: Only part of the references are listed.- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- ARID1A deficiency and immune checkpoint blockade therapy: From mechanisms to clinical application
- (2020) Guangyuan Hu et al. CANCER LETTERS
- Endocrine therapy in endometrial cancer: An old dog with new tricks
- (2019) Katarzyna J. Jerzak et al. GYNECOLOGIC ONCOLOGY
- Tumor mutational load predicts survival after immunotherapy across multiple cancer types
- (2019) Robert M. Samstein et al. NATURE GENETICS
- Delivery technologies for cancer immunotherapy
- (2019) Rachel S. Riley et al. NATURE REVIEWS DRUG DISCOVERY
- TIM-3 in endometrial carcinomas: an immunotherapeutic target expressed by mismatch repair-deficient and intact cancers
- (2019) Margaret Moore et al. MODERN PATHOLOGY
- Lenvatinib plus pembrolizumab in patients with advanced endometrial cancer: an interim analysis of a multicentre, open-label, single-arm, phase 2 trial
- (2019) Vicky Makker et al. LANCET ONCOLOGY
- Sex hormones and anticancer immunity
- (2019) Berna C. Özdemir et al. CLINICAL CANCER RESEARCH
- Phase 1 Immunotherapy Trial with Two Chimeric HER-2 B-Cell Peptide Vaccines emulsified in Montanide ISA 720VG and nor-MDP Adjuvant in Advanced Solid Tumors
- (2019) Tanios Bekaii-Saab et al. CLINICAL CANCER RESEARCH
- Fratricide-resistant CD1a-specific CAR T-cells for the treatment of cortical T-cell acute lymphoblastic leukemia
- (2019) Diego Sánchez-Martínez et al. BLOOD
- Tumor mutational burden and other predictive immunotherapy markers in histiocytic neoplasms
- (2019) Gaurav Goyal et al. BLOOD
- ESMO recommendations on microsatellite instability testing for immunotherapy in cancer, and its relationship with PD-1/PD-L1 expression and tumour mutational burden: a systematic review-based approach
- (2019) C Luchini et al. ANNALS OF ONCOLOGY
- Expression analysis and significance of PD-1, LAG-3 and TIM-3 in human non-small cell lung cancer using spatially-resolved and multiparametric single-cell analysis.
- (2019) Ila J Datar et al. CLINICAL CANCER RESEARCH
- Hysterectomy-Corrected Uterine Corpus Cancer Incidence Trends and Differences in Relative Survival Reveal Racial Disparities and Rising Rates of Nonendometrioid Cancers
- (2019) Megan A. Clarke et al. JOURNAL OF CLINICAL ONCOLOGY
- A phase II trial of durvalumab with or without tremelimumab in patients with persistent or recurrent endometrial carcinoma and endometrial carcinosarcoma.
