Curcumin Reverses NNMT-Induced 5-Fluorouracil Resistance via Increasing ROS and Cell Cycle Arrest in Colorectal Cancer Cells

Curcumin Nanoparticle Enhances the Anticancer Effect of Cisplatin by Inhibiting PI3K/AKT and JAK/STAT3 Pathway in Rat Ovarian Carcinoma Induced by DMBA

(2021) Ni Made Dwi Sandhiutami et al.   Frontiers in Pharmacology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Plant-Derived Anticancer Compounds as New Perspectives in Drug Discovery and Alternative Therapy

(2021) Cristina Adriana Dehelean et al.   MOLECULES

Curcumin inhibits the growth of liver cancer by impairing myeloid‑derived suppressor cells in murine tumor tissues

(2021) Sha Tian et al.   Oncology Letters

Vanillin downregulates NNMT and attenuates NNMT‑related resistance to 5‑fluorouracil via ROS‑induced cell apoptosis in colorectal cancer cells

(2021) Guoli Li et al.   ONCOLOGY REPORTS

Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells

(2020) Haitao Yu et al.   Cancer Cell International

Curcumin and Colorectal Cancer: From Basic to Clinical Evidences

(2020) Maria Pricci et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ginsenoside panaxatriol reverses TNBC paclitaxel resistance by inhibiting the IRAK1/NF-κB and ERK pathways

(2020) Panpan Wang et al.   PeerJ

Enhanced anti‐tumor effects of the PD‐1 blockade combined with a highly absorptive form of curcumin targeting STAT3

(2020) Taeko Hayakawa et al.   CANCER SCIENCE

Curcumin induced apoptosis is mediated through oxidative stress in mutated p53 and wild type p53 colon adenocarcinoma cell lines

(2020) Sruthi Sritharan et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Curcumin: A therapeutic strategy for colorectal cancer?

(2020) Vicenç Ruiz de Porras et al.   SEMINARS IN CANCER BIOLOGY

Synergistic effects of curcumin and its analogs with other bioactive compounds: A comprehensive review

(2020) Maryam Sadat Hosseini-Zare et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The inhibitory effect of curcumin via fascin suppression through JAK/STAT3 pathway on metastasis and recurrence of ovary cancer cells

(2020) Mi Ju Kim et al.   BMC Womens Health

Mechanism of Apoptosis Induced by Curcumin in Colorectal Cancer

(2019) Nor Isnida Ismail et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Colorectal cancer

(2019) Evelien Dekker et al.   LANCET

Molecular mechanisms of curcumin and its analogs in colon cancer prevention and treatment

(2019) Chelliah Selvam et al.   LIFE SCIENCES

Biochemical and Biophysical characterization of curcumin binding to human mitotic kinesin Eg5: Insights into the inhibitory mechanism of curcumin on Eg5

(2018) Darpan Raghav et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Curcumin induces apoptosis and cell cycle arrest via the activation of reactive oxygen species–independent mitochondrial apoptotic pathway in Smad4 and p53 mutated colon adenocarcinoma HT29 cells

(2018) Ayushi Agarwal et al.   NUTRITION RESEARCH

Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation

(2018) Hung-Hua Liang et al.   LIFE SCIENCES

Nicotinamide N -Methyltransferase: More Than a Vitamin B3 Clearance Enzyme

(2017) Pavlos Pissios   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Curcumin induces G2/M arrest and triggers apoptosis via FoxO1 signaling in U87 human glioma cells

(2016) CHAO CHENG et al.   Molecular Medicine Reports

Cytotoxicity of withasteroids: withametelin induces cell cycle arrest at G2/M phase and mitochondria-mediated apoptosis in non-small cell lung cancer A549 cells

(2016) Poorna Chandra Rao et al.   TUMOR BIOLOGY

Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway

(2016) Xinyou Xie et al.   Oncotarget

Nicotinamide N-methyltransferase enhances the capacity of tumorigenesis associated with the promotion of cell cycle progression in human colorectal cancer cells

(2014) Xinyou Xie et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The IL-6/JAK/STAT3 pathway: Potential therapeutic strategies in treating colorectal cancer

(2014) SHU-WEI WANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Down-Regulation of Nicotinamide N-methyltransferase Induces Apoptosis in Human Breast Cancer Cells via the Mitochondria-Mediated Pathway

(2014) Jun Zhang et al.   PLoS One

Evodiamine Induces G2/M Arrest and Apoptosis via Mitochondrial and Endoplasmic Reticulum Pathways in H446 and H1688 Human Small-Cell Lung Cancer Cells

(2014) Chunshu Fang et al.   PLoS One

Cyclin-dependent kinases

(2014) Marcos Malumbres   GENOME BIOLOGY

Molecular mechanisms underlying RB protein function

(2013) Frederick A. Dick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

(−)-Anonaine Induces DNA Damage and Inhibits Growth and Migration of Human Lung Carcinoma H1299 Cells

(2011) Bing-Hung Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Curcumin-Induced Mitotic Spindle Defect and Cell Cycle Arrest in Human Bladder Cancer Cells Occurs Partly through Inhibition of Aurora A

(2011) H.-S. Liu et al.   MOLECULAR PHARMACOLOGY

A novel polysaccharide from Se-enriched Ganoderma lucidum induces apoptosis of human breast cancer cells

(2010) Shang   ONCOLOGY REPORTS