ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade
Authors
Keywords
-
Journal
NATURE MEDICINE
Volume 24, Issue 5, Pages 556-562
Publisher
Springer Nature
Online
2018-05-04
DOI
10.1038/s41591-018-0012-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing
- (2018) Deng Pan et al. SCIENCE
- Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma
- (2018) Diana Miao et al. SCIENCE
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice
- (2016) Radhika Mathur et al. NATURE GENETICS
- Classification and characterization of microsatellite instability across 18 cancer types
- (2016) Ronald J Hause et al. NATURE MEDICINE
- The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
- (2016) Danny N. Khalil et al. Nature Reviews Clinical Oncology
- Recent developments and future challenges in immune checkpoint inhibitory cancer treatment
- (2015) Bas D. Koster et al. CURRENT OPINION IN ONCOLOGY
- Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
- (2015) Dongjun Peng et al. NATURE
- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
- (2015) Dung T. Le et al. NEW ENGLAND JOURNAL OF MEDICINE
- Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy
- (2015) Mihaela Angelova et al. GENOME BIOLOGY
- The emerging roles of ARID1A in tumor suppression
- (2014) Ren-Chin Wu et al. CANCER BIOLOGY & THERAPY
- Loss of ARID1A expression in colorectal carcinoma is strongly associated with mismatch repair deficiency
- (2014) Angela Chou et al. HUMAN PATHOLOGY
- Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
- (2014) Roy S. Herbst et al. NATURE
- Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis
- (2014) Z. D. Nagel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
- (2014) Nicolas J. Llosa et al. Cancer Discovery
- The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα
- (2013) Feng Li et al. CELL
- Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
- (2013) Gabriela Bindea et al. IMMUNITY
- ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas
- (2013) Ghassan Allo et al. MODERN PATHOLOGY
- Mutational landscape and significance across 12 major cancer types
- (2013) Cyriac Kandoth et al. NATURE
- Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
- (2013) Kristian Cibulskis et al. NATURE BIOTECHNOLOGY
- Loss of ARID1A expression is uncommon in gastric, colorectal, and prostate cancers
- (2012) Min Sung Kim et al. APMIS
- A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff
- (2012) Pablo Cingolani et al. FLY
- ARID1A Mutations in Cancer: Another Epigenetic Tumor Suppressor?
- (2012) Jennifer N. Wu et al. Cancer Discovery
- Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
- (2011) Kai Wang et al. NATURE GENETICS
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines
- (2008) P. Romano et al. NUCLEIC ACIDS RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More