- (2019) Maria M Rubinstein et al. JOURNAL OF CLINICAL ONCOLOGY
- Analysis of DNA Damage Response Gene Alterations and Tumor Mutational Burden Across 17,486 Tubular Gastrointestinal Carcinomas: Implications for Therapy
- (2019) Aparna R. Parikh et al. ONCOLOGIST
- Loss of ARID1A in tumor cells renders selective vulnerability to combined ionizing radiation and PARP inhibitor therapy
- (2019) Youngran Park et al. CLINICAL CANCER RESEARCH
- CAR T‐cell therapy: Full speed ahead
- (2019) David Sermer et al. HEMATOLOGICAL ONCOLOGY
- Final analysis of a phase I/IIa trial of the folate‐binding protein‐derived E39 peptide vaccine to prevent recurrence in ovarian and endometrial cancer patients
- (2019) Tommy A. Brown et al. Cancer Medicine
- ARID1A Mutations Are Associated with Increased Immune Activity in Gastrointestinal Cancer
- (2019) Lin Li et al. Cells
- TCGA molecular groups of endometrial cancer: Pooled data about prognosis
- (2019) Antonio Raffone et al. GYNECOLOGIC ONCOLOGY
- Phase II Study of Avelumab in Patients With Mismatch Repair Deficient and Mismatch Repair Proficient Recurrent/Persistent Endometrial Cancer
- (2019) Panagiotis A. Konstantinopoulos et al. JOURNAL OF CLINICAL ONCOLOGY
- Microsatellite-Stable Tumors with High Mutational Burden Benefit from Immunotherapy
- (2019) Aaron M. Goodman et al. Cancer Immunology Research
- The Role of Metabolic Syndrome in Endometrial Cancer: A Review
- (2019) Xiao Yang et al. Frontiers in Oncology
- LBA12Updated results of activity of durvalumab in advanced endometrial cancer (AEC) according to mismatch repair (MMR) status: The phase II PHAEDRA trial (ANZGOG1601)
- (2019) Y Antill et al. ANNALS OF ONCOLOGY
- B7-H4, a promising target for immunotherapy
- (2019) Jia-Yu Wang et al. CELLULAR IMMUNOLOGY
- Correlations between microsatellite instability and the biological behaviour of tumours
- (2019) Guang Yang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Nivolumab Is Effective in Mismatch Repair–Deficient Noncolorectal Cancers: Results From Arm Z1D—A Subprotocol of the NCI-MATCH (EAY131) Study
- (2019) Nilofer S. Azad et al. JOURNAL OF CLINICAL ONCOLOGY
- Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair–Deficient Cancer: Results From the Phase II KEYNOTE-158 Study
- (2019) Aurelien Marabelle et al. JOURNAL OF CLINICAL ONCOLOGY
- Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4
- (2019) Shuang Qin et al. Molecular Cancer
- Mutation-derived Neoantigen-specific T-cell Responses in Multiple Myeloma
- (2019) Deepak Perumal et al. CLINICAL CANCER RESEARCH
- CAR T Cells Targeting MISIIR for the Treatment of Ovarian Cancer and Other Gynecologic Malignancies
- (2019) Alba Rodriguez-Garcia et al. MOLECULAR THERAPY
- Translating anti-CD19 CAR T-Cell therapy into clinical practice for relapsed/refractory diffuse large B-Cell lymphoma
- (2018) Victor A. Chow et al. BLOOD
- Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer
- (2018) Matthew D. Hellmann et al. CANCER CELL
- Therapeutic vaccines and immune checkpoints inhibition options for gynecological cancers
- (2018) Chiara Di Tucci et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Anti-cancer effects of metformin: recent evidences for its role in prevention and treatment of cancer
- (2018) Masoumeh Kheirandish et al. CURRENT DRUG METABOLISM
- A patent review of IDO1 inhibitors for cancer
- (2018) Jae Eun Cheong et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Management Strategies for Recurrent Endometrial Cancer
- (2018) Elizabeth V. Connor et al. Expert Review of Anticancer Therapy
- An NRG Oncology/GOG study of molecular classification for risk prediction in endometrioid endometrial cancer
- (2018) Casey M. Cosgrove et al. GYNECOLOGIC ONCOLOGY
- Targetable Immune Regulatory Molecule Expression in High-Grade Serous Ovarian Carcinomas in African American Women
- (2018) Anne M. Mills et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
- Randomized Phase II Trial of Carboplatin-Paclitaxel Versus Carboplatin-Paclitaxel-Trastuzumab in Uterine Serous Carcinomas That Overexpress Human Epidermal Growth Factor Receptor 2/neu
- (2018) Amanda N. Fader et al. JOURNAL OF CLINICAL ONCOLOGY
- Molecular Determinants of Response to Anti–Programmed Cell Death (PD)-1 and Anti–Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non–Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing
- (2018) Hira Rizvi et al. JOURNAL OF CLINICAL ONCOLOGY
- Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial
- (2018) Thomas Powles et al. LANCET
- Indoleamine 2,3-dioxygenase in endometrial cancer: a targetable mechanism of immune resistance in mismatch repair-deficient and intact endometrial carcinomas
- (2018) Anne Mills et al. MODERN PATHOLOGY
- Refinement of high-risk endometrial cancer classification using DNA damage response biomarkers: a TransPORTEC initiative
- (2018) Aurélie Auguste et al. MODERN PATHOLOGY
- ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade
- (2018) Jianfeng Shen et al. NATURE MEDICINE
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- (2018) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2018) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden
- (2018) Matthew D. Hellmann et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2018) Ferdinandos Skoulidis et al. Cancer Discovery
- Microsatellite instability status determined by next-generation sequencing and compared with PD-L1 and tumor mutational burden in 11,348 patients
- (2018) Ari Vanderwalde et al. Cancer Medicine
- Tremelimumab combined with durvalumab in patients with mesothelioma (NIBIT-MESO-1): an open-label, non-randomised, phase 2 study
- (2018) Luana Calabrò et al. Lancet Respiratory Medicine
- Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer
- (2018) Charles S. Fuchs et al. JAMA Oncology
- Targeting the IDO1 pathway in cancer: from bench to bedside
- (2018) Ming Liu et al. Journal of Hematology & Oncology
- Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
- (2018) Jong-Ho Cha et al. MOLECULAR CELL
- Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
- (2018) Spencer C. Wei et al. Cancer Discovery
- Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3
- (2018) Jun Wang et al. CELL
- Identification of a subset of microsatellite-stable endometrial carcinoma with high PD-L1 and CD8+ lymphocytes
- (2018) Suzanne Crumley et al. MODERN PATHOLOGY
- Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
- (2018) Toszka Bohn et al. NATURE IMMUNOLOGY
- Cancer immunoediting and resistance to T cell-based immunotherapy
- (2018) Jake S. O’Donnell et al. Nature Reviews Clinical Oncology
- Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4
- (2018) Ryan Kolb et al. ONCOGENE
- Chimeric antigen receptor (CAR) T therapies for the treatment of hematologic malignancies: clinical perspective and significance
- (2018) Michael M. Boyiadzis et al. Journal for ImmunoTherapy of Cancer
- The Emerging Role of the Microenvironment in Endometrial Cancer
- (2018) Subhransu Sahoo et al. Cancers
- Molecular Genetics of Endometrial Carcinoma
- (2018) Daphne W. Bell et al. Annual Review of Pathology-Mechanisms of Disease
- Polymerase ε (POLE) ultra-mutation in uterine tumors correlates with T lymphocyte infiltration and increased resistance to platinum-based chemotherapy in vitro
- (2017) Stefania Bellone et al. GYNECOLOGIC ONCOLOGY
- Characterization of immune regulatory molecules B7-H4 and PD-L1 in low and high grade endometrial tumors
- (2017) Amy Bregar et al. GYNECOLOGIC ONCOLOGY
- Effects of metformin on endometrial cancer: Systematic review and meta-analysis
- (2017) Cinthia G. Meireles et al. GYNECOLOGIC ONCOLOGY
- Metformin is associated with reduced cell proliferation in human endometrial cancer by inbibiting PI3K/AKT/mTOR signaling
- (2017) Yan Zhao et al. GYNECOLOGICAL ENDOCRINOLOGY
- Tim-3 and its role in regulating anti-tumor immunity
- (2017) Madhumita Das et al. IMMUNOLOGICAL REVIEWS
- TIM-3 as a Target for Cancer Immunotherapy and Mechanisms of Action
- (2017) Wenwen Du et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Safety and Activity of Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha–Targeting Antibody–Drug Conjugate, in Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer: A Phase I Expansion Study
- (2017) Kathleen N. Moore et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Trial of Atezolizumab As First-Line or Subsequent Therapy for Patients With Programmed Death-Ligand 1–Selected Advanced Non–Small-Cell Lung Cancer (BIRCH)
- (2017) Solange Peters et al. JOURNAL OF CLINICAL ONCOLOGY
- Safety and Antitumor Activity of Pembrolizumab in Advanced Programmed Death Ligand 1–Positive Endometrial Cancer: Results From the KEYNOTE-028 Study
- (2017) Patrick A. Ott et al. JOURNAL OF CLINICAL ONCOLOGY
- Pembrolizumab in Patients With Extensive-Stage Small-Cell Lung Cancer: Results From the Phase Ib KEYNOTE-028 Study
- (2017) Patrick A. Ott et al. JOURNAL OF CLINICAL ONCOLOGY
- International Patterns and Trends in Endometrial Cancer Incidence, 1978–2013
- (2017) Joannie Lortet-Tieulent et al. JNCI-Journal of the National Cancer Institute
- Tremelimumab as second-line or third-line treatment in relapsed malignant mesothelioma (DETERMINE): a multicentre, international, randomised, double-blind, placebo-controlled phase 2b trial
- (2017) Michele Maio et al. LANCET ONCOLOGY
- High efficacy and safety of low-dose CD19-directed CAR-T cell therapy in 51 refractory or relapsed B acute lymphoblastic leukemia patients
- (2017) J Pan et al. LEUKEMIA
- Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers
- (2017) Aaron M. Goodman et al. MOLECULAR CANCER THERAPEUTICS
- An immunogenic personal neoantigen vaccine for patients with melanoma
- (2017) Patrick A. Ott et al. NATURE
- Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma
- (2017) Jedd D. Wolchok et al. NEW ENGLAND JOURNAL OF MEDICINE
- First-Line Nivolumab in Stage IV or Recurrent Non–Small-Cell Lung Cancer
- (2017) David P. Carbone et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma
- (2017) Joaquim Bellmunt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
- (2017) Martin Lauss et al. Nature Communications
- Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
- (2017) Zachary R. Chalmers et al. Genome Medicine
- Strong Correlation of Indoleamine 2,3-Dioxygenase 1 Expression with Basal-Like Phenotype and Increased Lymphocytic Infiltration in Triple-Negative Breast Cancer
- (2017) Sewha Kim et al. Journal of Cancer
- International Patterns and Trends in Endometrial Cancer Incidence, 1978–2013
- (2017) Joannie Lortet-Tieulent et al. JNCI-Journal of the National Cancer Institute
- The Roles of Glycodelin in Cancer Development and Progression
- (2017) Juan Cui et al. Frontiers in Immunology
- Immunological profiling of molecularly classified high-risk endometrial cancers identifies POLE-mutant and microsatellite unstable carcinomas as candidates for checkpoint inhibition
- (2017) Florine A. Eggink et al. OncoImmunology
- Solitomab, an EpCAM/CD3 bispecific antibody construct (BiTE), is highly active against primary uterine serous papillary carcinoma cell lines in vitro
- (2016) Stefania Bellone et al. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Measuring the biological effect of presurgical metformin treatment in endometrial cancer
- (2016) V N Sivalingam et al. BRITISH JOURNAL OF CANCER
- Tumor genotype and immune microenvironment in POLE-ultramutated and MSI-hypermutated Endometrial Cancers: New candidates for checkpoint blockade immunotherapy?
- (2016) Piera Gargiulo et al. CANCER TREATMENT REVIEWS
- Endometrial Carcinomas with POLE Exonuclease Domain Mutations Have a Favorable Prognosis
- (2016) M. K. McConechy et al. CLINICAL CANCER RESEARCH
- Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer—Combined Analysis of the PORTEC Cohorts
- (2016) Ellen Stelloo et al. CLINICAL CANCER RESEARCH
- Differential Expression and Significance of PD-L1, IDO-1, and B7-H4 in Human Lung Cancer
- (2016) Kurt A. Schalper et al. CLINICAL CANCER RESEARCH
- Progesterone receptor expression is associated with longer overall survival within high-grade histotypes of endometrial carcinoma: A Canadian high risk endometrial cancer consortium (CHREC) study
- (2016) Martin Köbel et al. GYNECOLOGIC ONCOLOGY
- B7-H4 expression in ovarian serous carcinoma: a study of 306 cases
- (2016) Li Liang et al. HUMAN PATHOLOGY
- Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
- (2016) Ana C. Anderson et al. IMMUNITY
- The role of neoantigens in response to immune checkpoint blockade
- (2016) Nadeem Riaz et al. INTERNATIONAL IMMUNOLOGY
- Obesity and Cancer Mechanisms: Tumor Microenvironment and Inflammation
- (2016) Neil M. Iyengar et al. JOURNAL OF CLINICAL ONCOLOGY
- Protection of mitochondria prevents high-fat diet–induced glomerulopathy and proximal tubular injury
- (2016) Hazel H. Szeto et al. KIDNEY INTERNATIONAL
- Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
- (2016) Roy S Herbst et al. LANCET
- Endometrial cancer
- (2016) Philippe Morice et al. LANCET
- Safety and antitumour activity of durvalumab plus tremelimumab in non-small cell lung cancer: a multicentre, phase 1b study
- (2016) Scott Antonia et al. LANCET ONCOLOGY
- Pembrolizumab for patients with PD-L1-positive advanced gastric cancer (KEYNOTE-012): a multicentre, open-label, phase 1b trial
- (2016) Kei Muro et al. LANCET ONCOLOGY
- B7-H4 expression in human infiltrating ductal carcinoma-associated macrophages
- (2016) Lei Liu et al. Molecular Medicine Reports
- Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
- (2016) Giampaolo Bianchini et al. Nature Reviews Clinical Oncology
- The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
- (2016) Danny N. Khalil et al. Nature Reviews Clinical Oncology
- Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway
- (2016) Vassiliki A. Boussiotis NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
- (2016) Robert L. Ferris et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
- (2016) Martin Reck et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tumour-infiltrating lymphocytes in melanoma prognosis and cancer immunotherapy
- (2016) Nayoung Lee et al. PATHOLOGY
- Correction: Tim-3 Expression in Cervical Cancer Promotes Tumor Metastasis
- (2016) Yang Cao et al. PLoS One
- B7-H3 and B7-H4 are independent predictors of a poor prognosis in patients with pancreatic cancer
- (2016) HONG XU et al. Oncology Letters
- Toward Repurposing Metformin as a Precision Anti-Cancer Therapy Using Structural Systems Pharmacology
- (2016) Thomas Hart et al. Scientific Reports
- Quantitative Assessment of the Heterogeneity of PD-L1 Expression in Non–Small-Cell Lung Cancer
- (2016) Joseph McLaughlin et al. JAMA Oncology
- Clinical significance of tumor-infiltrating lymphocytes in breast cancer
- (2016) Sasha E. Stanton et al. Journal for ImmunoTherapy of Cancer
- Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
- (2015) Suzanne L. Topalian et al. CANCER CELL
- Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy
- (2015) P. Maby et al. CANCER RESEARCH
- Estrogen receptors regulate innate immune cells and signaling pathways
- (2015) Susan Kovats CELLULAR IMMUNOLOGY
- Glycodelin: A New Biomarker with Immunomodulatory Functions in Non-Small Cell Lung Cancer
- (2015) M. A. Schneider et al. CLINICAL CANCER RESEARCH
- Dual blockade of PI3K/AKT/mTOR (NVP-BEZ235) and Ras/Raf/MEK (AZD6244) pathways synergistically inhibit growth of primary endometrioid endometrial carcinoma cultures, whereas NVP-BEZ235 reduces tumor growth in the corresponding xenograft models
- (2015) Stefanie Schrauwen et al. GYNECOLOGIC ONCOLOGY
- Phase III randomized trial of second-line ixabepilone versus paclitaxel or doxorubicin in women with advanced endometrial cancer
- (2015) Scott McMeekin et al. GYNECOLOGIC ONCOLOGY
- Intratumoral CD8+ Lymphocyte Infiltration as a Prognostic Factor and Its Relationship With Cyclooxygenase 2 Expression and Microsatellite Instability in Endometrial Cancer
- (2015) Tomohiro Suemori et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Deficient mismatch repair: Read all about it (Review)
- (2015) SUSAN RICHMAN INTERNATIONAL JOURNAL OF ONCOLOGY
- Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes
- (2015) Cyrille J. Cohen et al. JOURNAL OF CLINICAL INVESTIGATION
- Cancer immunotherapy: harnessing the immune system to battle cancer
- (2015) Yiping Yang JOURNAL OF CLINICAL INVESTIGATION
- The immune system in the normal endometrium and implications for endometrial cancer development
- (2015) A. Vanderstraeten et al. JOURNAL OF REPRODUCTIVE IMMUNOLOGY
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- (2015) Ellen Stelloo et al. MODERN PATHOLOGY
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- (2015) S. P. Patel et al. MOLECULAR CANCER THERAPEUTICS
- Cancer immunotherapy utilizing gene-modified T cells: From the bench to the clinic
- (2015) Connie P.M. Duong et al. MOLECULAR IMMUNOLOGY
- Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
- (2015) Timothy A. Chan et al. NEW ENGLAND JOURNAL OF MEDICINE
- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
- (2015) Dung T. Le et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immune-mediated antitumor effect by type 2 diabetes drug, metformin
- (2015) Shingo Eikawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer
- (2015) David Pépin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Anti-cancer effect of metformin by suppressing signaling pathway of HER2 and HER3 in tamoxifen-resistant breast cancer cells
- (2015) Jinkyoung Kim et al. TUMOR BIOLOGY
- Expression of immune checkpoint molecules in endometrial carcinoma
- (2015) JIA LIU et al. Experimental and Therapeutic Medicine
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- (2015) J. Shen et al. Cancer Discovery
- Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1
- (2015) Brooke E. Howitt et al. JAMA Oncology
- Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy
- (2014) Ravi V. J. Chari et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells
- (2014) Aki Miyasaka et al. BMC CANCER
- Predicting response and survival in chemotherapy-treated triple-negative breast cancer
- (2014) A Prat et al. BRITISH JOURNAL OF CANCER
- Solitomab, an epithelial cell adhesion molecule/CD3 bispecific antibody (BiTE), is highly active against primary chemotherapy-resistant ovarian cancer cell lines in vitro and fresh tumor cells ex vivo
- (2014) Diana P. English et al. CANCER
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- (2014) Anke Vanderstraeten et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
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- (2014) Sandra Van Lint et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells
- (2014) J. Zhang et al. EUROPEAN JOURNAL OF HISTOCHEMISTRY
- B7-H4 as a potential target for immunotherapy for gynecologic cancers: A closer look
- (2014) Jenessa B. Smith et al. GYNECOLOGIC ONCOLOGY
- POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium
- (2014) Bo Meng et al. GYNECOLOGIC ONCOLOGY
- Estrogen receptor β: the guardian of the endometrium
- (2014) D.K. Hapangama et al. HUMAN REPRODUCTION UPDATE
- Cox-2, EGFR, and ERBB-2 Expression in Cervical Intraepithelial Neoplasia and Cervical Cancer Using an Automated Imaging System
- (2014) Elza M. Fukazawa et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
- Endometrial NK Cells Are Special Immature Cells That Await Pregnancy
- (2014) I. Manaster et al. JOURNAL OF IMMUNOLOGY
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- (2014) L. Arruvito et al. JOURNAL OF IMMUNOLOGY
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- (2014) David N. Church et al. JNCI-Journal of the National Cancer Institute
- Classification of endometrial carcinoma: more than two types
- (2014) Rajmohan Murali et al. LANCET ONCOLOGY
- Impact of microsatellite instability on survival of endometrial cancer patients
- (2014) Daiva Kanopienė et al. Medicina-Lithuania
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
- (2014) Alexandra Snyder et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
- (2014) Nicolas J. Llosa et al. Cancer Discovery
- Adipose tissue and adipocytes support tumorigenesis and metastasis
- (2013) Kristin M. Nieman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Immunosuppressive Glycodelin A is an independent marker for poor prognosis in endometrial cancer
- (2013) Miriam Lenhard et al. BMC CANCER
- The Emerging Genomic Landscape of Endometrial Cancer
- (2013) M. Le Gallo et al. CLINICAL CHEMISTRY
- Mismatch repair status and clinical outcome in endometrial cancer: A systematic review and meta-analysis
- (2013) Ivan Diaz-Padilla et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- From the immune contexture to the Immunoscore: the role of prognostic and predictive immune markers in cancer
- (2013) Helen Angell et al. CURRENT OPINION IN IMMUNOLOGY
- Progesterone Action in Endometrial Cancer, Endometriosis, Uterine Fibroids, and Breast Cancer
- (2013) J. Julie Kim et al. ENDOCRINE REVIEWS
- Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial
- (2013) Jone Trovik et al. EUROPEAN JOURNAL OF CANCER
- Progesterone receptor negativity is an independent risk factor for relapse in patients with early stage endometrioid endometrial adenocarcinoma
- (2013) Jutta Huvila et al. GYNECOLOGIC ONCOLOGY
- Histological and immunohistochemical profiles predict lymph node status in women with low-intermediate risk endometrial cancer
- (2013) Marcos Ballester et al. GYNECOLOGIC ONCOLOGY
- Adoptive T Cell Transfer for Cancer Immunotherapy in the Era of Synthetic Biology
- (2013) Michael Kalos et al. IMMUNITY
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- (2013) Marco Ruella et al. IMMUNOLOGICAL REVIEWS
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- (2013) G. K. Chimal-Ramírez et al. Journal of Oncology
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- (2011) A. M. Paterson et al. JOURNAL OF IMMUNOLOGY
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- (2011) D.K. Hickey et al. JOURNAL OF REPRODUCTIVE IMMUNOLOGY
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- (2011) D. Bell et al. NATURE
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- (2011) R. D. Schreiber et al. SCIENCE
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- (2010) Charles R. Wira et al. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
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- (2010) Marina Pierdominici et al. IMMUNOLOGY LETTERS
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- (2010) Daniel O. Ochiel et al. JOURNAL OF LEUKOCYTE BIOLOGY
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- (2010) M. Lopus et al. MOLECULAR CANCER THERAPEUTICS
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- (2010) E. Oroudjev et al. MOLECULAR CANCER THERAPEUTICS
- Tumor Delivery and In Vivo Processing of Disulfide-Linked and Thioether-Linked Antibody−Maytansinoid Conjugates
- (2009) Hans K. Erickson et al. BIOCONJUGATE CHEMISTRY
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- (2009) R.A. de Jong et al. GYNECOLOGIC ONCOLOGY
- Phase II trial of trastuzumab in women with advanced or recurrent, HER2-positive endometrial carcinoma: A Gynecologic Oncology Group study
- (2009) Gini F. Fleming et al. GYNECOLOGIC ONCOLOGY
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- (2009) Agnieszka K. Witkiewicz et al. HUMAN PATHOLOGY
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- (2009) Pravin T.P. Kaumaya et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2008) N. H. Segal et al. CANCER RESEARCH
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- (2008) S. Ogino et al. CLINICAL CANCER RESEARCH
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- (2008) M Seppälä et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
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- (2008) Alexandra Giatromanolaki et al. GYNECOLOGIC ONCOLOGY
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- (2008) Marco A. De León-Nava et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
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- (2008) Alberto Mantovani et al. NATURE
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- (2007) T.A. Grushko et al. GYNECOLOGIC ONCOLOGY
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